Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   D4H43_RS04795 Genome accession   NZ_CP032911
Coordinates   988241..990025 (+) Length   594 a.a.
NCBI ID   WP_139544183.1    Uniprot ID   -
Organism   Helicobacter pylori strain 19-A-EK3     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 983241..995025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4H43_RS04765 motB 984005..984778 (+) 774 WP_128065536.1 flagellar motor protein MotB -
  D4H43_RS04770 - 984784..985221 (+) 438 WP_001875392.1 hypothetical protein -
  D4H43_RS04775 - 985290..986951 (+) 1662 WP_139544649.1 ABC transporter permease/substrate-binding protein -
  D4H43_RS04780 - 986955..987605 (+) 651 WP_139544181.1 ATP-binding cassette domain-containing protein -
  D4H43_RS04785 - 987608..987787 (-) 180 WP_000468793.1 hypothetical protein -
  D4H43_RS04790 - 987779..988240 (+) 462 WP_139544182.1 hypothetical protein -
  D4H43_RS04795 uvrC 988241..990025 (+) 1785 WP_139544183.1 excinuclease ABC subunit UvrC Machinery gene
  D4H43_RS04800 - 990036..991301 (+) 1266 WP_139544184.1 homoserine dehydrogenase -
  D4H43_RS04805 - 991302..991646 (+) 345 WP_001211686.1 YraN family protein -
  D4H43_RS04810 trxA 991735..992055 (+) 321 WP_000020199.1 thioredoxin -
  D4H43_RS04815 trxB 992060..992995 (+) 936 WP_139544185.1 thioredoxin-disulfide reductase -
  D4H43_RS04820 - 993352..994173 (+) 822 WP_139544186.1 glycosyltransferase family 25 protein -
  D4H43_RS04825 - 994379..994627 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68647.94 Da        Isoelectric Point: 9.6979

>NTDB_id=320308 D4H43_RS04795 WP_139544183.1 988241..990025(+) (uvrC) [Helicobacter pylori strain 19-A-EK3]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNYRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLN
ACSNEALKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEETRSLFKLECMPYRVEIFDT
SHHSSSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=320308 D4H43_RS04795 WP_139544183.1 988241..990025(+) (uvrC) [Helicobacter pylori strain 19-A-EK3]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAACGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATTATCGCGCTAGCTTACGCATTCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACGATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACAAGCGGGGCTAAAGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGCTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCTCTCATTTACAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCTGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTAATACCAGAACAGATTTTATTGAAC
GCTTGCTCTAACGAAGCGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAACGCGATCGCTCTTTAAATTAGAGTGCATGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCTAGCAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCCTTCCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

98.485

100

0.985

Multiple sequence alignment