Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   D4I31_RS05035 Genome accession   NZ_CP032908
Coordinates   1046602..1048386 (+) Length   594 a.a.
NCBI ID   WP_139534905.1    Uniprot ID   -
Organism   Helicobacter pylori strain 23-A-EK1     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1041602..1053386
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4I31_RS05000 - 1041751..1042002 (+) 252 Protein_967 osmoprotection protein -
  D4I31_RS05005 - 1042016..1042588 (-) 573 WP_139534895.1 Hpy99I family type II restriction endonuclease -
  D4I31_RS05010 - 1042582..1043400 (-) 819 WP_139534897.1 site-specific DNA-methyltransferase -
  D4I31_RS05015 - 1043651..1045312 (+) 1662 WP_139534899.1 ABC transporter permease/substrate-binding protein -
  D4I31_RS05020 - 1045316..1045957 (+) 642 WP_139534901.1 ATP-binding cassette domain-containing protein -
  D4I31_RS05025 - 1045969..1046148 (-) 180 WP_000468794.1 hypothetical protein -
  D4I31_RS05030 - 1046140..1046601 (+) 462 WP_139534903.1 hypothetical protein -
  D4I31_RS05035 uvrC 1046602..1048386 (+) 1785 WP_139534905.1 excinuclease ABC subunit UvrC Machinery gene
  D4I31_RS05040 - 1048397..1049662 (+) 1266 WP_139534906.1 homoserine dehydrogenase -
  D4I31_RS05045 - 1049663..1050007 (+) 345 WP_001211720.1 YraN family protein -
  D4I31_RS05050 trxA 1050096..1050416 (+) 321 WP_000020199.1 thioredoxin -
  D4I31_RS05055 trxB 1050422..1051357 (+) 936 WP_000564419.1 thioredoxin-disulfide reductase -
  D4I31_RS05060 - 1051567..1052388 (+) 822 WP_139534907.1 glycosyltransferase family 25 protein -
  D4I31_RS05065 - 1052609..1052857 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68574.81 Da        Isoelectric Point: 9.6260

>NTDB_id=320258 D4I31_RS05035 WP_139534905.1 1046602..1048386(+) (uvrC) [Helicobacter pylori strain 23-A-EK1]
MADLLSSLKNLPNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIHNNEITPNPRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYSKIAKKCLEMIENKDKLIKELELKMECLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLIPEQILLS
TCSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENHAFQKDSYRRYHLKGSDEYTQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPNNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=320258 D4I31_RS05035 WP_139534905.1 1046602..1048386(+) (uvrC) [Helicobacter pylori strain 23-A-EK1]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTCCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCATAACAATGAAATCACGCCCA
ATCCTCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAAAATGTTTAGAAATGATTGAAAATAAAGACAAGCTCATCAAAGAGCTTGAATTAA
AAATGGAGTGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTAATTTATAGGGACAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAAGCGGT
CTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATACCAGAACAGATTTTATTGAGC
ACTTGTTCTAATGAAACGCTTAAGGAATTGCAAGAGTTTATCTCCCATCAATATTCTAAAAAAATCGCTCTTAGTATTCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAGGTGCGATCGCTCTTTAATTTAGAGTGCGTGCCGTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTTCAAAAAGACTCTTATCGGCG
CTACCATCTAAAAGGCTCTGATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTAATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGTGCTAAAGACATTAT
CCATACGCCTAACAATACTTTTAAATTGCTCCCTAGCGACAAGCGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.97

100

0.97

Multiple sequence alignment