Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   D4K04_RS04925 Genome accession   NZ_CP032904
Coordinates   1009360..1011144 (+) Length   594 a.a.
NCBI ID   WP_139521980.1    Uniprot ID   -
Organism   Helicobacter pylori strain 169-A-EK5     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1004360..1016144
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4K04_RS04895 motB 1005124..1005897 (+) 774 WP_139521978.1 flagellar motor protein MotB -
  D4K04_RS04900 - 1005903..1006340 (+) 438 WP_000802458.1 hypothetical protein -
  D4K04_RS04905 - 1006409..1008070 (+) 1662 WP_139522336.1 ABC transporter permease/substrate-binding protein -
  D4K04_RS04910 - 1008074..1008715 (+) 642 WP_000659431.1 ATP-binding cassette domain-containing protein -
  D4K04_RS04915 - 1008727..1008906 (-) 180 WP_000468794.1 hypothetical protein -
  D4K04_RS04920 - 1008898..1009359 (+) 462 WP_139521979.1 hypothetical protein -
  D4K04_RS04925 uvrC 1009360..1011144 (+) 1785 WP_139521980.1 excinuclease ABC subunit UvrC Machinery gene
  D4K04_RS04930 - 1011155..1012420 (+) 1266 WP_139521981.1 homoserine dehydrogenase -
  D4K04_RS04935 - 1012421..1012765 (+) 345 WP_139521982.1 YraN family protein -
  D4K04_RS04940 trxA 1012854..1013174 (+) 321 WP_000020199.1 thioredoxin -
  D4K04_RS04945 trxB 1013180..1014115 (+) 936 WP_000564420.1 thioredoxin-disulfide reductase -
  D4K04_RS04950 - 1014486..1015307 (+) 822 WP_139521983.1 glycosyltransferase family 25 protein -
  D4K04_RS04955 - 1015520..1015768 (-) 249 WP_000790557.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68693.90 Da        Isoelectric Point: 9.7127

>NTDB_id=320176 D4K04_RS04925 WP_139521980.1 1009360..1011144(+) (uvrC) [Helicobacter pylori strain 169-A-EK5]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYSKIAKECLEMIENKDRLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNEVLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFKLECVPYRVEIFDT
SHHSNSQCVGGMVVYENHAFQKDSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=320176 D4K04_RS04925 WP_139521980.1 1009360..1011144(+) (uvrC) [Helicobacter pylori strain 169-A-EK5]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAACAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ACCATCGTGCTAGCTTACGAATTCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAACTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCTTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTCAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCTCTGATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CTGATGAGGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATTCTATTAAAC
GCTTGCTCTAACGAAGTGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTCAAATTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGCATTTCAAAAAGACTCTTATCGGCG
CTACCATTTGAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACTAGAAGAGCTTTAGATTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTAATAGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.643

100

0.976

Multiple sequence alignment