Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/comE3   Type   Machinery gene
Locus tag   D4K40_RS00875 Genome accession   NZ_CP032902
Coordinates   178483..179796 (+) Length   437 a.a.
NCBI ID   WP_201737304.1    Uniprot ID   -
Organism   Helicobacter pylori strain 280-A-EK1     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 168086..179796 178483..179796 within 0


Gene organization within MGE regions


Location: 168086..179796
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4K40_RS00835 - 168086..170551 (-) 2466 WP_139521218.1 site-specific DNA-methyltransferase -
  D4K40_RS00840 - 170797..171659 (+) 863 Protein_159 site-specific DNA-methyltransferase -
  D4K40_RS00845 - 171646..172426 (+) 781 Protein_160 site-specific DNA-methyltransferase -
  D4K40_RS00850 - 172442..173714 (+) 1273 Protein_161 restriction endonuclease subunit R -
  D4K40_RS00855 crdR 173797..174438 (+) 642 WP_120993530.1 copper response regulator transcription factor CrdR -
  D4K40_RS00860 crdS 174419..175606 (+) 1188 WP_139520341.1 copper-sensing histidine kinase CrdS -
  D4K40_RS00865 - 175609..177009 (+) 1401 WP_139520342.1 NAD(P)H-hydrate dehydratase -
  D4K40_RS00870 - 177020..178486 (+) 1467 WP_139520343.1 replicative DNA helicase -
  D4K40_RS00875 comEC/comE3 178483..179796 (+) 1314 WP_201737304.1 ComEC/Rec2 family competence protein Machinery gene

Sequence

Protein


Download         Length: 437 a.a.        Molecular weight: 50255.23 Da        Isoelectric Point: 9.9086

>NTDB_id=320117 D4K40_RS00875 WP_201737304.1 178483..179796(+) (comEC/comE3) [Helicobacter pylori strain 280-A-EK1]
MKDKTFQGAFELLATPKEYLWCGVFLSLLLAINLYLEYLNYQKLDFSKPTSLSAQILLQYPKTKDQKTYFVLKLQSKNMI
FYTTIKEPLKNLQYRHAQFFGKFKPCSFLESLKSCFFQTYSFSLTRKQDFKSRLRHFIDSAHSSALVSNLYRALFIGDSL
NKDLRDRANALGINHLLAISGFHLGILSVSVYFLFSLFYTPLQKRYFPYRNAFYDIGVLVWVFLLGYLLLLDFLPSFFRA
FLMGLLGFLACFFGVRLLSFKLLILACCIAIALLPKLLFSVGFLLSVCGVWYIFLFLKHTQAFFKTSSFLRRSFQVISLS
VLVFLNMLIIVHAFFPMFSPYQLFSIPLGLIFIVFFPLSLFLHAVGLGSLLDHILSMPLTIPTISIPSPLWLLGAHLCLT
ILSARSFKVYLSMNVLSAGFFLYCCYQYIIMPSLIVG

Nucleotide


Download         Length: 1314 bp        

>NTDB_id=320117 D4K40_RS00875 WP_201737304.1 178483..179796(+) (comEC/comE3) [Helicobacter pylori strain 280-A-EK1]
TTGAAAGACAAAACTTTTCAGGGGGCGTTTGAACTTCTTGCAACCCCCAAAGAATACTTATGGTGTGGGGTGTTTTTAAG
CCTTTTGTTGGCAATCAATCTTTATTTAGAATATTTGAATTACCAAAAGCTTGATTTTTCAAAACCTACAAGCTTGAGCG
CTCAAATCTTGTTGCAATACCCCAAAACTAAAGATCAAAAAACCTATTTTGTTTTAAAGCTCCAATCAAAAAACATGATC
TTTTACACCACCATTAAAGAGCCTTTAAAAAACCTCCAATACCGCCATGCGCAATTTTTTGGTAAGTTCAAACCCTGCTC
GTTCTTAGAGTCTCTAAAATCATGCTTTTTTCAAACTTATTCTTTTTCTTTAACACGAAAACAAGATTTTAAATCGCGTT
TGCGCCATTTCATTGACAGCGCTCATTCAAGCGCTTTAGTGAGCAATTTGTATCGCGCGTTATTTATAGGGGATAGCTTG
AATAAAGATTTAAGAGACAGGGCTAACGCGCTAGGGATCAACCACTTACTAGCCATTAGCGGGTTCCATTTAGGGATTTT
GAGCGTTAGCGTGTATTTTCTTTTTTCGCTTTTTTATACCCCCTTACAAAAACGCTATTTCCCTTACAGGAACGCTTTTT
ATGATATAGGGGTTTTGGTGTGGGTTTTTTTGCTAGGGTATTTATTGCTATTGGATTTTTTACCCTCTTTTTTCAGGGCG
TTTTTAATGGGCTTATTAGGGTTTTTGGCATGCTTTTTTGGGGTAAGGCTTTTGAGTTTTAAACTTTTGATTTTAGCGTG
CTGTATCGCCATAGCGTTACTCCCTAAATTGCTTTTTAGCGTGGGGTTTTTGCTTTCTGTTTGTGGGGTGTGGTATATCT
TTTTATTCTTAAAACACACTCAAGCCTTTTTTAAAACCTCTTCTTTTTTAAGGCGATCTTTTCAAGTCATAAGCTTAAGC
GTGCTGGTGTTTTTGAACATGCTCATTATCGTGCATGCCTTTTTCCCTATGTTTTCGCCCTACCAGCTCTTTAGCATTCC
TTTAGGCTTGATTTTTATCGTGTTTTTCCCTTTGAGTTTGTTCTTGCATGCGGTGGGTTTGGGGTCTTTATTGGATCATA
TTCTAAGCATGCCTTTAACAATCCCCACGATTTCAATCCCTTCACCCTTATGGCTTTTAGGGGCGCATTTATGTTTAACG
ATTTTAAGCGCGCGTTCTTTTAAAGTTTATTTAAGCATGAATGTTTTAAGCGCGGGCTTTTTCTTGTATTGTTGCTATCA
ATATATTATAATGCCTAGCTTAATTGTAGGTTAG

Domains

Predicted by InterproScan.

Competence protein (Competence)

(159-378)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/comE3 Helicobacter pylori 26695

95.652

100

0.957

Multiple sequence alignment