Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   D4K94_RS07695 Genome accession   NZ_CP032900
Coordinates   1561268..1563631 (-) Length   787 a.a.
NCBI ID   WP_139546593.1    Uniprot ID   -
Organism   Helicobacter pylori strain 476-A-EK5     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1556268..1568631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4K94_RS07670 lpxE 1556793..1557305 (+) 513 WP_236635854.1 lipid A 1-phosphatase LpxE -
  D4K94_RS07675 nspC 1557328..1558545 (-) 1218 WP_139546591.1 carboxynorspermidine decarboxylase -
  D4K94_RS07680 cheV1 1558542..1559507 (-) 966 WP_120802428.1 chemotaxis protein CheV1 -
  D4K94_RS07685 - 1559607..1560947 (-) 1341 WP_201737468.1 COG3014 family protein -
  D4K94_RS07695 comB4 1561268..1563631 (-) 2364 WP_139546593.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  D4K94_RS07700 comB3 1563633..1563896 (-) 264 WP_000584956.1 hypothetical protein Machinery gene
  D4K94_RS07705 comB2 1563896..1564177 (-) 282 WP_101000542.1 TrbC/VirB2 family protein Machinery gene
  D4K94_RS07710 - 1564323..1565150 (-) 828 WP_139542493.1 DUF5718 family protein -
  D4K94_RS07715 - 1565241..1566293 (-) 1053 WP_139542494.1 MnmA/TRMU family protein -
  D4K94_RS07720 dnaG 1566290..1567969 (-) 1680 WP_139542495.1 DNA primase -
  D4K94_RS07730 groES 1568253..1568609 (+) 357 WP_000671934.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90304.64 Da        Isoelectric Point: 7.6698

>NTDB_id=320090 D4K94_RS07695 WP_139546593.1 1561268..1563631(-) (comB4) [Helicobacter pylori strain 476-A-EK5]
MLEKFLGAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDHQQSIQSDSQYLQAILNQFENKEVYENQYFLVLESTHSLQGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFNLPLKPLVGGYLSDSYIASSTTFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSVHKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDTQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIYLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKETARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLAPSRDKEALEDMNAVSCAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLSLSLEPYLNNPLFNALNDALNSNAFLNVINLDTITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHHFNVPLSETEIS
FLENTPLYARQVLVKNLGNGNSNMIDVSLESLGRYLEIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=320090 D4K94_RS07695 WP_139546593.1 1561268..1563631(-) (comB4) [Helicobacter pylori strain 476-A-EK5]
ATGTTAGAAAAGTTTTTAGGCGCTATCAAACAAAAAGTTTCAAATTATTTTTTAGGGGTTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAACATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAAGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCGCGCCTGGTGGTTAAAAGGCGTAAAATTGATCACCAACAAAGCATTCAATCTGATTCTCA
ATACTTGCAAGCGATTTTGAATCAATTTGAAAATAAAGAAGTGTATGAGAATCAGTATTTTTTAGTTTTAGAAAGCACTC
ACTCTTTACAAGGTGTTTTGGAGCATAAGAAAAAATCTCTCATGCATGCCAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCTTAGAAATCCAGCTCAAAAATTATGCCCCCAAACTCTTAAGCTC
CAAAGAGGTTTTGAATTTTTATGCGGAATACATTAATGGGTTTAATCTCCCTTTAAAGCCCTTAGTAGGGGGGTATTTGA
GCGACAGCTATATCGCTAGTTCTACCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAGGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACTCC
ACTAGATATTATCTTTTCCATAGAGCCTATGAGCGTGCATAAAACACTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCTAATCTCGTTAAAAACGAGCTGTTAGAATACCAAGAATTAGTCAAAACCAAACGCCTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCTAGTTTAGAGGATTTAGACACTCAAACTAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCTATTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAACCGCCAGAGTGAATGGGCATACTTTAATCATAGGGGCTACCGGGAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCCTTTGACAGGATGCAAGGGCTG
TATTCTTTCACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATTAACCCCTTTTGTTTAGAGCCTAA
TTTACAGAATCTAGAATTTTTGCAATCCTTCTTTTTGAGTATGTTTGATCTTGCCCCTTCAAGGGATAAAGAAGCCTTGG
AAGATATGAATGCGGTTTCTTGTGCGATTAAGAGCCTTTATGAGACTTTATACCCTAAAGCTTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAACTAAGCTTGAGCTTGGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCACTCAATTCCAACGCTTTTTTAAATGTGATAAACTTAGATACCATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTATTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTACTGAACACTAAAATCAACGCTTTAATCACGCAAGCTAGGAAAGCTAATGG
CGTGGTGGTGTTGGCCTTGCAAGATATTTACCAATTAAGCGGGGTTAAAAACGCTCATAGTTTTTTGAGCAACATGGGGA
CTCTTATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACCATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATTTGGGTAACGGGAATTCTAACATGATTGATGT
GAGTTTGGAAAGTTTGGGGCGTTATTTGGAAATCTTTAATTCGGATTCTAGCCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCCACAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(425-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.078

100

0.971

Multiple sequence alignment