Detailed information    

insolico Bioinformatically predicted

Overview


Name   comB2   Type   Machinery gene
Locus tag   D4L20_RS00400 Genome accession   NZ_CP032899
Coordinates   85767..86051 (+) Length   94 a.a.
NCBI ID   WP_000736106.1    Uniprot ID   T0F3N0
Organism   Helicobacter pylori strain 478-A-EK1     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 80767..91051
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4L20_RS00360 - 80801..81328 (+) 528 WP_000795968.1 LPP20 family lipoprotein -
  D4L20_RS00365 - 81336..81677 (+) 342 WP_139549138.1 hypothetical protein -
  D4L20_RS00370 - 81687..82598 (+) 912 WP_139549139.1 LPP20 family lipoprotein -
  D4L20_RS00375 - 82953..83540 (-) 588 Protein_74 restriction endonuclease subunit S -
  D4L20_RS00380 - 83576..84220 (-) 645 Protein_75 restriction endonuclease subunit M -
  D4L20_RS00385 - 84275..85063 (+) 789 WP_001140574.1 hypothetical protein -
  D4L20_RS00390 - 85066..85254 (+) 189 WP_139549141.1 hypothetical protein -
  D4L20_RS00395 - 85291..85770 (+) 480 WP_139549142.1 hypothetical protein -
  D4L20_RS00400 comB2 85767..86051 (+) 285 WP_000736106.1 TrbC/VirB2 family protein Machinery gene
  D4L20_RS00405 comB3 86063..86326 (+) 264 WP_001177716.1 hypothetical protein Machinery gene
  D4L20_RS00410 - 86338..86571 (+) 234 WP_139549143.1 hypothetical protein -
  D4L20_RS00415 - 86571..89147 (+) 2577 WP_139549144.1 VirB4 family type IV secretion/conjugal transfer ATPase -
  D4L20_RS08155 - 89144..89284 (+) 141 WP_000789929.1 hypothetical protein -
  D4L20_RS00425 - 89277..90413 (+) 1137 WP_139549145.1 VirB8/TrbF family protein -

Sequence


Protein


Download         Length: 94 a.a.        Molecular weight: 10752.11 Da        Isoelectric Point: 11.1589

>NTDB_id=320051 D4L20_RS00400 WP_000736106.1 85767..86051(+) (comB2) [Helicobacter pylori strain 478-A-EK1]
MKKLRHFRKLIAFLGFSPLLLQADMTTFFNSIEQQLTSPTAKGILMVIFLGLAIFIWKNLDRWKEILMTVLAIAIGAAIF
FKAPALANWFMSIF

Nucleotide


Download         Length: 285 bp        

>NTDB_id=320051 D4L20_RS00400 WP_000736106.1 85767..86051(+) (comB2) [Helicobacter pylori strain 478-A-EK1]
ATGAAAAAATTAAGGCATTTTAGAAAGCTTATCGCCTTTTTAGGTTTTTCACCTCTTTTATTACAAGCGGATATGACTAC
CTTTTTTAATTCCATTGAACAACAGCTCACTAGCCCTACGGCTAAAGGCATTTTAATGGTTATTTTTTTAGGACTTGCTA
TTTTTATATGGAAAAACTTAGATAGATGGAAAGAAATTTTAATGACCGTGCTTGCTATTGCAATTGGTGCTGCAATCTTT
TTTAAAGCCCCAGCCTTAGCTAACTGGTTTATGAGTATTTTTTAA

Domains


Predicted by InterproScan.

(4-90)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB T0F3N0

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

57.778

95.745

0.553


Multiple sequence alignment