Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   D9C11_RS17840 Genome accession   NZ_CP032855
Coordinates   3337802..3338458 (+) Length   218 a.a.
NCBI ID   WP_014479448.1    Uniprot ID   A0A165B643
Organism   Bacillus subtilis subsp. subtilis strain PJ-7     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3332802..3343458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D9C11_RS17810 (D9C11_17810) oppF 3333268..3334185 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  D9C11_RS17815 (D9C11_17815) yjbB 3334291..3335508 (+) 1218 WP_121591637.1 MFS transporter -
  D9C11_RS17820 (D9C11_17820) yjbC 3335672..3336250 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  D9C11_RS17825 (D9C11_17825) spx 3336431..3336826 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  D9C11_RS17830 (D9C11_17830) yjbE 3336869..3337525 (-) 657 WP_014479447.1 TerC family protein -
  D9C11_RS17835 (D9C11_17835) - 3337695..3337835 (+) 141 WP_119122854.1 hypothetical protein -
  D9C11_RS17840 (D9C11_17840) mecA 3337802..3338458 (+) 657 WP_014479448.1 adaptor protein MecA Regulator
  D9C11_RS17845 (D9C11_17845) - 3338453..3338575 (-) 123 WP_021479547.1 hypothetical protein -
  D9C11_RS17850 (D9C11_17850) coiA 3338649..3339770 (+) 1122 WP_250622001.1 competence protein CoiA Machinery gene
  D9C11_RS17855 (D9C11_17855) pepF 3340000..3341853 (+) 1854 WP_205589324.1 oligoendopeptidase F -
  D9C11_RS17860 (D9C11_17860) - 3341867..3342034 (-) 168 WP_003244944.1 hypothetical protein -
  D9C11_RS17870 (D9C11_17870) spxH 3342348..3343247 (-) 900 WP_024573348.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25733.66 Da        Isoelectric Point: 4.1174

>NTDB_id=319359 D9C11_RS17840 WP_014479448.1 3337802..3338458(+) (mecA) [Bacillus subtilis subsp. subtilis strain PJ-7]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALEAIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=319359 D9C11_RS17840 WP_014479448.1 3337802..3338458(+) (mecA) [Bacillus subtilis subsp. subtilis strain PJ-7]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTATTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAGCGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A165B643

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995

Multiple sequence alignment