Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ACRYA_RS06245 Genome accession   NZ_CP032823
Coordinates   1243737..1245578 (+) Length   613 a.a.
NCBI ID   WP_105916675.1    Uniprot ID   A0AAD0XAJ1
Organism   Aliarcobacter cryaerophilus ATCC 43158     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1238737..1250578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACRYA_RS06235 (ACRYA_1250) - 1239462..1240499 (+) 1038 WP_105916673.1 efflux RND transporter periplasmic adaptor subunit -
  ACRYA_RS06240 (ACRYA_1251) - 1240502..1243654 (+) 3153 WP_105916674.1 efflux RND transporter permease subunit -
  ACRYA_RS06245 (ACRYA_1252) uvrC 1243737..1245578 (+) 1842 WP_105916675.1 excinuclease ABC subunit UvrC Machinery gene
  ACRYA_RS06250 (ACRYA_1253) - 1245571..1246602 (+) 1032 WP_105916676.1 alanine racemase -
  ACRYA_RS06255 (ACRYA_1254) - 1246632..1247759 (-) 1128 WP_105916677.1 iron-containing alcohol dehydrogenase -
  ACRYA_RS06260 (ACRYA_1255) - 1247798..1248982 (-) 1185 WP_207796766.1 MFS transporter -
  ACRYA_RS10760 - 1248993..1249136 (-) 144 WP_165786073.1 cyclophilin-like fold protein -
  ACRYA_RS06265 - 1249123..1249221 (-) 99 WP_105916678.1 twin-arginine translocation signal domain-containing protein -
  ACRYA_RS06270 (ACRYA_1256) - 1249312..1250214 (-) 903 WP_228199729.1 AraC family transcriptional regulator -

Sequence

Protein


Download         Length: 613 a.a.        Molecular weight: 71248.59 Da        Isoelectric Point: 9.1738

>NTDB_id=319005 ACRYA_RS06245 WP_105916675.1 1243737..1245578(+) (uvrC) [Aliarcobacter cryaerophilus ATCC 43158]
MNLEEKLKELPNDSGVYQYFDENGHLLYIGKAKVLKNRVKSYFKFTPKLLPADKLSPRIYKMISETTFVEWIVVPNEHDA
LILENSLIKQLKPKYNVLLRDDKTYPYIYVDLNEDFPRLEITRKIEKGKNIKYFGPYSSGAKDMLDSIYEIVPLVQKKSC
IKGKSACLFYQIGKCKAPCVGKITKDEYKKLLDEALIYIYNKSKLLSKLKEKMKIYSDDFRFEDALNLRDRVKTIEKSQI
KTGIDLATNEDLDIFAIKSGSKKAVIVRMFIRDGKLASSNYDFIKINDDLEFDLYEAYKRAIVNYYTNELPIIPKEIILA
DEILDLDDIEEFLYKRFNKKIKLINPKIDKKASIVKIALSNCDELLRVEASKNQTTIYEELKELFCLQTTPSLIESFDNS
HLMGQATVGAMIVWNEDLGSFDKKSFRHYNLESKDEYSQMREMLMRRVESFSKNPAPDLWIIDGGETLLKLAFDIVQSIG
VNLDIIAISKQKVDAKAYRAKGNARDIVHFKENGEYKSLNLLPSDKRLQFVQRQRDEAHRFAISFHKKKKRKEDKEISFL
QISGIGEAKIKKLLLYFGEFEKIKSASLEELKTVLNEVDSKNIFDYFKKEENG

Nucleotide


Download         Length: 1842 bp        

>NTDB_id=319005 ACRYA_RS06245 WP_105916675.1 1243737..1245578(+) (uvrC) [Aliarcobacter cryaerophilus ATCC 43158]
ATGAATTTAGAAGAGAAATTAAAAGAGTTACCAAATGATTCTGGAGTTTATCAATACTTTGATGAAAACGGTCATCTACT
ATATATTGGAAAAGCAAAAGTTTTAAAAAATAGAGTAAAATCTTATTTTAAATTTACTCCAAAACTCCTACCTGCTGATA
AACTAAGCCCACGAATATATAAAATGATTAGTGAAACTACTTTTGTAGAGTGGATTGTTGTTCCAAATGAACATGATGCT
TTAATACTTGAAAACTCTTTAATCAAACAGCTAAAACCAAAATACAATGTACTTTTAAGAGATGATAAAACCTATCCATA
TATTTATGTTGATTTAAACGAAGATTTTCCAAGACTTGAAATTACAAGAAAAATAGAAAAAGGTAAAAATATAAAATATT
TTGGTCCTTACTCAAGTGGTGCAAAAGATATGTTAGATAGCATATATGAAATAGTTCCATTGGTGCAAAAAAAATCTTGT
ATAAAAGGAAAGAGTGCTTGTCTATTTTATCAAATAGGAAAATGTAAAGCTCCATGTGTTGGAAAAATAACAAAAGATGA
GTATAAAAAACTTCTAGATGAAGCTTTAATATATATATACAATAAATCAAAACTTTTATCAAAACTAAAAGAGAAAATGA
AAATATATTCAGATGATTTCCGTTTTGAAGATGCTTTAAATTTAAGAGATAGAGTAAAAACTATTGAAAAATCGCAAATC
AAAACAGGTATAGATTTAGCAACAAATGAAGATTTGGATATATTTGCTATAAAATCTGGTAGTAAAAAAGCTGTAATTGT
AAGAATGTTTATAAGAGATGGAAAACTTGCATCTTCAAATTATGATTTTATAAAAATAAATGATGATTTAGAGTTTGATT
TATATGAAGCCTACAAAAGAGCTATTGTAAACTACTACACAAATGAGCTTCCAATTATCCCAAAAGAGATTATTTTAGCT
GATGAAATTTTAGATTTAGATGATATTGAAGAGTTTTTATATAAGAGATTTAATAAAAAGATAAAATTAATAAATCCAAA
AATAGACAAAAAAGCTAGTATTGTAAAAATTGCATTAAGTAACTGTGATGAACTTCTAAGAGTTGAAGCTTCAAAAAATC
AAACAACTATATATGAAGAGTTAAAAGAACTATTTTGCCTACAAACAACTCCTAGCTTAATAGAAAGTTTTGACAACTCT
CACTTAATGGGACAAGCAACAGTTGGAGCTATGATTGTTTGGAATGAAGATTTAGGCTCTTTTGACAAAAAATCTTTTAG
ACACTATAACCTTGAATCAAAAGATGAATACTCACAAATGAGAGAGATGTTAATGAGAAGAGTTGAGAGCTTTTCAAAGA
ATCCAGCTCCTGATTTATGGATTATAGATGGTGGAGAAACTTTGCTAAAACTAGCTTTTGATATTGTGCAAAGTATTGGG
GTAAATTTGGATATTATTGCGATTTCAAAGCAAAAAGTAGATGCCAAAGCCTATAGAGCAAAAGGTAATGCAAGAGATAT
AGTCCATTTTAAGGAAAATGGTGAATACAAAAGCTTAAATCTTCTTCCAAGTGATAAAAGATTACAGTTTGTACAAAGAC
AAAGAGATGAAGCACATAGATTTGCTATTAGTTTTCACAAAAAGAAAAAAAGAAAAGAGGATAAAGAGATTTCCTTTTTA
CAAATAAGCGGAATAGGTGAAGCTAAAATAAAAAAACTTCTTCTATATTTTGGTGAGTTTGAAAAAATAAAAAGTGCAAG
TTTAGAAGAGTTAAAAACTGTTTTAAACGAAGTTGATTCAAAAAATATATTTGATTATTTTAAAAAGGAAGAAAATGGCT
AG

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(383-543)

UvrB/uvrC motif (UVR)

(204-237)

GIY-YIG catalytic domain (GIY-YIG)

(15-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.51

97.227

0.501

Multiple sequence alignment