Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   D5S13_RS09915 Genome accession   NZ_CP032821
Coordinates   2015938..2016654 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain JDFM SA01     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2010938..2021654
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D5S13_RS09895 (D5S13_01893) - 2012030..2012980 (+) 951 WP_029625646.1 LacI family DNA-binding transcriptional regulator -
  D5S13_RS09900 (D5S13_01894) - 2013129..2014613 (+) 1485 WP_263258447.1 sucrose-6-phosphate hydrolase -
  D5S13_RS09905 (D5S13_01895) - 2014610..2015569 (+) 960 WP_001253302.1 carbohydrate kinase family protein -
  D5S13_RS09910 - 2015757..2015866 (-) 110 Protein_1940 hypothetical protein -
  D5S13_RS09915 (D5S13_01896) agrA 2015938..2016654 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  D5S13_RS09920 (D5S13_01897) agrC 2016673..2017966 (-) 1294 Protein_1942 quorum-sensing sensor histidine kinase AgrC -
  D5S13_RS09925 (D5S13_01899) agrD 2017991..2018131 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  D5S13_RS09930 (D5S13_01900) agrB 2018128..2018697 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  D5S13_RS09935 hld 2018987..2019067 (+) 81 WP_000046022.1 delta-hemolysin -
  D5S13_RS09940 (D5S13_01902) - 2019667..2020452 (-) 786 WP_000867939.1 carbon-nitrogen family hydrolase -
  D5S13_RS09945 (D5S13_01903) - 2020813..2021439 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=318980 D5S13_RS09915 WP_000688498.1 2015938..2016654(-) (agrA) [Staphylococcus aureus strain JDFM SA01]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=318980 D5S13_RS09915 WP_000688498.1 2015938..2016654(-) (agrA) [Staphylococcus aureus strain JDFM SA01]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment