Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   CBUK_RS10365 Genome accession   NC_011528
Coordinates   1967282..1968208 (+) Length   308 a.a.
NCBI ID   WP_012570936.1    Uniprot ID   -
Organism   Coxiella burnetii CbuK_Q154     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1962282..1973208
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CBUK_RS10325 (CbuK_2040) - 1962874..1963146 (-) 273 WP_005768315.1 hypothetical protein -
  CBUK_RS13165 - 1963147..1963284 (+) 138 WP_230579817.1 hypothetical protein -
  CBUK_RS10330 (CbuK_2041) - 1963337..1963591 (+) 255 WP_005769716.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
  CBUK_RS10335 (CbuK_2042) - 1963591..1963866 (+) 276 WP_005769718.1 Txe/YoeB family addiction module toxin -
  CBUK_RS10340 (CbuK_2043) - 1963839..1964324 (-) 486 WP_005769725.1 dihydrofolate reductase -
  CBUK_RS10345 (CbuK_2044) - 1964321..1965124 (-) 804 WP_012570935.1 epoxyqueuosine reductase QueH -
  CBUK_RS10350 (CbuK_2045) - 1965320..1965607 (+) 288 WP_005769730.1 acylphosphatase -
  CBUK_RS10355 (CbuK_2046) gmhB 1965583..1966137 (-) 555 WP_005769732.1 D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase -
  CBUK_RS10360 (CbuK_2047) fmt 1966150..1967094 (-) 945 WP_005769734.1 methionyl-tRNA formyltransferase -
  CBUK_RS10365 (CbuK_2048) dprA 1967282..1968208 (+) 927 WP_012570936.1 DNA-processing protein DprA Machinery gene
  CBUK_RS10370 (CbuK_2049) - 1968205..1968684 (+) 480 WP_011997413.1 DUF494 domain-containing protein -
  CBUK_RS10375 (CbuK_2050) topA 1968687..1970984 (+) 2298 WP_005769743.1 type I DNA topoisomerase -
  CBUK_RS10380 (CbuK_2051) - 1970991..1971161 (-) 171 WP_010958590.1 hypothetical protein -
  CBUK_RS10385 (CbuK_2052) purE 1971192..1971692 (+) 501 WP_005769750.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  CBUK_RS10390 (CbuK_2053) - 1971695..1972255 (+) 561 WP_005769752.1 L-threonylcarbamoyladenylate synthase -
  CBUK_RS13170 - 1972305..1972424 (+) 120 Protein_2116 hypothetical protein -
  CBUK_RS10395 (CbuK_2054) - 1972698..1972838 (+) 141 WP_010958591.1 hypothetical protein -

Sequence

Protein


Download         Length: 308 a.a.        Molecular weight: 32996.23 Da        Isoelectric Point: 7.8924

>NTDB_id=31787 CBUK_RS10365 WP_012570936.1 1967282..1968208(+) (dprA) [Coxiella burnetii CbuK_Q154]
MQPPFNALLFFAMPNSQLDPEWTTAPNHHILTLDHPSYPTLLKEIPDPPKKLYIMGDPLILNQPQFAIVGSRNPTVTGCE
IAQEMAEKLVQAGFHITSGLALGIDAASHRGALKAGGKTIAVLGSGLTNIYPRRHHRLAEQISQKGALVSEFPLTMPPLP
TNFPRRNRIISGLSLGTLVVEATLGSGSLITAKLAAEQNREVFAIPGSIRNPLSQGCHALIKEGAKLVDSIGDIIAELSY
EATGASAPIQALDKNEHKLLECIGFEVTSIDQLIARSGFSASIVASLLLRIELQGYIKSTPGGVIRVK

Nucleotide


Download         Length: 927 bp        

>NTDB_id=31787 CBUK_RS10365 WP_012570936.1 1967282..1968208(+) (dprA) [Coxiella burnetii CbuK_Q154]
TTGCAACCTCCCTTCAATGCACTATTATTTTTCGCCATGCCAAATTCTCAATTAGACCCAGAATGGACGACAGCGCCGAA
CCACCATATTTTGACGCTCGATCATCCCTCCTACCCTACTTTATTGAAGGAAATCCCCGATCCGCCCAAAAAGCTCTACA
TCATGGGTGACCCTTTGATATTAAATCAGCCGCAATTTGCCATCGTCGGCAGCCGTAATCCAACCGTCACCGGCTGCGAA
ATCGCACAAGAAATGGCAGAGAAACTCGTTCAAGCTGGTTTTCACATCACCAGCGGCCTTGCACTTGGCATCGATGCCGC
AAGTCACCGCGGGGCTTTAAAAGCAGGAGGCAAAACCATAGCCGTACTCGGCAGCGGCTTAACTAACATATATCCTCGAC
GCCACCACCGTCTGGCGGAACAAATTTCCCAAAAAGGCGCCCTCGTCTCAGAATTCCCGCTAACCATGCCGCCACTCCCC
ACCAACTTCCCTCGCCGCAACCGCATCATCAGCGGATTAAGCCTCGGTACGCTCGTGGTGGAAGCTACCCTTGGCTCAGG
CTCTCTGATCACCGCGAAATTAGCCGCCGAACAAAACCGGGAAGTTTTCGCCATCCCGGGTTCAATCCGAAACCCTCTTT
CTCAGGGATGCCATGCTCTCATCAAAGAGGGCGCTAAACTGGTTGATTCTATAGGGGATATTATTGCAGAATTGAGTTAT
GAGGCTACGGGTGCTAGCGCCCCGATTCAAGCACTTGATAAGAATGAACACAAACTGTTAGAGTGCATCGGATTTGAGGT
CACTTCCATTGATCAACTGATCGCTCGAAGTGGCTTTTCGGCTTCCATCGTAGCTTCGTTATTGTTAAGGATAGAATTGC
AAGGCTACATTAAATCAACACCTGGCGGTGTTATACGAGTGAAGTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(25-229)

DprA winged helix domain (DprA_WH)

(245-303)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Legionella pneumophila strain ERS1305867

54.949

95.13

0.523
  dprA Vibrio campbellii strain DS40M4

48.039

99.351

0.477
  dprA Vibrio cholerae strain A1552

48.829

97.078

0.474
  dprA Glaesserella parasuis strain SC1401

45.277

99.675

0.451
  dprA Acinetobacter baumannii D1279779

44.71

95.13

0.425
  dprA Acinetobacter baumannii strain A118

44.218

95.455

0.422
  dprA Acinetobacter baylyi ADP1

43.289

96.753

0.419
  dprA Haemophilus influenzae Rd KW20

55.046

70.779

0.39

Multiple sequence alignment