Detailed information NTG0317752

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: MGAS27961_RS03205
• Genome accession: NZ_CP032665
• Coordinates: 623028..624065 (+)
• Length: 345 a.a.
• NCBI ID: WP_011284961.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS27961
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 618028..629065

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS27961_RS03180 (MGAS27961_03180)	-	618292..619623 (+)	1332	WP_011284962.1	dipeptidase	-
MGAS27961_RS03185 (MGAS27961_03185)	arcC	619643..620593 (+)	951	WP_009880962.1	carbamate kinase	-
MGAS27961_RS03190 (MGAS27961_03190)	asnA	620906..621898 (+)	993	WP_002983817.1	aspartate--ammonia ligase	-
MGAS27961_RS03195 (MGAS27961_03195)	rsmD	622021..622560 (+)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
MGAS27961_RS03200 (MGAS27961_03200)	coaD	622550..623041 (+)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
MGAS27961_RS03205 (MGAS27961_03205)	sepM	623028..624065 (+)	1038	WP_011284961.1	SepM family pheromone-processing serine protease	Regulator
MGAS27961_RS03210 (MGAS27961_03210)	-	624480..625457 (+)	978	WP_021341005.1	LacI family DNA-binding transcriptional regulator	-
MGAS27961_RS03215 (MGAS27961_03215)	-	625905..626525 (+)	621	WP_002992791.1	YutD family protein	-
MGAS27961_RS03220 (MGAS27961_03220)	rlmN	626529..627608 (+)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
MGAS27961_RS03225 (MGAS27961_03225)	-	627690..628316 (-)	627	WP_002983834.1	A24 family peptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.27 Da
• Isoelectric Point: 9.6692

>NTDB_id=317752 MGAS27961_RS03205 WP_011284961.1 623028..624065(+) (sepM) [Streptococcus pyogenes strain MGAS27961]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDTDFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=317752 MGAS27961_RS03205 WP_011284961.1 623028..624065(+) (sepM) [Streptococcus pyogenes strain MGAS27961]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCGCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATACTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69