Detailed information NTG0317747

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: MGAS27961_RS02195
• Genome accession: NZ_CP032665
• Coordinates: 419586..420311 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain MGAS27961
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 414586..425311

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS27961_RS02165 (MGAS27961_02165)	-	414765..416225 (+)	1461	WP_002988645.1	NCS2 family permease	-
MGAS27961_RS02170 (MGAS27961_02170)	tsaE	416379..416840 (+)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
MGAS27961_RS02175 (MGAS27961_02175)	-	416815..417339 (+)	525	WP_011285082.1	GNAT family N-acetyltransferase	-
MGAS27961_RS02180 (MGAS27961_02180)	-	417348..418631 (+)	1284	WP_002983372.1	biofilm formation/cell division transcriptional regulator BrpA	-
MGAS27961_RS02185 (MGAS27961_02185)	-	418742..419098 (-)	357	WP_002988657.1	hypothetical protein	-
MGAS27961_RS02190 (MGAS27961_02190)	-	419095..419514 (-)	420	WP_011285081.1	HIT family protein	-
MGAS27961_RS02195 (MGAS27961_02195)	pptA	419586..420311 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
MGAS27961_RS02200 (MGAS27961_02200)	-	420314..421348 (+)	1035	WP_011285080.1	ABC transporter permease	-
MGAS27961_RS02205 (MGAS27961_02205)	ccrZ	421412..422203 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
MGAS27961_RS02210 (MGAS27961_02210)	trmB	422203..422838 (+)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
MGAS27961_RS02220 (MGAS27961_02220)	rimP	423097..423633 (+)	537	WP_002988815.1	ribosome maturation factor RimP	-
MGAS27961_RS02225 (MGAS27961_02225)	nusA	423808..424965 (+)	1158	WP_002983485.1	transcription termination factor NusA	-
MGAS27961_RS02230 (MGAS27961_02230)	rnpM	424981..425277 (+)	297	WP_002983486.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=317747 MGAS27961_RS02195 WP_002983379.1 419586..420311(+) (pptA) [Streptococcus pyogenes strain MGAS27961]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=317747 MGAS27961_RS02195 WP_002983379.1 419586..420311(+) (pptA) [Streptococcus pyogenes strain MGAS27961]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGATAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714