Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   D7D53_RS02365 Genome accession   NZ_CP032621
Coordinates   490884..493145 (-) Length   753 a.a.
NCBI ID   WP_120770002.1    Uniprot ID   A0A387B286
Organism   Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 485884..498145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D53_RS02335 (D7D53_02335) metK 486238..487428 (+) 1191 WP_004259911.1 methionine adenosyltransferase -
  D7D53_RS02340 (D7D53_02340) - 487512..488147 (-) 636 WP_120769998.1 GNAT family N-acetyltransferase -
  D7D53_RS02345 (D7D53_02345) - 488280..488579 (-) 300 WP_000767189.1 DUF1827 family protein -
  D7D53_RS02350 (D7D53_02350) - 488638..489090 (-) 453 WP_120769999.1 NUDIX hydrolase -
  D7D53_RS02355 (D7D53_02355) - 489266..490168 (+) 903 WP_120770000.1 helix-turn-helix transcriptional regulator -
  D7D53_RS02360 (D7D53_02360) - 490223..490837 (+) 615 WP_120770001.1 GyrI-like domain-containing protein -
  D7D53_RS02365 (D7D53_02365) clpE 490884..493145 (-) 2262 WP_120770002.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  D7D53_RS02370 (D7D53_02370) - 493375..493605 (-) 231 WP_000443570.1 DUF1797 family protein -
  D7D53_RS02375 (D7D53_02375) - 493796..494479 (+) 684 WP_033686685.1 amino acid ABC transporter permease -
  D7D53_RS02380 (D7D53_02380) - 494479..495213 (+) 735 WP_120770003.1 amino acid ABC transporter ATP-binding protein -
  D7D53_RS02390 (D7D53_02390) - 495588..496151 (+) 564 WP_049552627.1 HAD family hydrolase -
  D7D53_RS02395 (D7D53_02395) gyrB 496166..498112 (+) 1947 WP_049487808.1 DNA topoisomerase (ATP-hydrolyzing) subunit B -

Sequence

Protein


Download         Length: 753 a.a.        Molecular weight: 83931.42 Da        Isoelectric Point: 5.4579

>NTDB_id=317178 D7D53_RS02365 WP_120770002.1 490884..493145(-) (clpE) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSLFKGMTDLNNRDFDPFGDFFNDLNNFRPSNNTPPTPP
TQSGGGYGGNGGYGSQNRGPAQTPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSA
GDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVQYTDAA
IEAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRDQIAKYKEM
QKKKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKSHVIGQDDAVDKIAKAIRRNRVGLGTPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLENP
SEKDLKAVMTSKGKIQIKSAKKAEKIKENTSEK

Nucleotide


Download         Length: 2262 bp        

>NTDB_id=317178 D7D53_RS02365 WP_120770002.1 490884..493145(-) (clpE) [Streptococcus gwangjuensis strain KCOM 1679 (=ChDC B345)]
ATGCTTTGTCAAAACTGTAAAATCAATGACTCAACAATTCATCTTTATACCAATCTTAACGGAAAGCAAAAACAAATTGA
CCTTTGTCAAAACTGCTATAAGATTATCAAGACGGATCCTAACAATAGCCTCTTTAAAGGTATGACGGATCTGAACAATC
GTGACTTTGATCCCTTTGGTGATTTCTTCAATGACCTAAACAATTTTAGACCTTCTAACAACACTCCTCCGACTCCCCCA
ACCCAATCAGGTGGAGGTTACGGTGGAAACGGCGGTTATGGTTCCCAAAATCGTGGACCTGCTCAAACTCCTCCACCAAG
CCAAGAAAAAGGCCTGCTGGAAGAATTTGGTATCAACGTAACTGAAATTGCCCGTCGTGGAGATATAGATCCCGTTATTG
GACGCGATGATGAGATTATCCGTGTCATTGAGATTCTCAATCGCAGAACCAAGAATAATCCTGTTCTTATCGGTGAACCA
GGTGTCGGGAAAACTGCCGTTGTCGAAGGTCTAGCTCAGAAAATCGTTGATGGCGATGTTCCACATAAACTACAAGGTAA
ACAAGTCATCCGTCTGGATGTGGTTAGCCTAGTTCAAGGAACGGGTATTCGTGGACAATTTGAAGAACGCATGCAAAAGC
TCATGGAAGAAATTCGCAAACGTGAGGATATTATCCTCTTTATCGATGAAATCCATGAAATTGTCGGTGCGGGATCTGCG
GGCGATGGCAATATGGATGCAGGAAATATCCTCAAGCCAGCCCTTGCTCGTGGTGAACTGCAACTGGTCGGTGCAACTAC
CCTCAATGAATACCGCATCATTGAAAAAGATGCTGCCCTAGAACGCCGTATGCAGCCTGTTAAGGTCGATGAACCAACGG
TAGAAGAAACAATCACTATCCTCAAAGGCATTCAAAAGAAATACGAAGACTACCACCATGTTCAGTATACTGATGCTGCG
ATTGAAGCAGCTGCAACTCTGTCCAATCGCTACATCCAAGATCGCTTCTTGCCTGACAAGGCCATTGACCTCCTAGATGA
AGCTGGTTCTAAGATGAACTTGACCTTGAATTTTGTTGATCCTAAAGTAATTGATCAACGCTTGATTGAGGCTGAAAATC
TCAAATCTCAAGCTACACGAGAGGAAGATTTTGAGAAGGCAGCTTATTTCCGCGACCAGATTGCCAAGTATAAGGAAATG
CAAAAGAAAAAGGTCACAGACCAAGATACTCCTATCATCAGTGAGAAAACCATTGAGCACATTATCGAGCAGAAAACCAA
TATCCCTGTTGGTGATTTAAAAGAGAAAGAACAATCTCAACTCATCCATCTAGCCGAAGATCTCAAGTCTCATGTTATTG
GCCAAGATGATGCGGTTGATAAGATTGCCAAAGCTATTCGCCGTAATCGTGTTGGACTCGGTACGCCTAACCGTCCTATT
GGAAGCTTCCTCTTTGTTGGGCCAACTGGTGTCGGTAAGACGGAACTTTCCAAACAACTAGCTATCGAACTCTTTGGTTC
TGCTGACAGTATGATTCGCTTTGATATGAGTGAATATATGGAAAAACACAGCGTGGCTAAATTGGTCGGTGCCCCTCCAG
GTTATGTTGGCTATGATGAGGCTGGGCAATTAACGGAAAAAGTTCGTCGCAATCCATATTCACTTATTCTCTTGGATGAA
GTAGAGAAAGCCCATCCAGATGTTATGCACATGTTCCTTCAAGTCTTGGACGATGGTCGTTTGACAGATGGACAAGGACG
TACCGTTAGTTTCAAGGATGCCATCATCATCATGACTTCAAATGCAGGTACAGGTAAGGCCGAAGCCAGCGTTGGATTTG
GGGCTGCTAGAGAAGGACGTACCAACTCTGTTCTCGGTGAACTCGGTAACTTCTTTAGCCCAGAGTTTATGAACCGTTTT
GATGGTATTATCGAATTTAAGGCTCTCAGCAAGGATAACCTCCTTCAGATTGTCGAGCTGATGCTAGCAGACGTTAACAA
GCGCCTTTCTAGCAATAACATTCATTTGGATGTAACTGACAAGGTCAAGGAAAAATTGGTTGACCTAGGCTATGATCCAA
AAATGGGAGCACGCCCACTTCGTCGTACTATTCAAGACTATATTGAGGATGCCATCACTGACTACTACCTTGAAAATCCA
AGTGAAAAAGACCTCAAGGCAGTTATGACCAGCAAGGGCAAGATTCAAATTAAGTCTGCCAAAAAAGCTGAAAAAATCAA
AGAAAATACTTCTGAAAAATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(649-723)

AAA lid domain (AAA_lid_9)

(293-390)

ATPase family associated with various cellular activities (AAA) (AAA)

(155-274)

AAA domain (Cdc48 subfamily) (AAA_2)

(478-641)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A387B286

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

97.742

100

0.977
  clpE Streptococcus pneumoniae D39

97.742

100

0.977
  clpE Streptococcus pneumoniae R6

97.742

100

0.977
  clpE Streptococcus pneumoniae TIGR4

97.61

100

0.976
  clpE Streptococcus mutans UA159

83.046

100

0.833
  clpC Lactococcus lactis subsp. cremoris KW2

77.384

97.477

0.754
  clpC Bacillus subtilis subsp. subtilis str. 168

50.502

92.563

0.467
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.847

83.267

0.398
  clpC Streptococcus pneumoniae TIGR4

47.293

83.4

0.394
  clpC Streptococcus pneumoniae Rx1

46.91

83.798

0.393
  clpC Streptococcus pneumoniae D39

46.91

83.798

0.393
  clpC Streptococcus mutans UA159

46.89

83.267

0.39
  clpC Streptococcus thermophilus LMD-9

46.795

82.869

0.388
  clpC Streptococcus thermophilus LMG 18311

46.4

83.001

0.385

Multiple sequence alignment