Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   D7D50_RS00095 Genome accession   NZ_CP032620
Coordinates   13945..16212 (+) Length   755 a.a.
NCBI ID   WP_120701159.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 8945..21212
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS00065 (D7D50_00065) xseA 9042..10382 (-) 1341 WP_006596770.1 exodeoxyribonuclease VII large subunit -
  D7D50_RS00070 (D7D50_00070) - 10507..11349 (-) 843 WP_120701156.1 NAD(P)H-hydrate dehydratase -
  D7D50_RS00075 (D7D50_00075) - 11353..12177 (-) 825 WP_120701157.1 phosphate ABC transporter ATPase -
  D7D50_RS00080 (D7D50_00080) - 12317..13174 (-) 858 WP_162614517.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  D7D50_RS00090 (D7D50_00090) - 13485..13715 (-) 231 WP_048687767.1 DUF1797 family protein -
  D7D50_RS00095 (D7D50_00095) clpE 13945..16212 (+) 2268 WP_120701159.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  D7D50_RS00105 (D7D50_00105) - 16473..16922 (+) 450 WP_023022485.1 NUDIX hydrolase -
  D7D50_RS00110 (D7D50_00110) - 16990..17292 (+) 303 WP_006596776.1 DUF1827 family protein -
  D7D50_RS00115 (D7D50_00115) - 17376..17810 (-) 435 WP_023022484.1 GNAT family N-acetyltransferase -
  D7D50_RS00120 (D7D50_00120) ileS 18026..20818 (-) 2793 WP_023022482.1 isoleucine--tRNA ligase -

Sequence

Protein


Download         Length: 755 a.a.        Molecular weight: 83935.00 Da        Isoelectric Point: 4.9018

>NTDB_id=317099 D7D50_RS00095 WP_120701159.1 13945..16212(+) (clpE) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MLCQNCKINDSTIHLYTNVNGHQQQVDLCQNCYQIMKTDPNNSLLAGLNQQNRGGRDPFEDFFNQLGNFQAPQEPQTPPT
QSGGGYGGGNGYGQNGNGRATGPNRPQAKQQPKGLLEEFGINVTEIARRGDIDPVIGRDGEILRVIEILNRRTKNNPVLI
GEPGVGKTAVVEGLAQKIVDGDVPYKLQDKEVIRLDVVSLVQGTGIRGQFEERMQQLMEEIRRREDVILFIDEIHEIVGA
GSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVHYT
DGAIEAAALLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKY
KEMQGQQVTDQDTPVISEKTIEHIVEQKTNIPVGDLKEKEQSQLINLAADLKAHVIGQDEAVEKIAKAIRRNRVGLGTPN
RPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLIL
LDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEANVGFGAAREGRTNSVLGELGNFFSPEFM
NRFDGIIEFQPLSKENLLQIVTLMLDEVNQRLAQNEIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYL
ENPNEKQLKAVMTSNGNISIKGKTKPANEAEKVTE

Nucleotide


Download         Length: 2268 bp        

>NTDB_id=317099 D7D50_RS00095 WP_120701159.1 13945..16212(+) (clpE) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGCTTTGTCAAAACTGTAAAATAAACGATTCAACCATTCATCTTTATACGAATGTGAATGGTCACCAACAACAAGTAGA
CCTTTGCCAGAACTGCTATCAAATTATGAAAACCGATCCTAACAATAGTCTCCTGGCAGGATTAAACCAACAAAATCGCG
GAGGGCGGGATCCTTTTGAAGATTTCTTCAATCAACTGGGCAACTTCCAAGCTCCCCAAGAACCTCAAACGCCACCGACC
CAATCAGGAGGAGGATATGGAGGTGGAAATGGCTACGGACAAAATGGGAACGGTCGAGCTACTGGACCAAATAGACCTCA
AGCCAAACAACAACCAAAAGGACTCCTAGAAGAGTTTGGAATTAATGTTACTGAAATCGCTCGCCGTGGGGACATTGATC
CAGTCATTGGCCGTGACGGCGAAATTCTCCGAGTTATTGAAATTTTAAACCGCCGAACCAAAAACAACCCTGTTCTGATT
GGAGAACCTGGTGTCGGAAAAACAGCTGTCGTAGAGGGCCTGGCCCAGAAGATTGTCGATGGCGATGTCCCTTATAAATT
ACAAGACAAGGAAGTTATTCGGTTAGACGTTGTTAGCCTGGTTCAAGGGACTGGGATTCGTGGACAATTTGAAGAACGGA
TGCAACAACTAATGGAAGAAATCCGTCGCCGTGAAGATGTCATTTTGTTTATCGATGAAATCCATGAAATTGTAGGAGCA
GGATCTGCAGGTGATGGCAACATGGATGCAGGAAATATCCTCAAACCGGCTCTCGCTCGTGGTGAATTGCAATTAGTTGG
TGCCACAACACTCAATGAGTATCGTATTATCGAAAAAGATGCTGCTCTTGAACGCCGGATGCAACCAGTCAAGGTGGATG
AACCAACGGTTGAAGAAACCATTACCATCCTTAAAGGCATTCAAAAGAAATACGAAGACTACCACCACGTCCACTACACA
GATGGTGCTATTGAGGCTGCAGCTCTCCTCTCCAATCGCTATATCCAAGACCGCTTCTTGCCCGACAAAGCCATTGACCT
CTTGGACGAAGCAGGCTCTAAGATGAATTTGACCCTCAATTTTGTCGATCCCAAAGTCATTGACCAGCGCTTAATTGAAG
CCGAAAATCTCAAGGCCCAAGCGACGCGGGATGAAGATTTTGAAAAAGCAGCCTACTTCCGTGACCAAATCGCTAAGTAC
AAAGAAATGCAAGGGCAACAGGTCACCGACCAAGATACGCCCGTCATTAGCGAAAAGACTATCGAACACATTGTTGAGCA
AAAGACCAATATTCCAGTTGGAGATTTGAAAGAAAAAGAACAGTCTCAATTGATTAATTTGGCTGCTGATTTAAAAGCTC
ATGTCATCGGCCAAGATGAGGCTGTTGAAAAAATTGCTAAGGCTATCCGTCGTAATCGGGTAGGACTTGGAACGCCAAAC
CGTCCAATCGGTAGCTTCCTCTTTGTTGGACCAACTGGTGTCGGGAAGACCGAGTTGTCCAAGCAATTGGCCATCGAACT
CTTCGGTTCTGCTGATAGTATGATTCGCTTTGACATGAGTGAATACATGGAGAAACATGCCGTTGCCAAATTGGTCGGTG
CTCCTCCAGGTTATGTCGGCTATGAAGAAGCTGGCCAGCTGACTGAAAAAGTACGTCGCAACCCTTACTCTCTTATTCTT
CTAGATGAGGTAGAAAAGGCCCATCCTGATGTCATGCATATGTTCCTTCAAGTCTTAGATGATGGTCGCTTGACAGATGG
TCAAGGCCGTACCGTTAGCTTTAAAGATACGATTATCATCATGACCTCTAATGCTGGAACTGGCAAAGCGGAGGCCAATG
TTGGCTTTGGAGCAGCTCGTGAAGGTCGCACCAACTCTGTACTTGGAGAACTCGGGAACTTCTTTAGCCCTGAATTCATG
AACCGTTTTGATGGCATCATTGAATTCCAACCTCTCTCAAAAGAAAACCTGCTTCAAATCGTTACTCTCATGCTGGATGA
AGTCAATCAACGTCTCGCACAAAATGAGATTCATCTGGATGTGACAGAGAAGGTGAAAGAAAAATTGGTCGATCTGGGAT
ACGATCCAAAAATGGGGGCCCGCCCACTCCGTCGTACCATTCAAGACTATATTGAAGATGCGATTACCGATTACTACCTT
GAAAATCCAAATGAAAAACAACTCAAGGCAGTCATGACCAGCAATGGAAATATTAGCATTAAAGGAAAGACCAAACCTGC
AAACGAGGCAGAAAAAGTAACTGAATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(652-725)

AAA lid domain (AAA_lid_9)

(296-393)

ATPase family associated with various cellular activities (AAA) (AAA)

(158-277)

AAA domain (Cdc48 subfamily) (AAA_2)

(481-644)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

86.376

100

0.865
  clpE Streptococcus pneumoniae D39

86.376

100

0.865
  clpE Streptococcus pneumoniae R6

86.376

100

0.865
  clpE Streptococcus pneumoniae TIGR4

86.376

100

0.865
  clpE Streptococcus mutans UA159

83.926

100

0.844
  clpC Lactococcus lactis subsp. cremoris KW2

76.455

100

0.766
  clpC Bacillus subtilis subsp. subtilis str. 168

50.661

90.199

0.457
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.325

83.046

0.401
  clpC Streptococcus pneumoniae Rx1

48.387

82.119

0.397
  clpC Streptococcus pneumoniae D39

48.387

82.119

0.397
  clpC Streptococcus pneumoniae TIGR4

48.226

82.119

0.396
  clpC Streptococcus thermophilus LMD-9

46.479

84.636

0.393
  clpC Streptococcus thermophilus LMG 18311

46.311

84.371

0.391
  clpC Streptococcus mutans UA159

47.504

82.252

0.391

Multiple sequence alignment