Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   E5N77_RS35785 Genome accession   NZ_CP039123
Coordinates   8006849..8007487 (-) Length   212 a.a.
NCBI ID   WP_086878669.1    Uniprot ID   -
Organism   Streptomyces sp. SS52     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 8001849..8012487
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E5N77_RS35755 (E5N77_35755) - 8002160..8003422 (+) 1263 WP_127438626.1 cation:proton antiporter -
  E5N77_RS35760 (E5N77_35760) - 8003798..8004268 (-) 471 WP_136236887.1 nuclear transport factor 2 family protein -
  E5N77_RS35765 (E5N77_35765) - 8004412..8004855 (+) 444 WP_168723789.1 Rrf2 family transcriptional regulator -
  E5N77_RS35770 (E5N77_35770) - 8005039..8005938 (-) 900 WP_247608173.1 ferric reductase-like transmembrane domain-containing protein -
  E5N77_RS37905 - 8006401..8006721 (-) 321 WP_234331651.1 hypothetical protein -
  E5N77_RS35785 (E5N77_35785) vraR 8006849..8007487 (-) 639 WP_086878669.1 response regulator transcription factor Regulator
  E5N77_RS35790 (E5N77_35790) - 8007484..8008704 (-) 1221 WP_136236889.1 sensor histidine kinase -
  E5N77_RS35795 (E5N77_35795) - 8008878..8009966 (+) 1089 WP_136236890.1 ABC transporter permease -
  E5N77_RS35800 (E5N77_35800) - 8009963..8010646 (+) 684 WP_136236891.1 ABC transporter ATP-binding protein -
  E5N77_RS35805 (E5N77_35805) - 8011210..8012082 (-) 873 WP_136236892.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 22124.24 Da        Isoelectric Point: 4.7801

>NTDB_id=316849 E5N77_RS35785 WP_086878669.1 8006849..8007487(-) (vraR) [Streptomyces sp. SS52]
MTDDTPIRLLLADDHPVVRAGLRAVLETEPGLVILAEAATAEDAVARAAEGDIDVVLMDLQFGKGMGGAEATAQITARPG
APRVLIVTTYDSDADTLPAIEAGATGYLLKDAPPEDLAAAVRTAAAGRTTLAPTVADRLMNRLRTPGTSLTRRETEVLAL
VADGLSNQAIGVRLHLTEGTVKSHLARIYAKLDVDSRTAAVATATDLGLIRR

Nucleotide


Download         Length: 639 bp        

>NTDB_id=316849 E5N77_RS35785 WP_086878669.1 8006849..8007487(-) (vraR) [Streptomyces sp. SS52]
GTGACCGACGACACCCCGATCCGCTTGCTCCTGGCCGACGACCACCCCGTCGTACGGGCCGGACTGCGTGCCGTACTGGA
AACCGAACCGGGCCTCGTCATCCTGGCCGAAGCCGCCACCGCCGAGGACGCCGTCGCCCGCGCCGCCGAGGGCGACATCG
ACGTCGTCCTGATGGACCTGCAGTTCGGCAAGGGCATGGGCGGCGCCGAGGCCACCGCGCAGATCACCGCCCGCCCGGGA
GCCCCTCGCGTGCTGATCGTCACCACCTACGACTCCGACGCCGACACGCTACCCGCCATCGAAGCCGGCGCCACCGGCTA
CCTCCTCAAAGACGCCCCGCCCGAAGACCTGGCCGCAGCCGTGCGCACCGCGGCCGCCGGCCGGACCACCCTCGCACCCA
CCGTCGCCGACCGGCTGATGAACCGGCTGCGCACCCCGGGCACCTCCCTGACCCGGCGGGAAACCGAAGTCCTCGCCCTG
GTCGCCGACGGACTGTCCAACCAGGCCATCGGCGTACGCCTCCACCTGACCGAAGGCACCGTCAAGTCCCACCTGGCCCG
CATCTACGCCAAGCTCGACGTCGACTCCCGCACCGCCGCCGTCGCCACCGCAACCGACCTCGGCCTCATCCGTCGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(10-121)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.5

98.113

0.368

Multiple sequence alignment