Detailed information NTG0316549

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: D5H27_RS14690
• Genome accession: NZ_CP032506
• Coordinates: 2962154..2963317 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain JT3-1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 2957154..2968317

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D5H27_RS14660 (D5H27_14480)	-	2957418..2957837 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
D5H27_RS14665 (D5H27_14485)	comFC	2957911..2958600 (-)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
D5H27_RS14670 (D5H27_14490)	-	2958606..2958890 (-)	285	WP_003151389.1	competence protein ComFB	-
D5H27_RS14675 (D5H27_14495)	comFA	2958948..2960333 (-)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
D5H27_RS14680 (D5H27_14500)	-	2960442..2961290 (-)	849	WP_032876160.1	DegV family protein	-
D5H27_RS14685 (D5H27_14505)	degU	2961388..2962077 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
D5H27_RS14690 (D5H27_14510)	degS	2962154..2963317 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
D5H27_RS14695 (D5H27_14515)	-	2963540..2964187 (+)	648	WP_007614107.1	YigZ family protein	-
D5H27_RS14700 (D5H27_14520)	-	2964192..2965373 (+)	1182	WP_032876157.1	LCP family protein	-
D5H27_RS14705 (D5H27_14525)	-	2965472..2966548 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
D5H27_RS14710 (D5H27_14530)	-	2966681..2967877 (-)	1197	WP_032876154.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=316549 D5H27_RS14690 WP_007407484.1 2962154..2963317(-) (degS) [Bacillus velezensis strain JT3-1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=316549 D5H27_RS14690 WP_007407484.1 2962154..2963317(-) (degS) [Bacillus velezensis strain JT3-1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951