Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   D4L53_RS03400 Genome accession   NZ_CP032472
Coordinates   685403..687187 (-) Length   594 a.a.
NCBI ID   WP_139518378.1    Uniprot ID   -
Organism   Helicobacter pylori strain 479-A2-EK4     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 680403..692187
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4L53_RS03370 - 680947..681195 (+) 249 WP_000790557.1 RNA-binding protein -
  D4L53_RS03375 - 681397..682218 (-) 822 WP_139518376.1 glycosyltransferase family 25 protein -
  D4L53_RS03380 trxB 682434..683369 (-) 936 WP_097687835.1 thioredoxin-disulfide reductase -
  D4L53_RS03385 trxA 683374..683694 (-) 321 WP_000020204.1 thioredoxin -
  D4L53_RS03390 - 683783..684127 (-) 345 WP_127971174.1 YraN family protein -
  D4L53_RS03395 - 684127..685392 (-) 1266 WP_139518377.1 homoserine dehydrogenase -
  D4L53_RS03400 uvrC 685403..687187 (-) 1785 WP_139518378.1 excinuclease ABC subunit UvrC Machinery gene
  D4L53_RS03405 - 687188..687649 (-) 462 WP_139518379.1 hypothetical protein -
  D4L53_RS03410 - 687641..687820 (+) 180 WP_000468794.1 hypothetical protein -
  D4L53_RS03415 - 687832..688473 (-) 642 WP_139518380.1 ATP-binding cassette domain-containing protein -
  D4L53_RS03420 - 688475..690136 (-) 1662 WP_139518381.1 ABC transporter permease/substrate-binding protein -
  D4L53_RS03425 - 690205..690642 (-) 438 WP_001885597.1 hypothetical protein -
  D4L53_RS03430 motB 690648..691421 (-) 774 WP_139518382.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68655.90 Da        Isoelectric Point: 9.6226

>NTDB_id=316148 D4L53_RS03400 WP_139518378.1 685403..687187(-) (uvrC) [Helicobacter pylori strain 479-A2-EK4]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYSGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNEALKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEARSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENNAFQKDSYRRYHLKGSDEYAQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=316148 D4L53_RS03400 WP_139518378.1 685403..687187(-) (uvrC) [Helicobacter pylori strain 479-A2-EK4]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGCAAAGCCCCATGCGAGGATAAAATCACTAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAGCTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAGCAATTTGCGTTTTGAAGAAGCCCTAATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATAGTGGGAACAATAAGGCGGT
GTTGGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCAGAACAGATTTTATTAAAC
GCTTGCTCTAATGAAGCGCTTAAAGAATTGCAAGAATTTATCTCCCATCAATACTCTAAAAAAATCGCTCTTAATATTCC
TAAAAAGGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGCGCGATCGCTCTTCAAATTAGAATGCATGCCTTATAGGGTAGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCATTTCAAAAAGATTCTTATCGGCG
CTACCATTTGAAAGGCTCTGATGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGATTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATCGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCTAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTGAAAAAACGAATCTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.643

100

0.976

Multiple sequence alignment