Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   D4L66_RS03380 Genome accession   NZ_CP032471
Coordinates   686801..688585 (-) Length   594 a.a.
NCBI ID   WP_139535485.1    Uniprot ID   -
Organism   Helicobacter pylori strain 479-C2-EK2     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 681801..693585
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D4L66_RS03350 - 682345..682593 (+) 249 WP_000790557.1 RNA-binding protein -
  D4L66_RS03355 - 682795..683616 (-) 822 WP_139535483.1 glycosyltransferase family 25 protein -
  D4L66_RS03360 trxB 683832..684767 (-) 936 WP_097687835.1 thioredoxin-disulfide reductase -
  D4L66_RS03365 trxA 684772..685092 (-) 321 WP_000020204.1 thioredoxin -
  D4L66_RS03370 - 685181..685525 (-) 345 WP_127971174.1 YraN family protein -
  D4L66_RS03375 - 685525..686790 (-) 1266 WP_139535484.1 homoserine dehydrogenase -
  D4L66_RS03380 uvrC 686801..688585 (-) 1785 WP_139535485.1 excinuclease ABC subunit UvrC Machinery gene
  D4L66_RS03385 - 688586..689047 (-) 462 WP_139518379.1 hypothetical protein -
  D4L66_RS03390 - 689039..689218 (+) 180 WP_000468794.1 hypothetical protein -
  D4L66_RS03395 - 689230..689871 (-) 642 WP_139518380.1 ATP-binding cassette domain-containing protein -
  D4L66_RS03400 - 689873..691534 (-) 1662 WP_139518381.1 ABC transporter permease/substrate-binding protein -
  D4L66_RS03405 - 691603..692040 (-) 438 WP_001885597.1 hypothetical protein -
  D4L66_RS03410 motB 692046..692819 (-) 774 WP_139518382.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68623.88 Da        Isoelectric Point: 9.6704

>NTDB_id=316130 D4L66_RS03380 WP_139535485.1 686801..688585(-) (uvrC) [Helicobacter pylori strain 479-C2-EK2]
MADLLSSLKNLSNSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNHRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSINGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFNLECVPYRVEIFDT
SHHANNQCVGGMVVYENNAFQKNSYRRYHLKGSNEYAQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=316130 D4L66_RS03380 WP_139535485.1 686801..688585(-) (uvrC) [Helicobacter pylori strain 479-C2-EK2]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTAATAGCAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTATATCGGTAAAGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATCATCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCCTATATTTATATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCGTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGCAAAGCCCCATGCGAGGATAAAATCACTAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAGCTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAGCAATTTGCGTTTTGAAGAAGCCCTAATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTACGATTTGGATATTTTCGCTTTTTATGGTGCAAGCAATAAGGCAGT
GTTGGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCATTAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGACAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAGGTGCGATCGCTTTTCAACTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATGCCAACAACCAATGCGTGGGGGGAATGGTCGTGTATGAAAATAACGCTTTCCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGCTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCTAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGAGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAGGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTACTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.306

100

0.973

Multiple sequence alignment