Detailed information NTG0315889

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLB26_RS10550
• Genome accession: NZ_CP032435
• Coordinates: 2121934..2122965 (-)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain B26
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2116934..2127965

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLB26_RS10520 (LLB26_2067)	-	2118137..2118634 (-)	498	WP_011677211.1	nitroreductase family protein	-
LLB26_RS10525 (LLB26_2068)	-	2118621..2118830 (-)	210	WP_011677212.1	hypothetical protein	-
LLB26_RS10530 (LLB26_2069)	-	2118827..2119051 (-)	225	WP_021211256.1	hypothetical protein	-
LLB26_RS10535 (LLB26_2070)	-	2119118..2120008 (+)	891	WP_015082946.1	IS982 family transposase	-
LLB26_RS10540 (LLB26_2071)	kwcM	2120115..2121434 (-)	1320	WP_015082947.1	KxxxW cyclic peptide radical SAM maturase	-
LLB26_RS10545	-	2121502..2121615 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLB26_RS10550 (LLB26_2072)	sepM	2121934..2122965 (-)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
LLB26_RS10555 (LLB26_2073)	coaD	2122949..2123449 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
LLB26_RS10560 (LLB26_2074)	rsmD	2123497..2124036 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLB26_RS10565 (LLB26_2075)	-	2124206..2125426 (-)	1221	WP_011677216.1	MFS transporter	-
LLB26_RS10570 (LLB26_2076)	lmrP	2125506..2126732 (-)	1227	Protein_2093	multidrug efflux MFS transporter LmrP	-
LLB26_RS10575 (LLB26_2078)	-	2126920..2127414 (+)	495	WP_015082948.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=315889 LLB26_RS10550 WP_011677213.1 2121934..2122965(-) (sepM) [Lactococcus cremoris strain B26]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=315889 LLB26_RS10550 WP_011677213.1 2121934..2122965(-) (sepM) [Lactococcus cremoris strain B26]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49