Detailed information NTG0315842

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLW34_RS12065
• Genome accession: NZ_CP032430
• Coordinates: 2317204..2318235 (-)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain W34
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2312204..2323235

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLW34_RS12040 (LLW34_2348)	-	2313470..2313820 (-)	351	WP_242515032.1	nitroreductase family protein	-
LLW34_RS12045 (LLW34_2349)	-	2313887..2314777 (+)	891	WP_205288151.1	IS982-like element IS982B family transposase	-
LLW34_RS12050 (LLW34_2351)	-	2314991..2316102 (+)	1112	WP_205288157.1	IS3-like element IS981 family transposase	-
LLW34_RS12055 (LLW34_2352)	-	2316135..2316704 (-)	570	WP_242515033.1	radical SAM protein	-
LLW34_RS12060 (LLW34_03500)	-	2316772..2316885 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLW34_RS12065 (LLW34_2353)	sepM	2317204..2318235 (-)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
LLW34_RS12070 (LLW34_2354)	coaD	2318219..2318719 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
LLW34_RS12075 (LLW34_2355)	rsmD	2318767..2319306 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLW34_RS12080 (LLW34_2356)	-	2319477..2320697 (-)	1221	WP_011677216.1	MFS transporter	-
LLW34_RS12085 (LLW34_2357)	lmrP	2320781..2322007 (-)	1227	Protein_2350	multidrug efflux MFS transporter LmrP	-
LLW34_RS12090 (LLW34_2359)	-	2322195..2322689 (+)	495	WP_021211251.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=315842 LLW34_RS12065 WP_011677213.1 2317204..2318235(-) (sepM) [Lactococcus cremoris strain W34]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=315842 LLW34_RS12065 WP_011677213.1 2317204..2318235(-) (sepM) [Lactococcus cremoris strain W34]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49