Detailed information
Bioinformatically predicted
Overview
| Name | mecA | Type | Regulator |
| Locus tag | LLW34_RS03275 | Genome accession | NZ_CP032430 |
| Coordinates | 629649..630350 (+) | Length | 233 a.a. |
| NCBI ID | WP_011676802.1 | Uniprot ID | A0A0M2ZUZ8 |
| Organism | Lactococcus cremoris strain W34 | ||
| Function | degradation of ComX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 628100..667624 | 629649..630350 | within | 0 |
Gene organization within MGE regions
Location: 628100..667624
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LLW34_RS03265 (LLW34_0624) | - | 628100..628786 (+) | 687 | WP_014572148.1 | amino acid ABC transporter permease | - |
| LLW34_RS03270 (LLW34_0625) | - | 628786..629520 (+) | 735 | WP_011676803.1 | amino acid ABC transporter ATP-binding protein | - |
| LLW34_RS03275 (LLW34_0626) | mecA | 629649..630350 (+) | 702 | WP_011676802.1 | adaptor protein MecA | Regulator |
| LLW34_RS03280 (LLW34_0627) | - | 630353..631678 (+) | 1326 | WP_011676801.1 | MraY family glycosyltransferase | - |
| LLW34_RS03285 (LLW34_02790) | - | 631752..633136 (+) | 1385 | WP_205288033.1 | IS3 family transposase | - |
| LLW34_RS03290 (LLW34_0631) | - | 633210..634357 (+) | 1148 | WP_095559415.1 | IS3 family transposase | - |
| LLW34_RS03295 (LLW34_0632) | sufC | 634603..635373 (+) | 771 | WP_011676800.1 | Fe-S cluster assembly ATPase SufC | - |
| LLW34_RS03300 (LLW34_0633) | sufD | 635513..636769 (+) | 1257 | WP_021211874.1 | Fe-S cluster assembly protein SufD | - |
| LLW34_RS03305 (LLW34_0634) | - | 636769..637986 (+) | 1218 | WP_021211873.1 | cysteine desulfurase | - |
| LLW34_RS03310 (LLW34_0635) | - | 637988..638470 (+) | 483 | WP_031286519.1 | hypothetical protein | - |
| LLW34_RS03315 (LLW34_0636) | sufU | 638604..639062 (+) | 459 | WP_011676796.1 | Fe-S cluster assembly sulfur transfer protein SufU | - |
| LLW34_RS03320 (LLW34_0637) | sufB | 639158..640570 (+) | 1413 | WP_004255207.1 | Fe-S cluster assembly protein SufB | - |
| LLW34_RS03325 (LLW34_0638) | - | 640918..641208 (+) | 291 | WP_011676794.1 | WXG100 family type VII secretion target | - |
| LLW34_RS03330 (LLW34_0639) | - | 641316..641750 (+) | 435 | WP_021211585.1 | hypothetical protein | - |
| LLW34_RS03340 (LLW34_0642) | tenA | 643079..643735 (+) | 657 | WP_205288341.1 | thiaminase II | - |
| LLW34_RS03345 (LLW34_0643) | - | 644123..645301 (+) | 1179 | WP_205288342.1 | SLC13 family permease | - |
| LLW34_RS03350 (LLW34_0644) | - | 645474..646034 (+) | 561 | WP_011676776.1 | GNAT family N-acetyltransferase | - |
| LLW34_RS03355 (LLW34_0646) | - | 646134..647281 (+) | 1148 | WP_095559415.1 | IS3 family transposase | - |
| LLW34_RS03365 (LLW34_0649) | - | 648899..649297 (+) | 399 | WP_011676775.1 | hypothetical protein | - |
| LLW34_RS03370 (LLW34_0650) | - | 649403..650335 (+) | 933 | WP_014572202.1 | ABC transporter ATP-binding protein | - |
| LLW34_RS03375 (LLW34_0651) | - | 650332..651693 (+) | 1362 | WP_014572203.1 | ABC transporter permease | - |
| LLW34_RS03380 (LLW34_0652) | comEA | 651959..652405 (+) | 447 | WP_228763864.1 | helix-hairpin-helix domain-containing protein | Machinery gene |
| LLW34_RS03385 (LLW34_0653) | comEC | 652533..653759 (+) | 1227 | WP_332375356.1 | ComEC/Rec2 family competence protein | Machinery gene |
| LLW34_RS03390 (LLW34_0654) | comEC | 653800..654309 (+) | 510 | WP_021165649.1 | MBL fold metallo-hydrolase | Machinery gene |
| LLW34_RS03395 (LLW34_0655) | - | 654386..655276 (+) | 891 | WP_205288343.1 | IS982-like element ISLll1 family transposase | - |
| LLW34_RS03400 (LLW34_0656) | - | 655297..655602 (+) | 306 | Protein_654 | ComEC/Rec2 family competence protein | - |
| LLW34_RS03405 (LLW34_0657) | - | 655886..656662 (+) | 777 | WP_014572211.1 | alpha/beta hydrolase family protein | - |
| LLW34_RS03410 (LLW34_0658) | - | 656845..657060 (+) | 216 | WP_014572212.1 | F0F1 ATP synthase subunit C | - |
| LLW34_RS03415 (LLW34_0659) | atpB | 657107..657820 (+) | 714 | WP_004255255.1 | F0F1 ATP synthase subunit A | - |
| LLW34_RS03420 (LLW34_0660) | atpF | 657835..658341 (+) | 507 | WP_010906128.1 | F0F1 ATP synthase subunit B | - |
| LLW34_RS03425 (LLW34_0661) | - | 658343..658870 (+) | 528 | WP_014572213.1 | F0F1 ATP synthase subunit delta | - |
| LLW34_RS03430 (LLW34_0662) | atpA | 659058..660560 (+) | 1503 | WP_014572214.1 | F0F1 ATP synthase subunit alpha | - |
| LLW34_RS03435 (LLW34_0663) | - | 660576..661445 (+) | 870 | WP_011676766.1 | F0F1 ATP synthase subunit gamma | - |
| LLW34_RS03440 (LLW34_0664) | atpD | 661617..663026 (+) | 1410 | WP_021211822.1 | F0F1 ATP synthase subunit beta | - |
| LLW34_RS03445 (LLW34_0665) | - | 663211..663636 (+) | 426 | WP_011676764.1 | F0F1 ATP synthase subunit epsilon | - |
| LLW34_RS03450 (LLW34_0666) | - | 663740..664399 (+) | 660 | WP_259751054.1 | hypothetical protein | - |
| LLW34_RS03455 (LLW34_0667) | - | 664400..664696 (+) | 297 | WP_242515062.1 | hypothetical protein | - |
| LLW34_RS03460 (LLW34_0669) | - | 664752..665863 (+) | 1112 | WP_088792927.1 | IS3-like element IS981 family transposase | - |
| LLW34_RS03465 (LLW34_02800) | - | 665956..666168 (+) | 213 | WP_228764053.1 | hypothetical protein | - |
| LLW34_RS03470 (LLW34_02805) | - | 666276..666824 (+) | 549 | WP_014572218.1 | hypothetical protein | - |
| LLW34_RS03475 (LLW34_0671) | - | 666881..667624 (-) | 744 | WP_011676756.1 | amino acid ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 233 a.a. Molecular weight: 27046.46 Da Isoelectric Point: 4.1802
>NTDB_id=315804 LLW34_RS03275 WP_011676802.1 629649..630350(+) (mecA) [Lactococcus cremoris strain W34]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGAKKEEAEHEPDFIYYSIRYDDMMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKAKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLITTRALDVLRKI
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGAKKEEAEHEPDFIYYSIRYDDMMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKAKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLITTRALDVLRKI
Nucleotide
Download Length: 702 bp
>NTDB_id=315804 LLW34_RS03275 WP_011676802.1 629649..630350(+) (mecA) [Lactococcus cremoris strain W34]
ATGAAGTATGAGGATATAAATGAAAACACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAGTT
ATCTGACTTTTTTGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTAGTTGATGAACTTGGCTTAGAAAATCGTT
TTGGAAATGTAGGGATGTTAACTTTCCAAATTCAACCCTTCCCACAAGGCGTCCATATGATTGTTCATGAAGAAGCAATG
TTGGGTGAAGGCGGAGAGATTCCAGATGATCCTGAAGAATTTGAAGAATTAATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGACTTGGTTTACCAGGGGCTAAAAAAGAAG
AAGCCGAACATGAGCCAGACTTTATATACTACTCTATTCGTTATGATGACATGATGTCTGTCTTGACTGGAATAAAAAAT
GTGAAATTCGCAGATGAAGAGTCAGAATTTTATCGTTATGATGGTAATTTTTATCTTGTTGTTTTAGATAATCAAAAAGC
AAAAGGTAAAATGCATGTTGAAAGCACACGTTCACGGATGATGGAATATGGTGAAGCGACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGCCTAATCACAACGCGTGCTTTAGACGTTCTTAGAAAAATCTAA
ATGAAGTATGAGGATATAAATGAAAACACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAGTT
ATCTGACTTTTTTGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTAGTTGATGAACTTGGCTTAGAAAATCGTT
TTGGAAATGTAGGGATGTTAACTTTCCAAATTCAACCCTTCCCACAAGGCGTCCATATGATTGTTCATGAAGAAGCAATG
TTGGGTGAAGGCGGAGAGATTCCAGATGATCCTGAAGAATTTGAAGAATTAATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGACTTGGTTTACCAGGGGCTAAAAAAGAAG
AAGCCGAACATGAGCCAGACTTTATATACTACTCTATTCGTTATGATGACATGATGTCTGTCTTGACTGGAATAAAAAAT
GTGAAATTCGCAGATGAAGAGTCAGAATTTTATCGTTATGATGGTAATTTTTATCTTGTTGTTTTAGATAATCAAAAAGC
AAAAGGTAAAATGCATGTTGAAAGCACACGTTCACGGATGATGGAATATGGTGAAGCGACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGCCTAATCACAACGCGTGCTTTAGACGTTCTTAGAAAAATCTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| mecA | Lactococcus lactis subsp. cremoris KW2 |
100 |
100 |
1 |
| mecA | Lactococcus lactis subsp. lactis strain DGCC12653 |
96.567 |
100 |
0.966 |