Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   TFGB2_RS00370 Genome accession   NZ_CP032429
Coordinates   53005..56154 (-) Length   1049 a.a.
NCBI ID   WP_064662110.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain TFG-B2     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 38543..58117 53005..56154 within 0


Gene organization within MGE regions


Location: 38543..58117
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TFGB2_RS00300 (TFGB2_00037) orn 38922..39485 (-) 564 WP_003687260.1 oligoribonuclease -
  TFGB2_RS00305 (TFGB2_00038) prmA 39503..40390 (-) 888 WP_003687261.1 50S ribosomal protein L11 methyltransferase -
  TFGB2_RS00310 (TFGB2_00039) accC 40494..41855 (-) 1362 WP_003687264.1 acetyl-CoA carboxylase biotin carboxylase subunit -
  TFGB2_RS00315 (TFGB2_00040) accB 41967..42428 (-) 462 WP_003687267.1 acetyl-CoA carboxylase biotin carboxyl carrier protein -
  TFGB2_RS00320 - 42410..42667 (-) 258 WP_047917896.1 hypothetical protein -
  TFGB2_RS00325 (TFGB2_00041) queA 42784..43824 (+) 1041 WP_003687270.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
  TFGB2_RS00330 (TFGB2_00042) carB 44025..47240 (-) 3216 WP_003697927.1 carbamoyl-phosphate synthase large subunit -
  TFGB2_RS00335 (TFGB2_00043) - 47247..47795 (-) 549 WP_003687274.1 hypothetical protein -
  TFGB2_RS00340 (TFGB2_00044) - 47798..48361 (-) 564 WP_002214615.1 ComF family protein -
  TFGB2_RS00350 (TFGB2_00045) - 49541..49930 (-) 390 WP_003687278.1 endonuclease domain-containing protein -
  TFGB2_RS00355 (TFGB2_00046) - 50093..50472 (-) 380 Protein_49 VOC family protein -
  TFGB2_RS00360 (TFGB2_00047) carA 50526..51659 (-) 1134 WP_003700860.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  TFGB2_RS00370 (TFGB2_00048) pilC 53005..56154 (-) 3150 WP_064662110.1 PilC family type IV pilus tip adhesin Machinery gene

Sequence

Protein


Download         Length: 1049 a.a.        Molecular weight: 115295.49 Da        Isoelectric Point: 9.9093

>NTDB_id=315753 TFGB2_RS00370 WP_064662110.1 53005..56154(-) (pilC) [Neisseria gonorrhoeae strain TFG-B2]
MNKTLKRRVFRHTALYAAILMFSHTGGGGGAMAQTSNYAIIMNERKQPEVKWEGQYNQSALKDKSRERTFSHTSQRNSLG
RTSNFISFNNNDTLVSQQSGTAVFGTATYLPPYGKVSGFDTAELNKRGNAVNWIRTTRAGLAGYAYTGIRCGHARDCPKL
TYKTQFSFDNPDLAKTGDRLDRHTEPSRDNSPIYKLKDYPWLGVSFNLGAEGTAKDGRSSSRLISSFNEKNSNNNLVYTT
EGRDISLGNWQSESTAVAYYLNAKLHLLDKKEIKDITGKTVRLGVLKPSIDVKTQNTGFAGLLNFWSKWDIKDNGQIPVK
LGLPEVKAGRCTNKPNPNPKSKAPSPALTAPALWFGPVQNGKVQMYSASVSTYPGSSSSRIFLQELKTQTDPGRPGRYSL
AALNAQDIKSREPNFNSRQTVIRLPGGVYRIAPTRDRIVGLNGNDGKNDTFGIYKERLVTPDADEWAKVLLPWTVRYYGN
DDIFKTFNQPNSKTQNGKKQYSQKYRIRTKEDDNDKPRDLGDIVNSPITAVGGYLATSANDGMVHLFKRNGTDQRGYELK
LSYIPGTMERKDIEGNDSDLAKELRTFAEKGYVGDRYGVDGGFVLRRITDDQDKQKHFFMFGAMGLGGRGAYALDLSKID
SSNLTGVSMFDVQNDKNNNKNDSNRVKLGYTVGTPQIGKTQNGKYAAFLASGYAAKQIASQENTTALYVYDLENTLGTPI
AKIDVPGGKGGLSSPTLVDKDLDGTVDIAYAGDRGGNMYRFDLSDSNPSKWSVSTIFEGQRPITSAPAVSRLADKRVVIF
GTGSDLSESDVFNTDEQYIYGIFDDDKANVSVKVKDHMGDGLLKQNLTQENKTLFLTNNKASGGSADKGWVVKLREGERV
TVKPTVVLRTAFVTIRSYTGNDKCGAQTAILGINTADGGALTPRSARPIVPDHNSVAQYSGHKKTSKGKSIPIGCMEKGG
KTVCPNGYVYDKPVNVRYLDEKKTDDFPVTADGDAGGSGTFKEGKKPARNNRCFSGKGVRTLLMNDLDSLDITGPMCGIK
RLSWREVFF

Nucleotide


Download         Length: 3150 bp        

>NTDB_id=315753 TFGB2_RS00370 WP_064662110.1 53005..56154(-) (pilC) [Neisseria gonorrhoeae strain TFG-B2]
ATGAATAAAACTTTAAAAAGGCGGGTTTTCCGCCATACCGCGCTTTATGCCGCCATCTTGATGTTTTCCCATACCGGCGG
GGGGGGGGGGGCGATGGCGCAAACCAGTAACTACGCTATTATCATGAACGAGCGAAAGCAGCCCGAGGTAAAGTGGGAGG
GTCAATATAATCAATCAGCATTAAAGGACAAAAGCAGGGAGCGGACATTTAGCCATACGAGCCAGAGAAACAGCCTCGGC
AGGACAAGCAATTTTATCTCATTCAACAATAACGATACCCTTGTTTCTCAACAAAGCGGTACTGCCGTTTTTGGCACAGC
CACCTACCTGCCGCCCTACGGCAAGGTTTCCGGCTTTGATACCGCCGAGCTGAACAAGCGCGGCAATGCCGTCAATTGGA
TTCGTACCACCCGGGCCGGGCTGGCAGGCTACGCCTACACCGGTATCCGTTGCGGACATGCCCGAGACTGTCCCAAACTT
ACCTATAAAACCCAATTTTCCTTCGATAATCCCGACTTGGCAAAAACAGGAGACAGGCTGGATAGGCACACAGAGCCAAG
CCGCGACAATTCGCCCATTTACAAATTGAAGGATTATCCATGGTTGGGCGTGTCTTTCAATTTGGGCGCCGAGGGTACCG
CCAAAGATGGCAGATCATCCAGCAGATTGATATCTTCTTTTAATGAAAAGAATAGTAATAACAACCTCGTCTATACCACG
GAAGGCCGCGATATTTCCTTGGGCAACTGGCAGAGCGAAAGTACCGCCGTGGCCTATTATCTGAACGCCAAGCTGCACCT
GCTGGACAAAAAAGAGATTAAAGATATCACCGGCAAAACAGTGCGGTTGGGTGTCTTGAAGCCGAGCATCGATGTGAAGA
CACAAAATACGGGGTTTGCCGGCTTGCTAAATTTTTGGTCTAAGTGGGACATTAAAGATAACGGGCAGATTCCGGTCAAG
CTCGGCCTGCCGGAAGTCAAAGCCGGGCGCTGCACCAACAAACCGAACCCCAATCCCAAATCCAAAGCCCCTTCGCCGGC
ACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGCAAGGTGCAGATGTATTCCGCTTCGGTTTCTACCTACC
CCGGCAGTTCGAGCAGCCGCATCTTCCTCCAAGAGCTGAAAACTCAAACCGACCCCGGCAGGCCCGGCCGGTATTCCCTC
GCCGCTTTGAATGCGCAGGATATCAAATCCCGCGAGCCGAATTTCAACTCAAGGCAGACCGTCATCCGATTGCCGGGCGG
CGTGTACCGGATCGCCCCGACTCGCGACAGGATCGTGGGTTTGAATGGCAATGACGGCAAAAACGACACTTTCGGCATCT
ACAAGGAAAGGTTAGTCACACCTGATGCCGACGAGTGGGCAAAAGTGCTGCTGCCTTGGACGGTCCGGTATTACGGTAAT
GACGATATATTTAAAACATTCAACCAACCAAACAGCAAAACACAAAACGGCAAAAAACAATACAGCCAAAAATACCGCAT
CCGCACAAAAGAAGATGACAATGACAAACCCCGCGATTTGGGCGACATCGTCAACAGCCCGATAACGGCGGTCGGCGGGT
ATCTGGCAACTTCTGCCAACGACGGGATGGTGCACCTGTTTAAAAGAAACGGCACAGACCAACGAGGCTACGAACTGAAG
CTCAGCTACATCCCCGGTACGATGGAGCGTAAGGATATTGAAGGCAATGACTCCGACCTCGCCAAAGAGCTGCGCACCTT
TGCCGAAAAAGGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTCTTGCGCCGCATTACAGATGACCAAGACA
AGCAAAAACATTTCTTTATGTTTGGTGCGATGGGCCTTGGCGGCAGAGGCGCGTATGCCTTGGATTTAAGCAAAATCGAC
AGCAGCAACCTGACCGGCGTTTCCATGTTTGATGTCCAAAACGACAAAAATAACAATAAGAATGACAGTAATCGCGTGAA
ATTAGGCTACACCGTCGGTACGCCGCAAATCGGCAAAACCCAAAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATG
CGGCTAAACAAATTGCCAGCCAAGAAAATACAACCGCGCTGTATGTGTATGATTTGGAAAACACCTTAGGTACGCCGATT
GCAAAAATCGATGTGCCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCACAGTCGA
TATCGCCTATGCCGGCGACCGGGGCGGGAATATGTACCGCTTTGATTTGAGCGATTCCAATCCTAGTAAATGGTCTGTAA
GCACTATTTTCGAAGGCCAGAGGCCGATTACCTCCGCGCCCGCCGTTTCCCGACTGGCAGACAAACGCGTCGTTATCTTC
GGTACGGGCAGCGATTTGAGTGAAAGTGACGTATTCAATACGGACGAACAATATATTTACGGTATCTTTGACGACGATAA
GGCGAATGTTAGTGTAAAGGTAAAAGACCACATGGGCGACGGGCTGCTCAAGCAAAACCTTACGCAGGAAAATAAAACCT
TGTTCCTGACAAATAATAAGGCATCCGGCGGATCGGCCGATAAAGGCTGGGTAGTGAAATTGAGGGAAGGAGAACGCGTT
ACCGTCAAACCGACCGTGGTATTGCGTACCGCCTTTGTCACCATCCGCAGCTATACGGGTAATGACAAATGCGGCGCGCA
AACCGCCATTTTGGGCATCAATACCGCCGACGGCGGCGCATTGACTCCGAGAAGCGCGCGCCCGATTGTGCCGGATCACA
ATTCGGTTGCGCAATATTCCGGCCATAAGAAAACCTCCAAAGGCAAATCCATCCCTATAGGTTGTATGGAAAAAGGCGGT
AAAACCGTCTGCCCGAACGGATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGACGATTT
CCCCGTCACGGCAGACGGTGATGCAGGCGGCAGCGGAACATTCAAAGAGGGTAAAAAACCCGCCCGCAATAACCGGTGCT
TCTCCGGAAAAGGTGTGCGCACCCTGCTGATGAACGATTTGGACAGCTTGGATATTACCGGCCCGATGTGCGGTATCAAA
CGCTTAAGCTGGCGCGAAGTCTTCTTCTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(520-860)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

69.253

100

0.698

Multiple sequence alignment