Detailed information NTG0315499

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: D5R92_RS05025
• Genome accession: NZ_CP032401
• Coordinates: 1049537..1051984 (-)
• Length: 815 a.a.
• NCBI ID: WP_003100371.1
• Uniprot ID: -
• Organism: Streptococcus iniae strain GX005
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1044537..1056984

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D5R92_RS10235	-	1046945..1047274 (-)	330	WP_003100365.1	YSIRK-type signal peptide-containing protein	-
D5R92_RS05015 (D5R92_05015)	groL	1047445..1049073 (-)	1629	WP_003100367.1	chaperonin GroEL	-
D5R92_RS05020 (D5R92_05020)	groES	1049105..1049395 (-)	291	WP_003100369.1	co-chaperone GroES	-
D5R92_RS05025 (D5R92_05025)	clpC	1049537..1051984 (-)	2448	WP_003100371.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
D5R92_RS05030 (D5R92_05030)	-	1051987..1052445 (-)	459	WP_003100373.1	CtsR family transcriptional regulator	-
D5R92_RS05035 (D5R92_05035)	-	1052616..1052819 (-)	204	WP_016356203.1	cold-shock protein	-
D5R92_RS05040 (D5R92_05040)	-	1053103..1053369 (+)	267	WP_003100378.1	hypothetical protein	-
D5R92_RS05045 (D5R92_05045)	-	1053373..1055436 (+)	2064	WP_003100380.1	sodium:proton antiporter	-
D5R92_RS05055 (D5R92_05055)	ahpC	1055941..1056504 (+)	564	WP_003100382.1	alkyl hydroperoxide reductase subunit C	-

Sequence

Protein

• Length: 815 a.a.
• Molecular weight: 90326.91 Da
• Isoelectric Point: 6.6034

>NTDB_id=315499 D5R92_RS05025 WP_003100371.1 1049537..1051984(-) (clpC) [Streptococcus iniae strain GX005]
MINYSNKMQEIFKHAQFQAARFESHYLETWHILLAMVAVENSLAGLVFSEFESKIAVEEYEAAAILAMGKSPKESVRGFE
LKLQSKSLEHILNFANAISQVTNEKEVGSEHVLFAILLNPDIMASRVLELAGYKMKDDGSGEPRLVDLRKAIEIHAAYSK
ETIKAIYELRKPKKAKAGGSFSEMMKPPSTAGDLSDFTRDLTELAHQGLLEPVIGREKEISRMVQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIATGAIPYELQEMRVLELDMMSVVAGTRFRGDFEERMNQIIADIEEDGHIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKVLIEEPNLEDAYAIISGLKSSYEQFHNVLISD
EAARASVKLAHRYLTSKQLPDSAIDLLDEASATVQGMVKKDPPSPLNAIDKAIIEGDFKAVSKLLKQDKPSPKLKPTPVT
EAHILKTLSQLSGIPVEKLSQADSKKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGMLTDSRGRRVDFSNTIIIMTSNLGATALRDDKTVGFGAKAISHDHTAMEKRILEELKKAYKPEFINRIDEKVVFH
SLSQEDMRQVVMIMVQPLINTLAEKRISLKLQPSALKYLSEKGYDVEMGARPLRRTLQTEIEDKLSELILSGQLSAGHAL
KIGMSQGKLKYDISS

Nucleotide

• Length: 2448 bp

>NTDB_id=315499 D5R92_RS05025 WP_003100371.1 1049537..1051984(-) (clpC) [Streptococcus iniae strain GX005]
ATGATCAATTATTCCAATAAAATGCAGGAGATTTTTAAACATGCTCAATTTCAAGCAGCACGTTTTGAAAGTCATTATTT
AGAAACTTGGCATATATTATTAGCTATGGTAGCTGTTGAAAATTCTTTGGCAGGCCTTGTTTTCAGTGAGTTTGAATCAA
AAATTGCTGTTGAAGAATATGAAGCGGCAGCTATTTTAGCAATGGGCAAAAGCCCTAAGGAATCTGTCAGAGGATTTGAA
CTAAAATTACAGTCAAAGAGTTTGGAACACATCCTAAACTTTGCTAATGCTATTAGTCAGGTAACCAATGAAAAAGAAGT
TGGTTCTGAGCATGTTTTGTTTGCAATTTTATTAAATCCTGACATTATGGCTAGTCGCGTCTTGGAACTAGCAGGTTATA
AAATGAAAGATGATGGCAGCGGTGAGCCACGTTTAGTGGATCTTCGTAAGGCTATTGAAATTCATGCAGCTTATAGTAAA
GAGACCATTAAAGCCATTTATGAATTGCGTAAACCTAAAAAAGCTAAGGCAGGTGGAAGCTTCTCAGAGATGATGAAGCC
GCCTAGCACTGCGGGAGACTTATCAGATTTTACGCGCGATTTAACAGAACTTGCTCATCAAGGCTTGCTTGAGCCAGTTA
TTGGACGTGAAAAAGAGATTTCTCGCATGGTCCAAGTACTTAGCCGTAAAACTAAGAATAATCCTGTTCTTGTTGGAGAT
GCTGGGGTTGGTAAAACAGCTCTTGCCTATGGGCTAGCACAACGCATTGCAACAGGTGCTATTCCGTATGAGTTGCAAGA
AATGCGTGTTTTGGAACTTGATATGATGAGCGTGGTGGCTGGGACGCGTTTTAGAGGTGACTTTGAAGAACGTATGAATC
AAATCATTGCTGATATTGAAGAGGATGGCCATATCATTTTGTTTGTGGATGAACTACACACAATAATGGGTTCAGGAAGT
GGCATTGACAGTACATTAGATGCAGCCAATATCTTAAAACCAGCCCTATCACGTGGGACGCTTCATATGGTTGGCGCAAC
AACCCAAGAAGAATATCAAAAACACATTGAAAAAGATGCAGCTCTCTCAAGACGTTTTGCTAAAGTTTTAATTGAAGAAC
CCAATTTAGAAGATGCTTATGCTATTATTTCAGGGCTTAAATCATCTTATGAGCAATTTCATAATGTGCTTATTTCTGAC
GAGGCGGCTCGCGCTAGTGTTAAGTTAGCCCATCGCTATTTAACCAGCAAGCAGCTTCCAGATTCGGCTATTGATTTATT
AGATGAAGCTAGTGCTACTGTTCAAGGAATGGTAAAAAAAGACCCCCCATCACCTTTAAATGCTATTGATAAGGCAATCA
TAGAAGGTGATTTTAAGGCAGTTTCGAAATTGCTTAAGCAAGATAAGCCTAGTCCTAAATTAAAGCCAACTCCTGTTACA
GAGGCTCATATTCTAAAAACCTTAAGTCAATTATCAGGTATTCCAGTTGAAAAATTAAGTCAAGCAGACAGTAAAAAATA
TTTGAATTTGGAAAAAGAGTTGCATAAGCGTGTTATTGGTCAAGAAGATGCAGTATCAGCTATTTCAAGGGCTATTCGTC
GTAATCAATCAGGAATTAGAACAGGCAAGCGCCCAATTGGTTCCTTCATGTTCCTTGGGCCAACAGGTGTTGGTAAGACA
GAACTTGCCAAAGCCTTAGCTGAAGTCTTATTTGATGATGAGTCTGCCTTAATTCGTTTTGACATGTCTGAATACATGGA
AAAATTTGCGGCAAGCCGTTTAAATGGTGCTCCTCCAGGCTATGTTGGCTATGATGAAGGTGGAGAATTGACCGAAAAAG
TGCGCAACAAACCTTATTCGGTTTTACTCTTTGATGAAGTTGAAAAAGCCCATCCAGATATCTTTAATGTTTTGTTGCAA
GTTTTAGATGATGGGATGTTGACAGATAGTCGTGGTCGTCGTGTTGATTTCTCAAATACCATTATTATCATGACAAGTAA
CCTTGGTGCAACAGCCTTGCGTGATGACAAGACGGTTGGTTTTGGAGCCAAAGCCATTAGCCATGACCATACTGCCATGG
AAAAACGCATTTTAGAAGAACTTAAAAAAGCCTATAAACCAGAATTTATCAATAGAATTGATGAAAAAGTGGTCTTCCAT
AGCTTGAGTCAAGAAGACATGCGTCAAGTGGTTATGATTATGGTGCAGCCATTGATAAATACCTTAGCAGAAAAAAGGAT
CTCCCTCAAACTTCAACCATCGGCCCTTAAGTACCTTTCAGAAAAAGGATATGATGTGGAAATGGGTGCTCGTCCTCTTA
GACGTACCCTCCAGACAGAAATTGAAGATAAATTGTCAGAGCTCATTTTATCAGGTCAGCTCTCAGCTGGTCATGCCTTG
AAAATTGGTATGTCGCAAGGGAAATTAAAATACGATATCTCTTCATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-800)

• AAA lid domain (AAA_lid_9) (376-453)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-51)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (106-132)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	75.4	99.755	0.752
clpC	Streptococcus thermophilus LMG 18311	70.588	100	0.707
clpC	Streptococcus thermophilus LMD-9	70.588	100	0.707
clpC	Streptococcus pneumoniae Rx1	65.686	100	0.658
clpC	Streptococcus pneumoniae D39	65.686	100	0.658
clpC	Streptococcus pneumoniae TIGR4	65.564	100	0.656
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.321	100	0.494
clpC	Bacillus subtilis subsp. subtilis str. 168	42.548	100	0.434