Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   D5R92_RS01215 Genome accession   NZ_CP032401
Coordinates   250836..251699 (-) Length   287 a.a.
NCBI ID   WP_003099993.1    Uniprot ID   A0A3L8GIC3
Organism   Streptococcus iniae strain GX005     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 245836..256699
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D5R92_RS01195 (D5R92_01195) - 246090..246470 (-) 381 WP_003099988.1 OsmC family protein -
  D5R92_RS01200 (D5R92_01200) pheT 246543..248948 (-) 2406 WP_003099989.1 phenylalanine--tRNA ligase subunit beta -
  D5R92_RS01205 (D5R92_01205) - 248964..249488 (-) 525 WP_003099991.1 N-acetyltransferase -
  D5R92_RS01210 (D5R92_01210) pheS 249501..250544 (-) 1044 WP_003099992.1 phenylalanine--tRNA ligase subunit alpha -
  D5R92_RS01215 (D5R92_01215) endA 250836..251699 (-) 864 WP_003099993.1 DNA/RNA non-specific endonuclease Machinery gene
  D5R92_RS01220 (D5R92_01220) - 251730..251918 (-) 189 WP_003099995.1 DNA-directed RNA polymerase subunit beta -
  D5R92_RS01225 (D5R92_01225) murA 251922..253193 (-) 1272 WP_003099997.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  D5R92_RS01230 (D5R92_01230) - 253259..253495 (-) 237 WP_071794729.1 DUF1146 family protein -
  D5R92_RS01235 (D5R92_01235) - 253571..253987 (-) 417 WP_003100001.1 F0F1 ATP synthase subunit epsilon -
  D5R92_RS01240 (D5R92_01240) atpD 254000..255406 (-) 1407 WP_003100002.1 F0F1 ATP synthase subunit beta -
  D5R92_RS01245 (D5R92_01245) - 255522..256397 (-) 876 WP_003100004.1 F0F1 ATP synthase subunit gamma -

Sequence

Protein


Download         Length: 287 a.a.        Molecular weight: 31715.35 Da        Isoelectric Point: 9.3865

>NTDB_id=315474 D5R92_RS01215 WP_003099993.1 250836..251699(-) (endA) [Streptococcus iniae strain GX005]
MSPKTKQSQKINLLLFLLVLVGLFYLIDSKEGEENNPIRAFYQSVMGASNQTSQKESSNPDTPSYALASSVLTEKVKRQL
GSKVEWNGNGAFVINDNSTNLDAKVSSAPYAHNQTRLLSGKKLPTVANALLAKSTRQYRDRNETGNGYSYWKPAGWHQIH
GLSGKYDHAVDRGHLLGYALVGGLKGFDASTSNSDNIATQLSWANQAMDSDSTGQNYYETKIRRALDKNKRVRYRVTLIY
EADNILASGSHLEAKSDDGSLEFNVFVPNVQKGLEVDYQTGQITVSH

Nucleotide


Download         Length: 864 bp        

>NTDB_id=315474 D5R92_RS01215 WP_003099993.1 250836..251699(-) (endA) [Streptococcus iniae strain GX005]
ATGTCACCAAAGACAAAACAAAGTCAAAAAATCAATCTATTATTGTTTCTGCTTGTGCTCGTTGGCTTATTCTATTTGAT
TGATAGTAAAGAAGGGGAAGAGAATAATCCTATTCGAGCCTTTTATCAATCAGTGATGGGAGCTTCCAATCAAACTAGCC
AAAAAGAATCAAGCAATCCTGATACACCAAGTTATGCCTTGGCATCTTCGGTTTTAACAGAAAAAGTAAAAAGACAACTT
GGTTCGAAAGTTGAGTGGAATGGTAATGGTGCATTTGTCATCAATGATAACAGTACCAATTTGGATGCAAAAGTATCCAG
TGCTCCCTATGCTCACAATCAAACCAGACTCTTATCAGGGAAAAAGCTTCCAACAGTCGCCAATGCTTTACTTGCCAAAT
CAACAAGGCAATACCGAGACCGAAACGAGACCGGAAATGGCTACTCTTATTGGAAACCTGCTGGTTGGCACCAGATTCAT
GGTTTATCAGGAAAATATGATCACGCTGTGGACCGTGGGCATTTATTAGGCTATGCTTTAGTGGGAGGTCTTAAAGGATT
TGATGCCTCTACAAGCAATAGCGATAACATAGCAACGCAATTATCCTGGGCTAACCAAGCGATGGATAGTGATTCCACTG
GCCAAAATTATTATGAAACAAAAATCAGACGTGCATTGGACAAGAATAAGCGTGTCCGTTACCGTGTTACCCTCATTTAC
GAGGCTGATAATATATTAGCAAGTGGAAGCCATTTAGAAGCAAAATCAGATGACGGCAGTTTAGAATTTAACGTTTTTGT
GCCAAATGTTCAAAAAGGTCTAGAAGTTGACTATCAAACAGGACAAATAACAGTCAGTCACTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(95-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L8GIC3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

63.559

82.23

0.523
  endA Streptococcus pneumoniae D39

63.559

82.23

0.523
  endA Streptococcus pneumoniae R6

63.559

82.23

0.523
  endA Streptococcus pneumoniae TIGR4

63.559

82.23

0.523

Multiple sequence alignment