Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   TFGA2_RS02625 Genome accession   NZ_CP032398
Coordinates   449104..449769 (+) Length   221 a.a.
NCBI ID   WP_047918678.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain TFG-A2     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 444104..454769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TFGA2_RS02590 (TFGA2_00449) cysT 444225..445061 (-) 837 WP_003687907.1 sulfate ABC transporter permease subunit CysT -
  TFGA2_RS02595 (TFGA2_00450) - 445242..445574 (+) 333 WP_003687908.1 hypothetical protein -
  TFGA2_RS02600 (TFGA2_00451) - 445905..446414 (+) 510 WP_003687909.1 isoprenylcysteine carboxyl methyltransferase family protein -
  TFGA2_RS02610 (TFGA2_00452) - 446646..447227 (-) 582 WP_047918049.1 superoxide dismutase -
  TFGA2_RS02620 (TFGA2_00453) dnaB 447390..448796 (+) 1407 WP_134797838.1 replicative DNA helicase -
  TFGA2_RS02625 (TFGA2_00454) pilH 449104..449769 (+) 666 WP_047918678.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  TFGA2_RS02630 (TFGA2_00455) pilV 449801..450409 (+) 609 WP_003692820.1 type IV pilus modification protein PilV Machinery gene
  TFGA2_RS02635 (TFGA2_00456) pilJ 450406..451350 (+) 945 WP_047916984.1 PilW family protein Machinery gene
  TFGA2_RS02640 (TFGA2_00457) pilK 451329..451940 (+) 612 WP_003687918.1 PilX N-terminal domain-containing pilus assembly protein Machinery gene
  TFGA2_RS02645 (TFGA2_00458) pilL 451942..452415 (+) 474 WP_025455870.1 PilX family type IV pilin Machinery gene
  TFGA2_RS02650 (TFGA2_00459) - 452485..452793 (-) 309 WP_010951048.1 AzlD family protein -
  TFGA2_RS02655 - 452790..453497 (-) 708 Protein_457 AzlC family ABC transporter permease -
  TFGA2_RS02660 (TFGA2_00461) dut 453663..454115 (+) 453 WP_047918679.1 dUTP diphosphatase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 24613.96 Da        Isoelectric Point: 8.6140

>NTDB_id=315380 TFGA2_RS02625 WP_047918678.1 449104..449769(+) (pilH) [Neisseria gonorrhoeae strain TFG-A2]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQIANLLRFSRGEAVRLNLPVYICPAQVKKDGTVD
NQCDFGKKEQGMLAFGDKNDNKAYDGDAADVFLRNVVLNDDIKDKRINYTFNHIAFGSSQPTADRVVWTFNQNGTFGYTK
DQHLASTSSFFYSDGYIQIVLTDARAVSDADRKFRSAVVLIDSSGRVEVCRKNDTRAVCKH

Nucleotide


Download         Length: 666 bp        

>NTDB_id=315380 TFGA2_RS02625 WP_047918678.1 449104..449769(+) (pilH) [Neisseria gonorrhoeae strain TFG-A2]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGCCCAAGTTAAAAAAGACGGTACGGTCGAC
AACCAATGCGACTTCGGTAAGAAGGAACAGGGGATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCTGCGGATGTTTTTCTCCGTAACGTGGTATTGAATGATGATATCAAGGATAAGCGGATTAATTACACCTTCAATCATA
TCGCTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTGCAAGCACATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAGGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACG
ATACGCGCGCCGTATGCAAACATTAA

Domains

Predicted by InterProScan.

Type II transport protein GspH (GspH)

(44-205)

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

86.878

100

0.869

Multiple sequence alignment