Detailed information
Bioinformatically predicted
Overview
| Name | pilH | Type | Machinery gene |
| Locus tag | TFGA2_RS02625 | Genome accession | NZ_CP032398 |
| Coordinates | 449104..449769 (+) | Length | 221 a.a. |
| NCBI ID | WP_047918678.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain TFG-A2 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 442103..490502 | 449104..449769 | within | 0 |
Gene organization within MGE regions
Location: 442103..490502
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| TFGA2_RS02580 (TFGA2_00447) | - | 442103..443179 (-) | 1077 | WP_003687905.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| TFGA2_RS02585 (TFGA2_00448) | cysW | 443176..444036 (-) | 861 | WP_003687906.1 | sulfate ABC transporter permease subunit CysW | - |
| TFGA2_RS02590 (TFGA2_00449) | cysT | 444225..445061 (-) | 837 | WP_003687907.1 | sulfate ABC transporter permease subunit CysT | - |
| TFGA2_RS02595 (TFGA2_00450) | - | 445242..445574 (+) | 333 | WP_003687908.1 | hypothetical protein | - |
| TFGA2_RS02600 (TFGA2_00451) | - | 445905..446414 (+) | 510 | WP_003687909.1 | isoprenylcysteine carboxyl methyltransferase family protein | - |
| TFGA2_RS02610 (TFGA2_00452) | - | 446646..447227 (-) | 582 | WP_047918049.1 | superoxide dismutase | - |
| TFGA2_RS02620 (TFGA2_00453) | dnaB | 447390..448796 (+) | 1407 | WP_134797838.1 | replicative DNA helicase | - |
| TFGA2_RS02625 (TFGA2_00454) | pilH | 449104..449769 (+) | 666 | WP_047918678.1 | Tfp pilus assembly protein FimT/FimU | Machinery gene |
| TFGA2_RS02630 (TFGA2_00455) | pilV | 449801..450409 (+) | 609 | WP_003692820.1 | type IV pilus modification protein PilV | Machinery gene |
| TFGA2_RS02635 (TFGA2_00456) | pilJ | 450406..451350 (+) | 945 | WP_047916984.1 | PilW family protein | Machinery gene |
| TFGA2_RS02640 (TFGA2_00457) | pilK | 451329..451940 (+) | 612 | WP_003687918.1 | PilX N-terminal domain-containing pilus assembly protein | Machinery gene |
| TFGA2_RS02645 (TFGA2_00458) | pilL | 451942..452415 (+) | 474 | WP_025455870.1 | PilX family type IV pilin | Machinery gene |
| TFGA2_RS02650 (TFGA2_00459) | - | 452485..452793 (-) | 309 | WP_010951048.1 | AzlD family protein | - |
| TFGA2_RS02655 | - | 452790..453497 (-) | 708 | Protein_457 | AzlC family ABC transporter permease | - |
| TFGA2_RS02660 (TFGA2_00461) | dut | 453663..454115 (+) | 453 | WP_047918679.1 | dUTP diphosphatase | - |
| TFGA2_RS02665 (TFGA2_00462) | dapC | 454191..455378 (+) | 1188 | WP_047918680.1 | succinyldiaminopimelate transaminase | - |
| TFGA2_RS02670 (TFGA2_00463) | yaaA | 455689..456468 (+) | 780 | WP_047918681.1 | peroxide stress protein YaaA | - |
| TFGA2_RS02685 | - | 456998..458190 (+) | 1193 | Protein_461 | tyrosine-type recombinase/integrase | - |
| TFGA2_RS02695 (TFGA2_00467) | - | 458546..458815 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| TFGA2_RS02700 (TFGA2_00469) | - | 459010..459693 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| TFGA2_RS13680 | - | 459973..460239 (-) | 267 | Protein_464 | hypothetical protein | - |
| TFGA2_RS02710 (TFGA2_00471) | - | 460350..460565 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| TFGA2_RS02715 (TFGA2_00472) | - | 460617..461108 (-) | 492 | WP_003691537.1 | siphovirus Gp157 family protein | - |
| TFGA2_RS02720 (TFGA2_00473) | - | 461105..461287 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| TFGA2_RS02725 (TFGA2_00474) | - | 461603..462112 (-) | 510 | WP_262393700.1 | phage replication initiation protein, NGO0469 family | - |
| TFGA2_RS02730 (TFGA2_00475) | - | 462181..462342 (-) | 162 | WP_003691530.1 | hypothetical protein | - |
| TFGA2_RS02735 (TFGA2_00476) | - | 462339..462614 (-) | 276 | WP_003703838.1 | NGO1622 family putative holin | - |
| TFGA2_RS02740 (TFGA2_00477) | - | 462767..463099 (-) | 333 | WP_003695500.1 | hypothetical protein | - |
| TFGA2_RS02745 (TFGA2_00478) | - | 463240..463479 (-) | 240 | WP_134797839.1 | hypothetical protein | - |
| TFGA2_RS02750 (TFGA2_00479) | - | 463476..463952 (-) | 477 | WP_002255718.1 | DUF6948 domain-containing protein | - |
| TFGA2_RS02755 (TFGA2_00480) | - | 463985..464185 (-) | 201 | WP_047919800.1 | hypothetical protein | - |
| TFGA2_RS02760 (TFGA2_00481) | - | 464668..464982 (+) | 315 | WP_262393701.1 | hypothetical protein | - |
| TFGA2_RS13685 (TFGA2_00482) | - | 464941..465774 (-) | 834 | WP_262393702.1 | hypothetical protein | - |
| TFGA2_RS02775 (TFGA2_00483) | - | 465931..466629 (-) | 699 | Protein_477 | helix-turn-helix transcriptional regulator | - |
| TFGA2_RS02790 | - | 467590..467757 (+) | 168 | WP_262393703.1 | helix-turn-helix domain-containing protein | - |
| TFGA2_RS14285 | - | 467754..468752 (+) | 999 | Protein_479 | helix-turn-helix domain-containing protein | - |
| TFGA2_RS13700 | - | 469030..469167 (-) | 138 | WP_262393717.1 | hypothetical protein | - |
| TFGA2_RS13705 (TFGA2_00487) | - | 469195..469538 (+) | 344 | Protein_481 | ATP-binding protein | - |
| TFGA2_RS02805 | - | 469531..469836 (+) | 306 | WP_262393705.1 | hypothetical protein | - |
| TFGA2_RS02810 (TFGA2_00488) | - | 469850..470344 (+) | 495 | WP_003691434.1 | DUF3310 domain-containing protein | - |
| TFGA2_RS02815 (TFGA2_00489) | - | 470521..470670 (+) | 150 | WP_003689110.1 | hypothetical protein | - |
| TFGA2_RS13710 | - | 470878..471147 (+) | 270 | WP_262393706.1 | hypothetical protein | - |
| TFGA2_RS02825 (TFGA2_00491) | - | 471108..471404 (+) | 297 | WP_262393707.1 | RusA family crossover junction endodeoxyribonuclease | - |
| TFGA2_RS02830 (TFGA2_00492) | - | 471397..471702 (+) | 306 | WP_003687981.1 | nuclease domain-containing protein | - |
| TFGA2_RS02835 (TFGA2_00493) | - | 471699..472082 (+) | 384 | WP_003687982.1 | recombination protein NinB | - |
| TFGA2_RS02840 (TFGA2_00494) | - | 472073..472591 (+) | 519 | WP_003687984.1 | HNH endonuclease | - |
| TFGA2_RS02845 (TFGA2_00495) | - | 472656..473078 (+) | 423 | WP_003704254.1 | hypothetical protein | - |
| TFGA2_RS02850 (TFGA2_00496) | - | 473078..473320 (+) | 243 | WP_003706439.1 | hypothetical protein | - |
| TFGA2_RS02855 (TFGA2_00497) | - | 473375..473617 (+) | 243 | WP_003687989.1 | hypothetical protein | - |
| TFGA2_RS02860 (TFGA2_00498) | - | 473598..474872 (+) | 1275 | WP_003687990.1 | PBSX family phage terminase large subunit | - |
| TFGA2_RS02865 (TFGA2_00499) | - | 474857..477124 (+) | 2268 | WP_003687991.1 | hypothetical protein | - |
| TFGA2_RS02870 (TFGA2_00500) | - | 477361..478557 (+) | 1197 | WP_003687992.1 | hypothetical protein | - |
| TFGA2_RS02875 (TFGA2_00501) | - | 478554..479924 (+) | 1371 | WP_187357182.1 | hypothetical protein | - |
| TFGA2_RS14290 (TFGA2_00502) | - | 479924..485854 (+) | 5931 | WP_082279199.1 | PLxRFG domain-containing protein | - |
| TFGA2_RS02890 (TFGA2_00504) | - | 486480..487772 (+) | 1293 | WP_003687995.1 | DUF4043 family protein | - |
| TFGA2_RS02895 (TFGA2_00505) | - | 487827..488300 (+) | 474 | WP_003687996.1 | hypothetical protein | - |
| TFGA2_RS02900 (TFGA2_00506) | - | 488306..488791 (+) | 486 | WP_003687997.1 | hypothetical protein | - |
| TFGA2_RS02905 (TFGA2_00507) | - | 488788..489462 (+) | 675 | WP_003687998.1 | hypothetical protein | - |
| TFGA2_RS02910 (TFGA2_00508) | - | 489453..489614 (+) | 162 | WP_003687999.1 | hypothetical protein | - |
| TFGA2_RS02915 (TFGA2_00509) | - | 489651..490502 (-) | 852 | WP_050162101.1 | Bro-N domain-containing protein | - |
Sequence
Protein
Download Length: 221 a.a. Molecular weight: 24613.96 Da Isoelectric Point: 8.6140
>NTDB_id=315380 TFGA2_RS02625 WP_047918678.1 449104..449769(+) (pilH) [Neisseria gonorrhoeae strain TFG-A2]
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQIANLLRFSRGEAVRLNLPVYICPAQVKKDGTVD
NQCDFGKKEQGMLAFGDKNDNKAYDGDAADVFLRNVVLNDDIKDKRINYTFNHIAFGSSQPTADRVVWTFNQNGTFGYTK
DQHLASTSSFFYSDGYIQIVLTDARAVSDADRKFRSAVVLIDSSGRVEVCRKNDTRAVCKH
MCTRKQQGFTLTELLIVMAIAAIMATIALPNMSGWIASRRIASHAEQIANLLRFSRGEAVRLNLPVYICPAQVKKDGTVD
NQCDFGKKEQGMLAFGDKNDNKAYDGDAADVFLRNVVLNDDIKDKRINYTFNHIAFGSSQPTADRVVWTFNQNGTFGYTK
DQHLASTSSFFYSDGYIQIVLTDARAVSDADRKFRSAVVLIDSSGRVEVCRKNDTRAVCKH
Nucleotide
Download Length: 666 bp
>NTDB_id=315380 TFGA2_RS02625 WP_047918678.1 449104..449769(+) (pilH) [Neisseria gonorrhoeae strain TFG-A2]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGCCCAAGTTAAAAAAGACGGTACGGTCGAC
AACCAATGCGACTTCGGTAAGAAGGAACAGGGGATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCTGCGGATGTTTTTCTCCGTAACGTGGTATTGAATGATGATATCAAGGATAAGCGGATTAATTACACCTTCAATCATA
TCGCTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTGCAAGCACATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAGGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACG
ATACGCGCGCCGTATGCAAACATTAA
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGCCATTGCAGCCATTATGGCGACGAT
AGCCCTCCCCAATATGAGTGGGTGGATTGCATCACGCCGCATTGCCAGTCACGCGGAGCAGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGCCCAAGTTAAAAAAGACGGTACGGTCGAC
AACCAATGCGACTTCGGTAAGAAGGAACAGGGGATGTTGGCTTTCGGCGACAAAAACGACAATAAGGCATATGACGGCGA
TGCTGCGGATGTTTTTCTCCGTAACGTGGTATTGAATGATGATATCAAGGATAAGCGGATTAATTACACCTTCAATCATA
TCGCTTTCGGTTCGTCTCAGCCGACCGCCGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATACGAAA
GACCAGCATCTTGCAAGCACATCCAGCTTTTTTTATTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAGGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTCGAAGTTTGTCGTAAAAACG
ATACGCGCGCCGTATGCAAACATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilH | Neisseria gonorrhoeae MS11 |
86.878 |
100 |
0.869 |