Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   TFGA2_RS01610 Genome accession   NZ_CP032398
Coordinates   279463..281670 (+) Length   735 a.a.
NCBI ID   WP_180376644.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain TFG-A2     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 274463..286670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TFGA2_RS01605 (TFGA2_00271) - 274479..279077 (-) 4599 WP_047918592.1 S6 family peptidase -
  TFGA2_RS13110 - 279156..279431 (-) 276 WP_153707850.1 hypothetical protein -
  TFGA2_RS01610 (TFGA2_00272) comA 279463..281670 (+) 2208 WP_180376644.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  TFGA2_RS01615 (TFGA2_00273) comL 281740..282543 (-) 804 WP_003687645.1 outer membrane protein assembly factor BamD Machinery gene
  TFGA2_RS01620 (TFGA2_00274) rluD 282542..283666 (+) 1125 WP_003687642.1 23S rRNA pseudouridine(1911/1915/1917) synthase RluD -
  TFGA2_RS01625 (TFGA2_00275) - 283819..284766 (-) 948 Protein_276 bile acid:sodium symporter family protein -
  TFGA2_RS01635 (TFGA2_00276) pgeF 285219..285998 (+) 780 WP_003687651.1 peptidoglycan editing factor PgeF -
  TFGA2_RS01640 (TFGA2_00277) lptE 286050..286529 (+) 480 WP_003687653.1 LPS assembly lipoprotein LptE -

Sequence

Protein


Download         Length: 735 a.a.        Molecular weight: 79424.12 Da        Isoelectric Point: 10.3677

>NTDB_id=315375 TFGA2_RS01610 WP_180376644.1 279463..281670(+) (comA) [Neisseria gonorrhoeae strain TFG-A2]
MFRRWFLPCWVVGVAVSFALSVVPHWPFWLAAFAVLAVLARRFAFAGLMLCVLAGAAYGVFRTEAALSSQWRAEAVSGVP
LTVEVTDMPRSDGRRVQFAAKAVDSGGRTFDLLLSDYKRREWAVGSRWRITARVHPVVGELNLRGLNREAWALSNGVGGV
GTVGADRVLLHGGSGWGIAVWRSRISRNWRQADADGGLSDGIGLMRALSVGEQSALRPGLWQAFRPLGLTHLVSISGLHV
TMVAVLFAWLAKRLLACSPRLPARPRAWVLAAGCAGALFYALLAGFSVPTQRSVLMLAAFAWAWRRGRLSAWATWWQALA
AVLLFDPLAVLGVGTWLSFGLVAALIWACAGRLYEGKRQTAVRGQWAASVLSLVLLGYLFASLPLVNAVSIPWFSWVLTP
LALLGSVVPFAPLQQAGAFLAEYTLRFLVWLADVSPEFAVAAAPLPLLVLAVCAALLLLLPRGLGLRPWAVLLLAGFVSY
RPEAVPENEAAVTVWDAGQGLSVLVRTANRHLLFDTGTVAAAQTGIVPSLNAAGVRRLDKLVLSHHDSDHDGGFQAVGKI
PNGGIYAGQPEFYEGARHCAEQRWQWDGVDFEFLRPSERKNIDDNGKSCVLRVVAGGAALLVTGDLDTKGEESLVGKYGG
NLYSQVLVLGHHGSNTSSSGVFLNAVSPEYAVASSGYANAYKHPTEAVQNRVRAHGIKLLRTDLSGALQFGLGRGGVKAQ
RLRVYKFYWQKKPFE

Nucleotide


Download         Length: 2208 bp        

>NTDB_id=315375 TFGA2_RS01610 WP_180376644.1 279463..281670(+) (comA) [Neisseria gonorrhoeae strain TFG-A2]
GTGTTCCGTCGTTGGTTTTTGCCGTGTTGGGTTGTCGGCGTGGCAGTTTCGTTCGCACTGTCGGTTGTACCGCATTGGCC
GTTTTGGTTGGCGGCTTTTGCGGTTTTGGCTGTGCTTGCAAGGCGTTTTGCGTTTGCCGGTCTGATGCTGTGCGTGTTGG
CGGGCGCGGCTTACGGCGTATTCAGAACGGAAGCGGCACTGTCTTCGCAATGGCGGGCGGAGGCGGTTTCAGGCGTGCCT
TTGACGGTGGAAGTGACGGATATGCCGAGGTCGGACGGGCGGCGCGTGCAGTTTGCGGCAAAGGCTGTGGACAGCGGCGG
TCGGACGTTTGATTTGCTGCTGTCGGACTACAAACGGCGCGAATGGGCGGTCGGGAGCAGATGGCGGATAACGGCACGCG
TGCACCCCGTCGTCGGGGAGTTGAACCTGCGCGGTTTGAACCGTGAGGCGTGGGCATTATCCAACGGGGTAGGCGGCGTG
GGGACGGTCGGTGCGGACAGGGTTTTGCTGCATGGCGGAAGCGGTTGGGGGATTGCGGTTTGGCGCAGCCGCATCAGCCG
CAATTGGCGGCAGGCGGATGCGGACGGCGGGCTTTCAGACGGCATCGGGCTGATGCGCGCGTTGAGCGTGGGCGAACAGT
CGGCATTGCGCCCCGGATTGTGGCAGGCGTTCCGGCCGTTGGGGCTGACGCATTTGGTCAGTATCTCGGGTTTGCACGTT
ACGATGGTGGCGGTGCTGTTTGCGTGGCTGGCGAAGCGGCTGCTTGCCTGTTCCCCGCGCCTTCCCGCCCGGCCGCGCGC
GTGGGTTTTGGCGGCGGGGTGTGCGGGCGCGCTGTTTTACGCGCTGCTTGCCGGTTTTTCCGTGCCGACGCAGCGCAGTG
TTTTGATGTTGGCGGCGTTCGCGTGGGCGTGGCGCAGGGGAAGACTGTCGGCGTGGGCGACGTGGTGGCAGGCGTTGGCG
GCGGTGCTGCTGTTCGACCCTTTGGCGGTTTTGGGTGTCGGTACTTGGCTGTCTTTCGGTTTGGTGGCGGCCCTGATATG
GGCGTGTGCAGGGCGTTTGTACGAGGGGAAACGGCAAACCGCCGTGCGCGGGCAGTGGGCGGCTTCGGTGTTGTCTCTGG
TTTTGCTCGGTTATCTGTTTGCCTCGCTGCCTTTGGTCAATGCGGTGTCGATACCGTGGTTTTCTTGGGTGTTGACCCCG
CTGGCGTTGCTGGGTTCGGTCGTGCCGTTTGCGCCGCTTCAGCAGGCGGGGGCATTTTTGGCGGAATACACTTTGCGGTT
TTTGGTGTGGCTTGCCGATGTGTCGCCTGAGTTTGCCGTTGCCGCCGCACCTTTGCCGCTGCTGGTGTTGGCGGTGTGTG
CCGCTTTGCTGTTGCTGCTGCCGCGCGGCTTGGGTTTGCGTCCGTGGGCGGTGTTGCTGTTGGCAGGGTTTGTATCCTAC
CGTCCTGAAGCAGTACCTGAAAACGAAGCTGCGGTTACGGTTTGGGATGCGGGGCAGGGCTTGTCGGTGCTTGTGCGGAC
GGCAAACCGCCATCTGCTTTTCGATACGGGAACGGTAGCGGCGGCACAAACGGGTATCGTGCCGAGTTTGAATGCGGCGG
GTGTCCGCCGTTTGGACAAGCTGGTTCTGTCGCATCACGACAGCGACCACGACGGCGGCTTTCAGGCAGTCGGCAAGATA
CCGAACGGCGGGATTTATGCCGGACAGCCGGAATTTTATGAGGGGGCGCGGCATTGTGCGGAACAGCGTTGGCAATGGGA
CGGCGTGGATTTCGAGTTTTTGAGGCCGTCTGAACGCAAAAATATCGATGATAATGGGAAAAGTTGTGTTTTGCGTGTTG
TGGCGGGCGGTGCGGCACTGCTGGTAACGGGCGATTTGGATACGAAGGGCGAGGAAAGCCTGGTCGGCAAGTATGGAGGC
AACCTGTACAGCCAGGTGTTGGTGTTGGGGCATCACGGCAGCAATACGTCCTCGTCGGGCGTGTTCCTCAATGCCGTTTC
GCCCGAATATGCCGTTGCTTCAAGCGGTTATGCCAACGCCTACAAGCATCCGACCGAAGCGGTGCAGAACCGTGTCCGCG
CACACGGCATCAAGTTGTTGCGGACGGATTTGTCGGGCGCGCTGCAATTCGGCTTGGGACGCGGAGGCGTAAAGGCTCAA
CGTTTGAGAGTGTATAAATTCTATTGGCAGAAAAAACCGTTTGAGTGA

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(496-673)

Domain of unknown function (DUF4131) (DUF4131)

(7-167)

Competence protein (Competence)

(208-461)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

99.459

100

1

Multiple sequence alignment