Detailed information NTG0031536

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: LFERR_RS11750
• Genome accession: NC_011206
• Coordinates: 2344263..2345294 (-)
• Length: 343 a.a.
• NCBI ID: WP_009568264.1
• Uniprot ID: A0A2W1KN79
• Organism: Acidithiobacillus ferrooxidans ATCC 53993
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2339263..2350294

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LFERR_RS11720 (Lferr_2367)	hslV	2339473..2340012 (+)	540	WP_009565976.1	ATP-dependent protease subunit HslV	-
LFERR_RS11725 (Lferr_2368)	hslU	2340015..2341337 (+)	1323	WP_012537366.1	ATP-dependent protease ATPase subunit HslU	-
LFERR_RS11730 (Lferr_2369)	-	2341360..2341692 (-)	333	WP_009568269.1	hypothetical protein	-
LFERR_RS11735 (Lferr_2370)	rpoH	2341689..2342549 (-)	861	WP_012537367.1	RNA polymerase sigma factor RpoH	-
LFERR_RS11740 (Lferr_2371)	ftsX	2342693..2343598 (-)	906	WP_009568267.1	permease-like cell division protein FtsX	-
LFERR_RS11745 (Lferr_2372)	ftsE	2343595..2344266 (-)	672	WP_009568266.1	cell division ATP-binding protein FtsE	-
LFERR_RS11750 (Lferr_2373)	pilA	2344263..2345294 (-)	1032	WP_009568264.1	signal recognition particle-docking protein FtsY	Machinery gene
LFERR_RS11755 (Lferr_2374)	rsmD	2345417..2345986 (+)	570	WP_009568262.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LFERR_RS11760 (Lferr_2375)	coaD	2345979..2346503 (+)	525	WP_012537368.1	pantetheine-phosphate adenylyltransferase	-
LFERR_RS11765 (Lferr_2376)	-	2346532..2346783 (+)	252	WP_012537369.1	YfhL family 4Fe-4S dicluster ferredoxin	-
LFERR_RS11770 (Lferr_2377)	-	2346767..2348746 (-)	1980	WP_012537370.1	dynamin family protein	-
LFERR_RS11775 (Lferr_2378)	mutM	2348763..2349575 (-)	813	WP_009567582.1	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 36809.09 Da
• Isoelectric Point: 6.8862

>NTDB_id=31536 LFERR_RS11750 WP_009568264.1 2344263..2345294(-) (pilA) [Acidithiobacillus ferrooxidans ATCC 53993]
MVFDWFKRNKSLPAGETFAEEVNSPATVATIPEDTPKGLFSRLRQGLARSREQLAGGVGRLVLGKKVIDADLLEELEALL
LQADLGSAATREVMDSVTERVRRNELTDPAALQAALRESLLDILRPRAQPWSPEKGHSQVLLMVGINGAGKTTTIGKLAA
RWKAEGFTVVLAAGDTFRAAAVEQLQGWGRRAQVPVVAQGTGADSASVIFDALTTTRARGSDLLIADTAGRLHTQGHLME
ELKKIRRVLGKQDPEAPQQIWLVLDAGTGQNALNQARQFHDAVGLTGICITKLDGTAKGGVVAAIAKALPIPIRYIGVGE
QVEDLRPFDPESFVDALFAESKS

Nucleotide

• Length: 1032 bp

>NTDB_id=31536 LFERR_RS11750 WP_009568264.1 2344263..2345294(-) (pilA) [Acidithiobacillus ferrooxidans ATCC 53993]
ATGGTGTTCGACTGGTTCAAGCGTAACAAAAGCCTCCCTGCGGGGGAAACGTTCGCCGAAGAGGTGAACTCCCCTGCCAC
TGTGGCGACTATCCCGGAAGATACCCCCAAGGGACTTTTCTCTCGTCTTCGGCAAGGTCTGGCCCGCAGCCGGGAACAAC
TGGCCGGGGGTGTAGGGCGTCTGGTACTTGGTAAAAAGGTTATCGATGCCGATCTGCTGGAAGAACTGGAAGCCTTGCTG
CTACAGGCGGATCTCGGCAGCGCCGCAACCCGCGAAGTCATGGACAGCGTCACGGAGCGGGTGCGTCGCAACGAACTCAC
GGACCCCGCCGCGCTCCAGGCGGCACTGCGCGAGTCGCTTCTGGATATCCTGCGTCCCCGCGCACAACCCTGGTCGCCCG
AGAAGGGGCATTCTCAGGTGTTGCTCATGGTCGGTATCAACGGCGCAGGCAAAACGACCACCATCGGTAAACTGGCGGCA
CGCTGGAAGGCGGAAGGTTTCACGGTGGTGCTTGCTGCCGGGGACACCTTCCGCGCCGCTGCCGTCGAGCAGTTGCAGGG
CTGGGGGAGGCGCGCGCAGGTGCCGGTGGTGGCTCAGGGTACGGGCGCTGACAGCGCCTCCGTGATTTTCGATGCGCTGA
CCACGACCCGCGCGCGTGGCAGCGACCTGCTCATCGCCGATACCGCCGGGCGCCTCCACACCCAAGGCCATCTCATGGAA
GAGTTGAAGAAGATCAGGCGGGTTCTCGGCAAACAGGATCCGGAGGCGCCGCAGCAGATCTGGTTGGTGCTGGACGCCGG
GACGGGGCAGAACGCCCTCAATCAGGCACGTCAGTTTCATGACGCCGTGGGGCTGACGGGTATTTGCATCACCAAGCTGG
ATGGCACCGCCAAGGGGGGCGTGGTGGCGGCCATCGCCAAGGCCCTGCCCATCCCCATTCGCTACATTGGTGTCGGTGAG
CAGGTCGAAGACTTGCGTCCCTTTGACCCCGAATCCTTTGTCGATGCCTTGTTTGCGGAGTCGAAGTCATGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (139-338)

• SRP54-type protein, helical bundle domain (SRP54_N) (63-120)

3D structure

• AlphaFold DB: A0A2W1KN79

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	52.778	94.461	0.499