Detailed information NTG0315205

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: D4A37_RS22275
• Genome accession: NZ_CP032365
• Coordinates: 4270145..4271188 (-)
• Length: 347 a.a.
• NCBI ID: WP_001013192.1
• Uniprot ID: A0AAU8F9J6
• Organism: Bacillus wiedmannii strain SR52
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 4265145..4276188

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D4A37_RS22240	-	4266048..4266392 (+)	345	WP_151035580.1	helix-turn-helix transcriptional regulator	-
D4A37_RS22245	-	4266593..4267762 (+)	1170	WP_151035581.1	site-specific integrase	-
D4A37_RS30335	-	4267905..4268093 (-)	189	Protein_4319	hypothetical protein	-
D4A37_RS22255	-	4268063..4268365 (-)	303	WP_000829516.1	hypothetical protein	-
D4A37_RS22260	comGD	4268358..4268813 (-)	456	WP_000810391.1	comG operon protein ComGD	-
D4A37_RS22265	comGC	4268810..4269109 (-)	300	WP_001178692.1	competence type IV pilus major pilin ComGC	-
D4A37_RS22270	comGB	4269121..4270152 (-)	1032	WP_000473556.1	competence type IV pilus assembly protein ComGB	-
D4A37_RS22275	comGA	4270145..4271188 (-)	1044	WP_001013192.1	competence protein ComGA	Machinery gene
D4A37_RS22280	-	4271394..4272089 (+)	696	WP_000434122.1	helix-turn-helix domain-containing protein	-
D4A37_RS22285	-	4272216..4272458 (+)	243	WP_000440719.1	DUF2626 domain-containing protein	-
D4A37_RS22290	-	4272564..4273958 (+)	1395	WP_001094324.1	L-cystine transporter	-
D4A37_RS22295	-	4274358..4274573 (-)	216	WP_001008334.1	DUF3912 family protein	-
D4A37_RS22300	-	4274827..4275138 (+)	312	WP_001093232.1	hypothetical protein	-
D4A37_RS22305	-	4275177..4275665 (-)	489	WP_000764276.1	hypothetical protein	-
D4A37_RS22310	-	4275745..4276119 (-)	375	WP_001012499.1	nucleoside 2-deoxyribosyltransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39354.93 Da
• Isoelectric Point: 9.0695

>NTDB_id=315205 D4A37_RS22275 WP_001013192.1 4270145..4271188(-) (comGA) [Bacillus wiedmannii strain SR52]
MNGIESFANMILKEACRVQASDLHIVPRKKDVVVQLRIGKDLMTKHCIEKEFGEKLVSHFKFLASMDIGERRKPQNGSLY
LQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHLSLFPSTAKKLLSFLHYSHGLLVFTGPTGSGKTTTMYALLEV
IRKKKTRRIVTLEDPVEKRNDDVLQIQINEKAGITYEAGLKAILRHDPDIILVGEIRDEETAKIAIRASLTGHLVMTTLH
TNDAKGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTLCKSMRQVRQASIYELLYGYELKQAIKEANGEC
VTYKHETLESSIRKGYALGFLEEDVYV

Nucleotide

• Length: 1044 bp

>NTDB_id=315205 D4A37_RS22275 WP_001013192.1 4270145..4271188(-) (comGA) [Bacillus wiedmannii strain SR52]
ATGAATGGAATTGAAAGCTTTGCGAATATGATTTTGAAAGAGGCGTGTAGGGTACAAGCTTCGGATTTACATATTGTGCC
CAGGAAGAAGGATGTAGTGGTTCAACTGCGTATAGGAAAAGATTTAATGACGAAACACTGTATCGAGAAGGAATTTGGAG
AAAAACTTGTTTCACACTTTAAATTTTTAGCATCCATGGATATAGGGGAGAGACGGAAGCCACAAAATGGTTCACTGTAT
TTACAAATGGATGGACAAGAAGTGTATTTACGCCTTTCCACGCTTCCAACCGTATACCAAGAAAGTCTCGTTATTCGTCT
TCATTTACAAGCATCTATCCAGCCGTTATCTCATCTTTCGTTATTTCCAAGTACAGCGAAAAAACTACTCTCTTTTTTAC
ATTATTCCCATGGATTACTCGTATTTACTGGACCGACTGGTTCTGGAAAGACAACAACAATGTATGCATTATTAGAGGTC
ATTAGAAAAAAGAAAACACGTCGCATCGTTACACTGGAAGATCCAGTTGAAAAAAGAAATGACGATGTATTACAAATTCA
AATAAATGAAAAAGCAGGTATCACATATGAGGCAGGATTAAAGGCTATTTTACGTCATGATCCAGATATTATTTTAGTCG
GTGAAATTCGTGATGAAGAAACAGCGAAAATCGCTATAAGAGCAAGTTTGACTGGCCATTTAGTAATGACGACACTGCAT
ACTAATGATGCGAAAGGGGCGATACTCCGATTTATGGATTTCGGTATAACGAGGCAAGAGATTGAACAATCTTTATTGGC
TATAGCTGCACAGCGACTTGTCGAATTGAAGTGTCCGTTTTGCAAAAGAAAGTGCTCAACTTTATGTAAATCAATGAGGC
AAGTAAGACAAGCGAGTATTTATGAGTTGTTATATGGATATGAGTTAAAACAAGCGATTAAAGAAGCAAACGGGGAATGT
GTCACGTACAAGCACGAAACATTAGAATCTTCGATACGAAAAGGATACGCTTTAGGATTTTTAGAAGAGGATGTGTATGT
TTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (10-275)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Bacillus subtilis subsp. subtilis str. 168	58.213	100	0.582
pilB	Vibrio campbellii strain DS40M4	35.411	100	0.36