Detailed information NTG0314240

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: D3P10_RS04690
• Genome accession: NZ_CP032159
• Coordinates: 949144..950187 (+)
• Length: 347 a.a.
• NCBI ID: WP_002466111.1
• Uniprot ID: A0A5F0TYQ0
• Organism: Staphylococcus warneri strain 22.1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 944144..955187

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D3P10_RS04665 (D3P10_04665)	-	945200..945925 (+)	726	WP_023373124.1	type 1 glutamine amidotransferase	-
D3P10_RS04670 (D3P10_04670)	-	945993..946979 (-)	987	WP_015364857.1	FUSC family protein	-
D3P10_RS04675 (D3P10_04675)	map	947146..947901 (+)	756	WP_002466104.1	type I methionyl aminopeptidase	-
D3P10_RS04680 (D3P10_04680)	-	948045..948431 (+)	387	WP_002466133.1	DUF2543 family protein	-
D3P10_RS04685 (D3P10_04685)	liaF	948446..949147 (+)	702	WP_015364858.1	cell wall-active antibiotics response protein LiaF	-
D3P10_RS04690 (D3P10_04690)	vraS	949144..950187 (+)	1044	WP_002466111.1	sensor histidine kinase	Regulator
D3P10_RS04695 (D3P10_04695)	vraR	950177..950806 (+)	630	WP_058710065.1	response regulator transcription factor	Regulator
D3P10_RS04700 (D3P10_04700)	-	950865..952100 (-)	1236	WP_015364859.1	YihY/virulence factor BrkB family protein	-
D3P10_RS04705 (D3P10_04705)	-	952346..952615 (-)	270	WP_119176356.1	YtxH domain-containing protein	-
D3P10_RS04710 (D3P10_04710)	-	952622..953086 (-)	465	WP_002466141.1	low molecular weight protein-tyrosine-phosphatase	-
D3P10_RS04715 (D3P10_04715)	-	953233..953436 (+)	204	WP_002466135.1	DUF1128 domain-containing protein	-
D3P10_RS04720 (D3P10_04720)	-	953449..954690 (+)	1242	WP_058710066.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40087.57 Da
• Isoelectric Point: 6.2449

>NTDB_id=314240 D3P10_RS04690 WP_002466111.1 949144..950187(+) (vraS) [Staphylococcus warneri strain 22.1]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=314240 D3P10_RS04690 WP_002466111.1 949144..950187(+) (vraS) [Staphylococcus warneri strain 22.1]
ATGAATCACTATATAAGAGCTATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCGTTCTTATTTATTGATAA
AGTTTTTGTCAACATCATTTACTTTCAAGGAATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTTTTAAATA
TTATAGTTATATTATTATGTATTATAGTTGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACTGTTGGAATTAATGATCAAAATATTGAATTGTATAGCGAGACGTTAGAAAT
ATATCATACACTTGTCCCGTTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAGATTATTGAAGATGAGCGACAACGCTTAGCTAGAGAATTACATGATTCTGTAAGC
CAACAATTATTCGCTGCGAGTATGATGTTATCTGCAATAAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
CGTACTTGAAAAGATGGTTCAAGATTCACAACTAGAGATGAGAGCATTGTTACTTCATTTAAGACCATTAGGATTAAAAG
ATAAATCATTAGGTGAAGGTATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTACCAATGAAAGTAGTGCATGAAATT
CAAGAATTTAAAGTGCCAAAAGGAATTGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACATTGAGACA
TTCTAATGGCACAAGAGTAACGGTTGAATTATTTAATAAGCAAGATTATCTGCTTTTACGTATACAAGATAATGGCAAAG
GTTTTAATGTAGATGAGAAACTTGAACAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACC
TTCCATATCGTATCGTTACCAGACTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A5F0TYQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.813	100	0.948