Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   D3C60_RS05755 Genome accession   NZ_CP032144
Coordinates   1104375..1105031 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain BIM B-439D     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1099375..1110031
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D3C60_RS05730 (D3C60_05730) oppF 1099904..1100821 (+) 918 WP_020955632.1 oligopeptide ABC transporter ATP-binding protein OppF -
  D3C60_RS05735 (D3C60_05735) - 1100928..1102115 (+) 1188 WP_042635052.1 putative glycoside hydrolase -
  D3C60_RS05740 (D3C60_05740) - 1102233..1102811 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  D3C60_RS05745 (D3C60_05745) spx 1102990..1103385 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  D3C60_RS05750 (D3C60_05750) - 1103443..1104099 (-) 657 WP_007409109.1 TerC family protein -
  D3C60_RS20050 - 1104282..1104392 (+) 111 Protein_1064 adaptor protein MecA -
  D3C60_RS05755 (D3C60_05755) mecA 1104375..1105031 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  D3C60_RS05760 (D3C60_05760) - 1105182..1106342 (+) 1161 WP_007409108.1 competence protein CoiA family protein -
  D3C60_RS05765 (D3C60_05765) pepF 1106570..1108399 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  D3C60_RS19885 - 1108437..1108604 (-) 168 WP_003155026.1 hypothetical protein -
  D3C60_RS05770 (D3C60_05770) spxH 1108890..1109792 (-) 903 WP_007409106.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=313911 D3C60_RS05755 WP_003155032.1 1104375..1105031(+) (mecA) [Bacillus velezensis strain BIM B-439D]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=313911 D3C60_RS05755 WP_003155032.1 1104375..1105031(+) (mecA) [Bacillus velezensis strain BIM B-439D]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment