Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E3155_RS10530 Genome accession   NZ_CP038394
Coordinates   2166255..2166911 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli O55:H7 strain DEC5A     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2161255..2171911
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3155_RS10500 (E3155_10775) dcyD 2162134..2163120 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  E3155_RS10505 (E3155_10780) tcyL 2163135..2163803 (+) 669 WP_001158226.1 cystine ABC transporter permease -
  E3155_RS10510 (E3155_10785) tcyN 2163800..2164552 (+) 753 WP_001273005.1 L-cystine ABC transporter ATP-binding protein TcyN -
  E3155_RS10515 (E3155_10790) sdiA 2164782..2165504 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  E3155_RS10520 (E3155_10795) yecF 2165572..2165796 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  E3155_RS10525 (E3155_10800) yecU 2165783..2165959 (-) 177 WP_001302050.1 protein YecU -
  E3155_RS26840 (E3155_10805) - 2165997..2166113 (-) 117 WP_001302039.1 hypothetical protein -
  E3155_RS10530 (E3155_10810) letA 2166255..2166911 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  E3155_RS10535 (E3155_10815) uvrC 2166908..2168740 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  E3155_RS10540 (E3155_10820) pgsA 2168797..2169345 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  E3155_RS10560 (E3155_10840) yecA 2169994..2170659 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=313860 E3155_RS10530 WP_000611328.1 2166255..2166911(+) (letA) [Escherichia coli O55:H7 strain DEC5A]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=313860 E3155_RS10530 WP_000611328.1 2166255..2166911(+) (letA) [Escherichia coli O55:H7 strain DEC5A]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTAAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCTGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CATTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACGAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment