Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   SEZ_RS00855 Genome accession   NC_011134
Coordinates   151371..153812 (+) Length   813 a.a.
NCBI ID   WP_037583944.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus MGCS10565     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 146371..158812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SEZ_RS00820 (Sez_0134) rpsB 146560..147330 (-) 771 WP_012677249.1 30S ribosomal protein S2 -
  SEZ_RS00830 (Sez_0135) ahpF 147791..149322 (-) 1532 Protein_132 alkyl hydroperoxide reductase subunit F -
  SEZ_RS00835 (Sez_0137) ahpC 149343..149903 (-) 561 WP_012514798.1 alkyl hydroperoxide reductase subunit C -
  SEZ_RS00845 (Sez_0138) - 150535..150738 (+) 204 WP_012514799.1 cold-shock protein -
  SEZ_RS00850 (Sez_0139) - 150910..151371 (+) 462 WP_012514800.1 CtsR family transcriptional regulator -
  SEZ_RS00855 (Sez_0140) clpC 151371..153812 (+) 2442 WP_037583944.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  SEZ_RS10110 - 154156..154301 (-) 146 Protein_137 putative holin-like toxin -
  SEZ_RS00865 (Sez_0141) - 154581..155012 (+) 432 WP_012514802.1 hypothetical protein -
  SEZ_RS00870 (Sez_0142) - 155014..156303 (+) 1290 WP_041785213.1 hypothetical protein -
  SEZ_RS00875 (Sez_0143) - 156285..156677 (+) 393 WP_041785214.1 hypothetical protein -
  SEZ_RS00880 (Sez_0144) - 156658..156948 (+) 291 WP_012514805.1 hypothetical protein -
  SEZ_RS00885 (Sez_0145) groES 157248..157535 (+) 288 WP_012514806.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 813 a.a.        Molecular weight: 90379.20 Da        Isoelectric Point: 6.4808

>NTDB_id=31356 SEZ_RS00855 WP_037583944.1 151371..153812(+) (clpC) [Streptococcus equi subsp. zooepidemicus MGCS10565]
MMTYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLAAMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQF
KPQSKALSEILAFAHAICQVTNEHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
TIKAIHELRKPKKTKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKEVSRMVQVLCRKTKNNPVLVGDA
GVGKTALAYGLAQRIASGVIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSG
IDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVDDAYQILLGLRASYEQYHNVTISDK
AVHTAVKLAQRYLTSKRLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQALLDGDMSKVSALLAKEDKQPKLKPTAVTE
DDMLHTLSKLSGIPLEKLTQADSKKYLNLEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFDEVEKAHPDIFNILLQV
LDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHS
LTQENMRDVVKIMVKPLIAALAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQSLK
IGVSHGKLAFDIA

Nucleotide


Download         Length: 2442 bp        

>NTDB_id=31356 SEZ_RS00855 WP_037583944.1 151371..153812(+) (clpC) [Streptococcus equi subsp. zooepidemicus MGCS10565]
GTGATGACTTATTCATTAAAGATGCAAGACATTTTTAATCAGGCTCAATTTCAGGCAGAGCGCTTTGATAGTCCTTACCT
TGAGACCTGGCACATTTTATTAGCTATGGTAGCTGTTGATCATTCTTTAGCAGCCATGGTTTTAAGCGAATTTGAACGAA
AGATCAGAGCTGAAGAGTATGAGGCAGCTGCTATTTTAGCTATGGGAAAAAGTCCCAAGGAGGTGACTTCTGTCCAATTC
AAGCCGCAATCCAAGGCCTTATCAGAAATACTAGCATTTGCTCATGCTATCTGTCAGGTCACCAATGAGCATGAGGTTGG
CTCAGAGCATGTGCTTTTTGCTATTTTGCTCAATCCGGACATTATGGCTAGTCGTCTATTAGAATTGGCAGGCTATAGGC
TTAAGGATTCTGGCAAGGGAGAGCCTAGGTTTGCGGATTTACGTAAGGCTATTGAGTTAAATGCCGGCTATAGTAAGGAA
ACCATTAAGGCGATTCATGAGTTGCGTAAGCCTAAAAAGACGAAATCAGTAGGCACCTTTTCTGAAATGATGAAGCCACA
GAGTACAGCTGGTGAGCTATCAGACTTTACTAGAGACCTGACAGAGATGGCAAGACAGGGCTTGTTAGAGCCAGTTATCG
GACGAGAAAAAGAGGTGTCACGTATGGTTCAGGTGCTCTGTCGTAAGACTAAAAATAATCCTGTTCTTGTTGGTGATGCG
GGTGTTGGAAAAACTGCTCTAGCTTATGGCTTGGCACAGCGTATTGCAAGCGGCGTGATTCCTTATGAATTACAGGACAT
GCGTGTCTTGGAGCTTGACATGATGAGTGTGGTTGCAGGTACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATCAAC
TCATTGACGATATTGAAGCAGATGGCAAAATCATCTTGTTTGTCGATGAGCTACATACCATTATGGGATCAGGAAGTGGT
ATTGACAGCACTCTTGATGCAGCTAATATTCTAAAGCCAGCCCTTTCTCGCGGTACCCTGCATATGGTTGGCGCTACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAGGACGCAGCTCTTTCTCGTCGCTTTGCCAAGATATTGATTGAGGAGCCTA
GTGTCGATGATGCTTATCAGATTTTGCTTGGCTTGAGGGCCTCCTATGAACAGTACCATAATGTAACAATCTCTGATAAA
GCTGTTCATACTGCTGTGAAGCTGGCCCAGCGCTACTTGACGAGTAAGCGGCTTCCAGATTCAGCGATTGATCTGCTTGA
TGAAGCTAGTGCGATGGTACAAAGCATGGTTAAAAAGACGCAGCCTGACTTTATAACGCCGCTTGATCAAGCCCTGCTTG
ATGGTGATATGAGCAAGGTGTCAGCCCTTTTAGCCAAAGAGGATAAGCAACCAAAGCTAAAACCAACAGCAGTTACTGAA
GATGATATGTTACACACCTTAAGCAAGCTATCAGGTATTCCCCTAGAAAAACTAACTCAGGCGGATAGTAAAAAATATCT
GAATCTGGAAAAGGAATTGCATAAGCGTGTTGTTGGTCAGGAAATGGCTGTTTCTGCTATTGCACGAGCCATTCGTCGTA
ACCAGTCAGGCATTCGCACAGGCAGGCGTCCGATTGGCTCCTTTATGTTTCTTGGTCCAACTGGTGTCGGAAAAACAGAG
CTAGCAAAGGCCTTGGCCGAATTACTCTTTGATGATGAGTCAGCCCTTATTCGTTTTGATATGTCTGAGTACATGGAAAA
ATTTGCAGCCTCCCGTCTTAATGGGGCTCCTCCTGGCTATGTTGGCTATGATGAGGGAGGAGAGCTAACCGAAAAGGTTA
GAAATAAGCCTTATGCCGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCACCCAGACATCTTTAATATCCTGCTGCAGGTC
CTTGATGATGGTATGTTAACAGATAGTCGTGGACGTAAGGTTGATTTTTCAAACACGATTATTATCATGACGAGCAACCT
AGGAGCAACTGCTCTAAGAGATGATAAGACGGTTGGATTTGGCGCTAAAGCGATCGGTCATGACCATCAAGCAATGGAAA
AGCGTATTTTAGAGGAATTGAAAAAGGCTTATCGGCCTGAATTTATCAACAGAATTGATGAAAAGGTGGTCTTCCACAGC
CTAACACAGGAAAACATGCGTGATGTGGTCAAAATTATGGTTAAGCCGCTGATTGCAGCCTTGGCAGAAAAGCATATTAG
CCTTAAGTTCCAGCCATCAGCTCTCAAGTACTTGTCTGAAGCTGGTTACGATGTTGAAATGGGGGCTCGCCCACTTCGTC
GCACCTTGCAAACAGAGGTTGAGGACAGGTTAGCAGAATTAATGCTGTCAGGAGAGTTATCAAGCGGTCAAAGCCTCAAG
ATTGGTGTATCACATGGGAAGTTAGCTTTTGATATTGCTTGA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)

AAA lid domain (AAA_lid_9)

(374-457)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(95-131)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-51)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-800)

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

74.539

100

0.745
  clpC Streptococcus thermophilus LMD-9

72.304

100

0.726
  clpC Streptococcus thermophilus LMG 18311

72.059

100

0.723
  clpC Streptococcus pneumoniae Rx1

65.971

100

0.661
  clpC Streptococcus pneumoniae D39

65.971

100

0.661
  clpC Streptococcus pneumoniae TIGR4

65.848

100

0.659
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.746

100

0.502
  clpC Bacillus subtilis subsp. subtilis str. 168

43.832

100

0.45
  clpE Streptococcus mutans UA159

45.356

79.459

0.36

Multiple sequence alignment