Detailed information NTG0313551

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: D2E16_RS11135
• Genome accession: NZ_CP032064
• Coordinates: 2301121..2303574 (-)
• Length: 817 a.a.
• NCBI ID: WP_192369500.1
• Uniprot ID: -
• Organism: Streptococcus suis strain YSJ17
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 2296121..2308574

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D2E16_RS11120 (D2E16_11475)	hslO	2298552..2299418 (+)	867	WP_044687505.1	Hsp33 family molecular chaperone HslO	-
D2E16_RS11125 (D2E16_11480)	dusB	2299411..2300415 (+)	1005	WP_192369502.1	tRNA dihydrouridine synthase DusB	-
D2E16_RS11130 (D2E16_11485)	-	2300511..2301002 (-)	492	WP_192369501.1	adenylyltransferase/cytidyltransferase family protein	-
D2E16_RS11135 (D2E16_11490)	clpC	2301121..2303574 (-)	2454	WP_192369500.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
D2E16_RS11140 (D2E16_11495)	-	2303576..2304034 (-)	459	WP_192369499.1	CtsR family transcriptional regulator	-
D2E16_RS11145 (D2E16_11500)	-	2304310..2304654 (+)	345	WP_192369498.1	thioredoxin domain-containing protein	-
D2E16_RS11150 (D2E16_11505)	-	2304648..2305274 (+)	627	WP_125065377.1	GNAT family acetyltransferase	-
D2E16_RS11155 (D2E16_11520)	tsf	2305824..2306864 (-)	1041	WP_174852296.1	translation elongation factor Ts	-
D2E16_RS11160 (D2E16_11525)	rpsB	2307020..2307796 (-)	777	WP_012775356.1	30S ribosomal protein S2	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90720.34 Da
• Isoelectric Point: 6.0442

>NTDB_id=313551 D2E16_RS11135 WP_192369500.1 2301121..2303574(-) (clpC) [Streptococcus suis strain YSJ17]
MKISKGLQAVYEDAQLIAQRYNCDYLETWHLLLAFVINPDTLAGSVLAEYPADIADYEHATFVVTNRLYREDELTRIALL
PSSKKMGDLQVFSEKIAEIVKSKELGTEHLFMGMLLDKRSTASQILDKVGFRFEDSDDKIRFLDLRKNLEAKAGFTKEHL
KAIRLLMKGEKTKPNTMGNMMGMPQPQSGGLEEYTRDLTALAREGMMEPVIGRDAEISRMIQILSRKTKNNPVLVGDAGV
GKTALAFGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQDEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFERYHRVRIGQAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEEAGLTSIDKALMNRKYKTVSKLLLIAQEAENQNANYDLEV
TDEDILETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTESHMQDVVKVMVKPLLAVTAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLTTGST
LKVGVKGEEIKFDVVKG

Nucleotide

• Length: 2454 bp

>NTDB_id=313551 D2E16_RS11135 WP_192369500.1 2301121..2303574(-) (clpC) [Streptococcus suis strain YSJ17]
ATGAAGATTTCAAAAGGTTTACAGGCAGTTTATGAAGATGCCCAACTGATTGCGCAACGGTACAATTGCGATTACTTGGA
GACTTGGCATTTGTTACTGGCATTTGTTATCAATCCAGATACTCTTGCAGGTTCTGTCTTGGCAGAATACCCTGCGGATA
TTGCTGATTATGAGCACGCGACATTTGTGGTTACGAACCGTCTTTATCGAGAGGATGAATTGACGAGGATTGCTTTATTA
CCATCTTCCAAGAAAATGGGGGACTTGCAGGTTTTTTCAGAAAAAATTGCAGAAATTGTAAAGAGTAAGGAGCTTGGGAC
GGAGCATTTGTTTATGGGGATGCTGTTAGATAAGCGTTCAACAGCATCGCAGATTTTAGATAAGGTTGGTTTCCGATTCG
AGGACTCAGATGATAAGATTCGCTTTTTGGATTTGCGAAAAAATTTGGAAGCTAAAGCAGGGTTTACCAAAGAACACCTT
AAGGCAATCCGGCTCTTGATGAAGGGGGAGAAGACCAAGCCAAATACGATGGGAAACATGATGGGCATGCCCCAACCGCA
GAGCGGTGGTTTGGAAGAGTACACTCGTGATCTGACTGCTTTGGCTCGTGAAGGCATGATGGAGCCGGTTATTGGTCGCG
ATGCAGAAATCTCGCGGATGATTCAAATCTTATCGCGTAAAACCAAGAACAATCCGGTCTTGGTTGGGGATGCCGGTGTC
GGCAAAACGGCGCTTGCCTTTGGTCTTGCTCAGCGTGTGGCAGCTGGGGATGTCCCTGTTAGCTTGGCCAAGATGCGGGT
TTTAGAGCTTGATTTGATGAATGTGATCGCAGGGACGCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ACGACATCGAGGAAGATGGTCAGGTCATCCTTTTCATCGATGAGTTGCATACCATTATGGGTTCTGGCTCAGGGATTGAT
TCGACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTGGCTCGTGGTACCCTACGTACAGTAGGTGCTACGACACAAGA
TGAGTACCAAAAGCATATTGAGAAAGATGCAGCCTTGGTCCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTTG
AGGACAGTATTGCCATTTTGACAGGGCTTAAAGGTACTTTTGAGAGATACCACAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTGCCAGATTCAGCCATTGATTTGCTAGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGTCAGGCAGAGGAAGCGGGTCTGACGAGCATTGACAAGGCCTTGATGAATA
GAAAATATAAAACTGTCAGCAAGCTCTTGCTTATAGCTCAGGAAGCAGAAAATCAGAATGCCAACTATGACTTAGAAGTG
ACGGATGAAGATATTTTAGAAACCCTCAGTCGTTTGTCAGGTATCCCAGTGGCCAAGCTCAGCCAATCAGATACTAAGAA
GTACCTGAATCTGGAAGCAGAATTGCACAAGCGTGTGATTGGCCAAGAAGAAGCGATTTCTGCAGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGCTCCTTTATGTTCTTAGGACCAACTGGTGTCGGTAAG
ACAGAGCTTGCTAAAGCCTTGGCAGAGGTTCTCTTTGATGACGAATCAGCCCTTATCCGTTTTGACATGTCCGAATACAT
GGAGAAATTTGCAGCCAGCCGTTTAAACGGTGCGCCTCCGGGCTATGTGGGTTATGAAGAAGGTGGCGAATTGACGGAAA
AAGTTCGTAACAAACCTTATTCTGTTCTTCTCTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTCCTCTTG
CAGGTCTTGGATGATGGTGTTTTGACAGATAGCAAAGGACGTAAGGTTGATTTCTCAAATACCATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGGGATGATAAGACAGTTGGCTTTGGTGCCCTTGATTTATCGAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAACCGTATTGACGAGAAAGTTGTCTTC
CATAGCTTGACAGAATCCCATATGCAGGATGTTGTCAAGGTCATGGTTAAACCTTTGTTGGCTGTAACAGCTGAGAAAGG
AATTACCCTTAAACTGCAACCGTCAGCCCTTAAGTTATTAGCTAAACAAGGTTACGATCCAGAAATGGGAGCTCGTCCTC
TTCGTAGGCTCTTACAAACCAAATTGGAAGATCCGTTGGCAGAAATGTTGCTCCGTGGTGACTTGACTACTGGTTCGACC
TTGAAGGTTGGGGTCAAGGGCGAAGAGATCAAGTTTGATGTGGTAAAGGGATAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• AAA lid domain (AAA_lid_9) (372-453)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (101-131)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-58)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	71.288	99.755	0.711
clpC	Streptococcus pneumoniae D39	71.288	99.755	0.711
clpC	Streptococcus pneumoniae TIGR4	71.288	99.755	0.711
clpC	Streptococcus mutans UA159	65.845	99.266	0.654
clpC	Streptococcus thermophilus LMG 18311	65.037	100	0.651
clpC	Streptococcus thermophilus LMD-9	64.792	100	0.649
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.736	100	0.496
clpC	Bacillus subtilis subsp. subtilis str. 168	43.818	100	0.447