Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   D2E16_RS02730 Genome accession   NZ_CP032064
Coordinates   548400..550628 (-) Length   742 a.a.
NCBI ID   WP_015646546.1    Uniprot ID   A0A0M9FFN0
Organism   Streptococcus suis strain YSJ17     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 543400..555628
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D2E16_RS02700 (D2E16_02790) - 545101..545286 (+) 186 WP_002942274.1 hypothetical protein -
  D2E16_RS02705 (D2E16_02795) tnpB 545267..545617 (+) 351 WP_002941575.1 IS66 family insertion sequence element accessory protein TnpB -
  D2E16_RS02710 (D2E16_02800) - 545669..545875 (+) 207 WP_002941576.1 hypothetical protein -
  D2E16_RS02715 (D2E16_02805) - 545829..547181 (+) 1353 WP_105159391.1 IS66-like element short variant transposase -
  D2E16_RS02720 (D2E16_02810) - 547390..547698 (-) 309 WP_002938710.1 DUF1827 family protein -
  D2E16_RS02725 (D2E16_02815) - 547753..548214 (-) 462 WP_192370192.1 NUDIX hydrolase -
  D2E16_RS02730 (D2E16_02820) clpE 548400..550628 (-) 2229 WP_015646546.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  D2E16_RS02735 (D2E16_02825) - 550852..551082 (+) 231 WP_002938704.1 DUF1797 family protein -
  D2E16_RS02740 (D2E16_02830) - 551209..551898 (+) 690 WP_044691021.1 amino acid ABC transporter permease -
  D2E16_RS02745 (D2E16_02835) - 551891..552625 (+) 735 WP_002943067.1 amino acid ABC transporter ATP-binding protein -
  D2E16_RS02750 (D2E16_02840) - 552859..553707 (+) 849 WP_024375752.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  D2E16_RS02755 (D2E16_02845) - 553919..555208 (-) 1290 WP_194472458.1 IS4 family transposase -
  D2E16_RS02760 (D2E16_02850) - 555451..555603 (+) 153 WP_099870668.1 YSIRK-type signal peptide-containing protein -

Sequence

Protein


Download         Length: 742 a.a.        Molecular weight: 82596.95 Da        Isoelectric Point: 5.2782

>NTDB_id=313522 D2E16_RS02730 WP_015646546.1 548400..550628(-) (clpE) [Streptococcus suis strain YSJ17]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGGYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide


Download         Length: 2229 bp        

>NTDB_id=313522 D2E16_RS02730 WP_015646546.1 548400..550628(-) (clpE) [Streptococcus suis strain YSJ17]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAGCAGCAGGTAGA
CCTCTGTCACAACTGCTACCAAATCATGAAAACAGACCCTAATAATGCCATCCTACGTGGGTTGGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTTTTCAATCACCTAGGTGGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCCACTCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAAATTACCCGTGTCATCGAAATTCTAAACCGTCGTACAAAAAACAACCCTGTTCTTATCGGTGAGCCTGGTGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTGCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGCGGACAATTTGAAGAACGTATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGTTCTGCAGGCGAT
GGCAACATGGATGCTGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAGCTAGTCGGTGCAACGACGCTCAA
CGAATACCGTATTATCGAAAAAGATGCCGCCCTAGAGCGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACCATTACCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCGGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAGGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAAGAAATTGACCAACGCCTAATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAAAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAGAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTCGTGAACCTCGCTAGTGACTTAAAAGCCCATGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCAATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCGGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTACTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGGCGGACAGT
CAGCTTCAAAGATACCATCATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGC
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCAGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(476-639)

AAA lid domain (AAA_lid_9)

(291-389)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(647-721)

ATPase family associated with various cellular activities (AAA) (AAA)

(153-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FFN0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

82.361

100

0.837
  clpE Streptococcus pneumoniae D39

82.361

100

0.837
  clpE Streptococcus pneumoniae R6

82.361

100

0.837
  clpE Streptococcus pneumoniae TIGR4

82.361

100

0.837
  clpE Streptococcus mutans UA159

82.377

100

0.832
  clpC Lactococcus lactis subsp. cremoris KW2

77.655

97.709

0.759
  clpC Bacillus subtilis subsp. subtilis str. 168

52.462

87.601

0.46
  clpC Streptococcus mutans UA159

48.558

84.097

0.408
  clpC Streptococcus thermophilus LMD-9

48.248

84.636

0.408
  clpC Streptococcus thermophilus LMG 18311

47.93

84.636

0.406
  clpC Streptococcus pneumoniae TIGR4

47.84

84.232

0.403
  clpC Streptococcus pneumoniae Rx1

47.84

84.232

0.403
  clpC Streptococcus pneumoniae D39

47.84

84.232

0.403
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.815

84.636

0.396

Multiple sequence alignment