Detailed information NTG0031347

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SEZ_RS00280
• Genome accession: NC_011134
• Coordinates: 47940..48854 (+)
• Length: 304 a.a.
• NCBI ID: WP_012514714.1
• Uniprot ID: A0AAW3GQI0
• Organism: Streptococcus equi subsp. zooepidemicus MGCS10565
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 42940..53854

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SEZ_RS00260 (Sez_0031)	purE	44103..44591 (+)	489	WP_012514711.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
SEZ_RS00265 (Sez_0032)	purK	44578..45669 (+)	1092	WP_012514712.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
SEZ_RS00270 (Sez_0033)	-	45679..45903 (+)	225	WP_012514713.1	hypothetical protein	-
SEZ_RS10105	-	45927..45998 (+)	72	Protein_34	hypothetical protein	-
SEZ_RS00275 (Sez_0034)	purB	46348..47641 (+)	1294	Protein_35	adenylosuccinate lyase	-
SEZ_RS00280 (Sez_0036)	comR	47940..48854 (+)	915	WP_012514714.1	XRE family transcriptional regulator	Regulator
SEZ_RS00285 (Sez_0037)	ruvB	49069..50070 (+)	1002	WP_012514715.1	Holliday junction branch migration DNA helicase RuvB	-
SEZ_RS00290 (Sez_0039)	-	50356..50814 (+)	459	WP_012514717.1	low molecular weight protein-tyrosine-phosphatase	-
SEZ_RS00295 (Sez_0040)	-	50820..51221 (+)	402	WP_012514718.1	MORN repeat-containing protein	-
SEZ_RS00300 (Sez_0041)	-	51218..52998 (+)	1781	Protein_40	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35823.41 Da
• Isoelectric Point: 4.5517

>NTDB_id=31347 SEZ_RS00280 WP_012514714.1 47940..48854(+) (comR) [Streptococcus equi subsp. zooepidemicus MGCS10565]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVYIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKSNKLEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDIEMAKKCYDKACLFAQLTGDQYLEKKLREEWGKDIKRYQ

Nucleotide

• Length: 915 bp

>NTDB_id=31347 SEZ_RS00280 WP_012514714.1 47940..48854(+) (comR) [Streptococcus equi subsp. zooepidemicus MGCS10565]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTTCGGTATCAGAAAAAAATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTGGCACGAATAGAACTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTATATTG
CTAAGGCTCTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTGCCTAAGCGTTATAAAGAACTTAAA
TATTTGATTTTAAGAACGCCGACCTATATGGATGATGACAAATTAAAGCTGCGAGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGACCAGTTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACCG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAGACAAAAAGCAAGACTCAATTTAGAGAGAATGAC
CTTATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAGCAATAAGCTGGAGATTCTTGAGAAGGTTATTGTGCTTAGTCAAAAAATTATTCTC
AAGACTCAGGATTTCAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATACGCTTTAATGAAGAAAAAAGACATAGA
AATGGCCAAAAAATGCTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTGGAAAAGAAATTGAGAG
AAGAATGGGGTAAAGATATAAAACGATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (10-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.257	99.671	0.74
comR	Streptococcus pyogenes MGAS315	54.485	99.013	0.539
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	51.379	95.395	0.49
comR	Streptococcus mutans UA159	49.498	98.355	0.487
comR	Streptococcus suis P1/7	38.591	98.026	0.378
comR	Streptococcus suis 05ZYH33	38.644	97.039	0.375
comR	Streptococcus suis D9	37.037	97.697	0.362