Detailed information NTG0313045

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: AhaeAN43_RS04945
• Genome accession: NZ_CP031976
• Coordinates: 1050965..1053403 (+)
• Length: 812 a.a.
• NCBI ID: WP_160126531.1
• Uniprot ID: A0A857II28
• Organism: Acinetobacter haemolyticus strain AN43
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	1050195..1058197	1050965..1053403	within	0

Gene organization within MGE regions

Location: 1050195..1058197

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AhaeAN43_RS04940 (AhaeAN43_05005)	lolD	1050195..1050881 (+)	687	WP_075315118.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
AhaeAN43_RS04945 (AhaeAN43_05010)	comA/comEC	1050965..1053403 (+)	2439	WP_160126531.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AhaeAN43_RS04950 (AhaeAN43_05015)	-	1053392..1054348 (-)	957	WP_160126532.1	lysophospholipid acyltransferase family protein	-
AhaeAN43_RS04955 (AhaeAN43_05020)	sppA	1054488..1055510 (+)	1023	WP_005084487.1	signal peptide peptidase SppA	-
AhaeAN43_RS04960 (AhaeAN43_05025)	-	1055657..1056454 (+)	798	WP_005084488.1	alpha/beta fold hydrolase	-
AhaeAN43_RS04965 (AhaeAN43_05030)	purN	1056501..1057130 (-)	630	WP_171456280.1	phosphoribosylglycinamide formyltransferase	-
AhaeAN43_RS04970 (AhaeAN43_05035)	purM	1057127..1058197 (-)	1071	WP_005089611.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 812 a.a.
• Molecular weight: 93195.26 Da
• Isoelectric Point: 9.0573

>NTDB_id=313045 AhaeAN43_RS04945 WP_160126531.1 1050965..1053403(+) (comA/comEC) [Acinetobacter haemolyticus strain AN43]
MLKIILLGWVAGIALMGMHFPIITSTWWLWLIIAFAIFGFGFYWKKQYFHYPTYKALLLISATWALFCTGYHYADIQLQQ
RLIFKEQNAETFEAIVYIKKISELNENGEKQVAEVLNRHAQSVNWFLHLRKEKDTSKVEPEFQLGHYYRVSGQIRPAHSY
AVPGAFDLEKWFLQQNVQSGFSVRNIQPIHEDELYQLGYHHHLQQQKSHWAIFLLAVEKKRLAFRQMLQASAFQHKGLLL
ALLTGDESLLSDAVKQQFQHLGISHLLAISGPHVLVFALILTWSLQKLIQRYCPSIYLKQPRQLLLLLPFIFSVLLYVAF
VGFEIPAMRTLLTVSIVSTFMCLRQSIQAFSVLVYSASLLLVLDPFSILSAAFWLSYGACFILIRIYQTIIQLPQNVNLT
FKQKMIWGSHILIESQWKIFVALLPLVLIFFQQVSWFAPLTNLIAIPLLGACIVPLDILAACVWLIIPTLGQWLFQMNDA
FLSFLMLILDVLQSISPQLYGISFTPWMMVSLIIGIFLLFLPRGVVPKLWAAVCFLPILWGVKAQPEALHVLDVGQGQAI
LVQHSKGNLLIDTGGSFDEAKFSMGERVVIPFLRQQGIRRLEHVVLSHLDQDHSGAFTSIQNSFEIDLVQSNEKHEKMQF
KENFSFCQQGQQWSFPNINIQVLFPRANELSYAKYQKNEYSCVLYVQFLDAQTYQNFLIMGDAGWETEYKLLQQYPDLKV
DVLILGHHGSKHSSAYEFLASLKPKLTIASAGFNNRYGHPSQEVLKRLQHLNIPILNTADAGTISFMMNNHDGVLLQHRK
KRKWLSKNSLSN

Nucleotide

• Length: 2439 bp

>NTDB_id=313045 AhaeAN43_RS04945 WP_160126531.1 1050965..1053403(+) (comA/comEC) [Acinetobacter haemolyticus strain AN43]
ATGCTAAAAATTATTTTATTGGGGTGGGTTGCGGGTATCGCACTTATGGGAATGCATTTCCCGATCATTACATCTACATG
GTGGCTTTGGCTGATTATTGCATTCGCGATCTTTGGTTTCGGATTTTATTGGAAAAAGCAGTATTTTCATTATCCTACTT
ATAAAGCCTTGCTTTTAATCAGTGCGACTTGGGCATTATTTTGCACAGGTTATCATTATGCTGATATTCAATTACAACAA
CGTCTTATTTTTAAAGAACAAAATGCTGAAACATTTGAAGCCATTGTTTATATCAAAAAGATCAGTGAACTGAATGAAAA
TGGCGAGAAACAAGTTGCTGAGGTTTTGAATCGACATGCGCAAAGTGTGAATTGGTTTCTTCATTTAAGAAAAGAAAAAG
ACACATCTAAAGTAGAACCAGAATTTCAATTGGGTCATTACTATCGTGTATCTGGGCAAATTCGACCCGCCCATAGTTAT
GCCGTCCCTGGTGCATTCGATCTGGAAAAATGGTTTTTACAACAAAATGTGCAGTCGGGATTTTCTGTACGAAATATTCA
GCCTATTCATGAAGATGAACTCTATCAGCTGGGTTATCATCATCATTTGCAGCAACAAAAATCTCATTGGGCCATATTCT
TATTAGCTGTTGAAAAAAAGCGTTTGGCTTTTCGACAAATGCTACAGGCATCAGCATTCCAACATAAAGGGTTGCTATTG
GCTTTGCTCACAGGGGATGAGAGTCTTTTATCTGATGCCGTAAAACAACAATTTCAACACCTTGGGATTTCACATTTATT
GGCTATTTCTGGACCACATGTGTTGGTATTTGCATTGATACTGACTTGGTCATTACAAAAGTTGATTCAGCGCTACTGCC
CAAGCATCTATTTGAAGCAACCTCGACAATTACTACTATTGTTACCCTTTATCTTTAGTGTCTTGCTATATGTGGCATTT
GTTGGTTTTGAGATTCCAGCAATGAGAACATTATTAACCGTTAGCATTGTCAGTACTTTTATGTGCTTAAGACAGTCGAT
TCAGGCATTTAGTGTGTTGGTTTATAGTGCGAGCTTATTGTTAGTTTTAGATCCATTTAGCATTTTATCTGCTGCATTTT
GGTTATCTTATGGCGCGTGTTTTATTTTGATAAGAATCTATCAGACGATTATACAGTTACCACAAAATGTAAACTTAACA
TTTAAACAAAAAATGATCTGGGGTAGTCATATTCTGATTGAATCGCAATGGAAAATTTTTGTCGCGTTATTGCCTTTGGT
TTTGATTTTCTTTCAGCAAGTTTCATGGTTTGCCCCCTTAACGAATCTTATTGCTATCCCATTGTTAGGTGCTTGTATTG
TTCCTTTAGATATTCTAGCTGCATGTGTGTGGTTAATTATTCCTACATTAGGGCAGTGGTTATTTCAAATGAATGATGCG
TTTTTGTCATTCTTGATGCTGATTTTAGATGTACTTCAATCGATTTCGCCGCAGTTGTATGGGATAAGTTTCACTCCTTG
GATGATGGTGAGTTTAATTATCGGTATTTTTCTATTGTTCTTGCCTAGAGGTGTCGTTCCAAAGCTTTGGGCTGCTGTCT
GTTTCTTACCGATATTATGGGGTGTAAAAGCTCAACCCGAAGCATTGCATGTATTGGATGTTGGGCAAGGCCAAGCAATC
TTGGTACAACATTCAAAAGGTAATCTCCTGATTGATACTGGTGGATCATTTGATGAAGCCAAATTTAGTATGGGGGAACG
TGTGGTTATTCCATTTCTACGTCAACAGGGTATTCGGCGATTGGAGCATGTTGTGTTATCGCATTTGGATCAAGATCATA
GTGGCGCATTTACGTCGATTCAAAATAGTTTTGAAATTGATTTGGTTCAATCGAATGAAAAGCATGAAAAAATGCAATTT
AAGGAGAATTTTTCATTTTGCCAACAAGGTCAACAGTGGTCATTTCCAAACATCAACATCCAAGTTTTATTTCCTCGAGC
CAATGAATTGAGCTATGCGAAATATCAGAAAAATGAATATTCTTGTGTGCTCTATGTGCAATTTTTAGATGCTCAAACTT
ATCAGAACTTTTTGATTATGGGGGATGCAGGCTGGGAAACCGAATATAAATTGTTACAGCAGTATCCAGATTTAAAAGTC
GATGTGTTAATTCTTGGTCATCATGGCAGTAAGCATAGCTCTGCTTACGAATTTTTGGCAAGCCTCAAGCCCAAACTTAC
AATTGCTTCTGCGGGATTTAATAATCGTTACGGACATCCCAGTCAGGAGGTTTTAAAACGATTGCAGCACTTAAATATTC
CAATATTAAATACAGCAGATGCGGGTACGATTAGCTTTATGATGAATAATCATGATGGGGTGTTGCTACAGCATCGAAAA
AAAAGAAAATGGTTATCCAAAAATAGCCTAAGTAATTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (242-523)

• Domain of unknown function (DUF4131) (DUF4131) (23-187)

• Metallo-beta-lactamase superfamily (Lactamase_B) (553-626)

3D structure

• AlphaFold DB: A0A857II28

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	54.444	99.754	0.543
comA/comEC	Acinetobacter baumannii strain A118	53.951	99.754	0.538
comA/comEC	Acinetobacter baylyi ADP1	50.123	99.754	0.5