Detailed information NTG0312783

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LL223_RS12095
• Genome accession: NZ_CP031926
• Coordinates: 2346496..2347524 (-)
• Length: 342 a.a.
• NCBI ID: WP_010906347.1
• Uniprot ID: A0AAP4JQE3
• Organism: Lactococcus lactis subsp. lactis strain 223
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2341496..2352524

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LL223_RS12070 (LL223_2309)	-	2341782..2342279 (-)	498	WP_021214977.1	nitroreductase family protein	-
LL223_RS12075 (LL223_2310)	-	2342266..2342475 (-)	210	WP_003132661.1	hypothetical protein	-
LL223_RS12080 (LL223_2311)	-	2342472..2343299 (-)	828	WP_010906344.1	radical SAM protein	-
LL223_RS12085 (LL223_2312)	-	2343292..2345415 (-)	2124	WP_010906345.1	radical SAM protein	-
LL223_RS12090 (LL223_2313)	-	2345518..2346375 (-)	858	WP_010906346.1	transcriptional regulator	-
LL223_RS12095 (LL223_2314)	sepM	2346496..2347524 (-)	1029	WP_010906347.1	SepM family pheromone-processing serine protease	Regulator
LL223_RS12100 (LL223_2315)	coaD	2347511..2348008 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
LL223_RS12105 (LL223_2316)	rsmD	2348056..2348595 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LL223_RS12110 (LL223_2317)	-	2348766..2349986 (-)	1221	WP_003132654.1	MFS transporter	-
LL223_RS12115 (LL223_2318)	lmrP	2350070..2351296 (-)	1227	WP_205288537.1	multidrug efflux MFS transporter LmrP	-
LL223_RS12120 (LL223_2319)	-	2351484..2351978 (+)	495	WP_010906351.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37379.98 Da
• Isoelectric Point: 9.9183

>NTDB_id=312783 LL223_RS12095 WP_010906347.1 2346496..2347524(-) (sepM) [Lactococcus lactis subsp. lactis strain 223]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKTAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=312783 LL223_RS12095 WP_010906347.1 2346496..2347524(-) (sepM) [Lactococcus lactis subsp. lactis strain 223]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTACAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGTGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGCAGCAACAATTACCTTGGAGCCAAAACCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491