Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGG   Type   Machinery gene
Locus tag   LL223_RS11630 Genome accession   NZ_CP031926
Coordinates   2259687..2259971 (-) Length   94 a.a.
NCBI ID   WP_010906314.1    Uniprot ID   A0AAC9R304
Organism   Lactococcus lactis subsp. lactis strain 223     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2249457..2325982 2259687..2259971 within 0


Gene organization within MGE regions


Location: 2249457..2325982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LL223_RS11580 (LL223_2216) - 2249462..2251288 (-) 1827 WP_205288535.1 acyltransferase family protein -
  LL223_RS11585 (LL223_2217) - 2251390..2253621 (-) 2232 WP_003129980.1 PBP1A family penicillin-binding protein -
  LL223_RS11590 (LL223_2218) - 2253930..2254565 (-) 636 WP_010906307.1 DUF421 domain-containing protein -
  LL223_RS11595 (LL223_2219) - 2254582..2255013 (-) 432 WP_010906308.1 DUF3290 domain-containing protein -
  LL223_RS11600 (LL223_2220) - 2255127..2255504 (-) 378 WP_003129983.1 pyridoxamine 5'-phosphate oxidase family protein -
  LL223_RS11605 (LL223_2221) - 2255709..2256575 (+) 867 WP_010906309.1 RluA family pseudouridine synthase -
  LL223_RS11610 (LL223_2222) - 2256614..2257423 (-) 810 WP_010906310.1 metal ABC transporter permease -
  LL223_RS11615 (LL223_2223) - 2257416..2258153 (-) 738 WP_010906311.1 metal ABC transporter ATP-binding protein -
  LL223_RS11620 (LL223_2224) - 2258330..2259172 (-) 843 WP_010906312.1 metal ABC transporter substrate-binding protein -
  LL223_RS11625 (LL223_2225) - 2259169..2259606 (-) 438 WP_010906313.1 zinc-dependent MarR family transcriptional regulator -
  LL223_RS11630 (LL223_2226) comGG 2259687..2259971 (-) 285 WP_010906314.1 competence type IV pilus minor pilin ComGG Machinery gene
  LL223_RS11635 (LL223_2227) comGF 2260010..2260456 (-) 447 WP_031296844.1 competence type IV pilus minor pilin ComGF Machinery gene
  LL223_RS11640 (LL223_2228) comGE 2260419..2260715 (-) 297 WP_010906316.1 competence type IV pilus minor pilin ComGE Machinery gene
  LL223_RS11645 (LL223_2229) comGD 2260687..2261085 (-) 399 WP_021214886.1 competence type IV pilus minor pilin ComGD Machinery gene
  LL223_RS11650 (LL223_2230) comGC 2261078..2261347 (-) 270 WP_023349160.1 competence type IV pilus major pilin ComGC Machinery gene
  LL223_RS11655 (LL223_2231) - 2261494..2262018 (-) 525 WP_014570795.1 GNAT family N-acetyltransferase -
  LL223_RS11660 (LL223_2232) - 2262097..2262876 (-) 780 WP_058147788.1 peptidoglycan amidohydrolase family protein -
  LL223_RS11665 (LL223_2233) - 2262876..2263175 (-) 300 WP_031559226.1 phage holin -
  LL223_RS11670 (LL223_2234) - 2263188..2263538 (-) 351 WP_023349296.1 hypothetical protein -
  LL223_RS11675 (LL223_2235) - 2263558..2265612 (-) 2055 WP_373270652.1 collagen-like protein -
  LL223_RS11680 (LL223_2236) - 2265596..2265769 (-) 174 WP_086383510.1 hypothetical protein -
  LL223_RS11685 (LL223_2237) - 2265769..2266890 (-) 1122 WP_086383554.1 hypothetical protein -
  LL223_RS11690 (LL223_2238) - 2266907..2268700 (-) 1794 WP_031297170.1 phage tail protein -
  LL223_RS11695 (LL223_2239) - 2268697..2270217 (-) 1521 WP_058147722.1 distal tail protein Dit -
  LL223_RS11700 (LL223_2240) - 2270227..2272836 (-) 2610 WP_023349195.1 hypothetical protein -
  LL223_RS11705 (LL223_2241) - 2272826..2273533 (-) 708 WP_014570560.1 Gp15 family bacteriophage protein -
  LL223_RS11710 (LL223_2242) - 2273549..2273956 (-) 408 WP_003131323.1 hypothetical protein -
  LL223_RS11715 (LL223_2243) - 2274013..2274489 (-) 477 WP_014570559.1 phage tail tube protein -
  LL223_RS11720 (LL223_2244) - 2274500..2274934 (-) 435 WP_003131321.1 minor capsid protein -
  LL223_RS11725 (LL223_2245) - 2274934..2275263 (-) 330 WP_003131320.1 hypothetical protein -
  LL223_RS11730 (LL223_2246) - 2275260..2275604 (-) 345 WP_003131319.1 putative minor capsid protein -
  LL223_RS11735 (LL223_2247) - 2275594..2275995 (-) 402 WP_014570556.1 hypothetical protein -
  LL223_RS11740 (LL223_2248) - 2276069..2276305 (-) 237 WP_023349196.1 Ig-like domain-containing protein -
  LL223_RS11745 (LL223_2249) - 2276334..2277251 (-) 918 WP_023349197.1 phage capsid protein -
  LL223_RS11750 (LL223_2250) - 2277266..2278318 (-) 1053 WP_023349198.1 XkdF-like putative serine protease domain-containing protein -
  LL223_RS11755 (LL223_2251) - 2278334..2279164 (-) 831 WP_023349199.1 phage minor head protein -
  LL223_RS11760 (LL223_2252) - 2279157..2280686 (-) 1530 WP_023349200.1 phage portal protein -
  LL223_RS11765 (LL223_2253) terL 2280699..2282150 (-) 1452 WP_023349201.1 phage terminase large subunit -
  LL223_RS11770 (LL223_2254) - 2282131..2282628 (-) 498 WP_023349202.1 hypothetical protein -
  LL223_RS11775 (LL223_2255) - 2282657..2283814 (-) 1158 WP_023349203.1 DNA modification methylase -
  LL223_RS11785 (LL223_2256) - 2284291..2284713 (-) 423 WP_023349204.1 RinA family protein -
  LL223_RS11790 (LL223_2257) - 2285061..2285306 (-) 246 WP_023349207.1 hypothetical protein -
  LL223_RS11795 (LL223_2258) - 2285328..2285825 (-) 498 WP_086383531.1 hypothetical protein -
  LL223_RS11800 (LL223_2259) - 2285828..2286247 (-) 420 WP_086383533.1 dUTP diphosphatase -
  LL223_RS11805 (LL223_2260) - 2286244..2286549 (-) 306 WP_023349170.1 hypothetical protein -
  LL223_RS11810 (LL223_2261) - 2286546..2287049 (-) 504 WP_023349171.1 DUF1642 domain-containing protein -
  LL223_RS11815 (LL223_2262) - 2287042..2287437 (-) 396 WP_058147723.1 YopX family protein -
  LL223_RS11820 (LL223_2263) - 2287629..2287835 (-) 207 WP_014570535.1 hypothetical protein -
  LL223_RS11825 (LL223_2264) - 2287943..2288353 (-) 411 WP_014570810.1 hypothetical protein -
  LL223_RS11830 (LL223_2265) - 2288366..2288608 (-) 243 WP_023349173.1 L-rhamnose isomerase -
  LL223_RS11835 (LL223_2266) - 2288601..2289524 (-) 924 WP_023349174.1 phage replisome organizer N-terminal domain-containing protein -
  LL223_RS11840 (LL223_2267) - 2289788..2290714 (-) 927 WP_014570813.1 RecT family recombinase -
  LL223_RS11845 (LL223_2268) - 2290711..2291544 (-) 834 WP_023349175.1 hypothetical protein -
  LL223_RS11850 (LL223_2269) - 2291647..2291895 (-) 249 WP_014570815.1 hypothetical protein -
  LL223_RS11855 (LL223_03265) - 2291909..2292031 (-) 123 WP_023164646.1 hypothetical protein -
  LL223_RS11860 (LL223_2270) - 2292028..2292210 (-) 183 WP_023349176.1 hypothetical protein -
  LL223_RS11865 (LL223_2271) - 2292274..2292483 (-) 210 WP_023349177.1 helix-turn-helix transcriptional regulator -
  LL223_RS11870 (LL223_2272) - 2292674..2293096 (+) 423 WP_023349178.1 helix-turn-helix transcriptional regulator -
  LL223_RS11875 (LL223_2273) - 2293107..2293691 (+) 585 WP_101916262.1 hypothetical protein -
  LL223_RS11880 (LL223_2274) - 2293745..2294407 (+) 663 WP_023349180.1 SHOCT domain-containing protein -
  LL223_RS11885 (LL223_2275) - 2294522..2295979 (+) 1458 WP_058147724.1 recombinase family protein -
  LL223_RS11890 (LL223_03270) - 2295976..2296116 (-) 141 WP_228777719.1 hypothetical protein -
  LL223_RS11895 (LL223_2276) comGB 2296130..2297203 (-) 1074 WP_010906319.1 competence type IV pilus assembly protein ComGB Machinery gene
  LL223_RS11900 (LL223_2277) comGA 2297097..2298035 (-) 939 WP_010906320.1 competence type IV pilus ATPase ComGA Machinery gene
  LL223_RS11905 (LL223_2278) - 2298155..2303071 (-) 4917 WP_205288536.1 PolC-type DNA polymerase III -
  LL223_RS11910 (LL223_2279) - 2303244..2303780 (-) 537 WP_010906322.1 hypothetical protein -
  LL223_RS11915 (LL223_2280) - 2303786..2305117 (-) 1332 WP_010906323.1 FAD/NAD(P)-binding oxidoreductase -
  LL223_RS11920 (LL223_2281) - 2305133..2306983 (-) 1851 WP_010906324.1 proline--tRNA ligase -
  LL223_RS11925 (LL223_2282) eeP 2307053..2308339 (-) 1287 WP_010906325.1 RIP metalloprotease RseP Regulator
  LL223_RS11930 (LL223_2283) - 2308358..2309161 (-) 804 WP_003130590.1 phosphatidate cytidylyltransferase -
  LL223_RS11935 (LL223_2284) - 2309161..2309895 (-) 735 WP_010906326.1 isoprenyl transferase -
  LL223_RS11940 (LL223_2285) yajC 2310267..2310599 (-) 333 WP_003130588.1 preprotein translocase subunit YajC -
  LL223_RS11945 (LL223_2286) - 2310694..2311391 (-) 698 Protein_2328 DNA alkylation repair protein -
  LL223_RS11950 (LL223_2287) rlmH 2311410..2311889 (-) 480 WP_003130585.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  LL223_RS11955 (LL223_2288) - 2311928..2312875 (-) 948 WP_003130410.1 IS30 family transposase -
  LL223_RS11960 (LL223_2289) htrA 2313345..2314571 (+) 1227 WP_010906329.1 S1C family serine protease Regulator
  LL223_RS11965 (LL223_2290) - 2314697..2315695 (+) 999 WP_010906330.1 glycosyltransferase family 4 protein -
  LL223_RS11970 (LL223_2291) - 2315821..2317161 (+) 1341 WP_010906331.1 glycosyltransferase family 4 protein -
  LL223_RS11975 (LL223_2292) - 2317269..2317493 (+) 225 WP_003130579.1 YkuJ family protein -
  LL223_RS11980 (LL223_2293) - 2317635..2318639 (+) 1005 WP_010906332.1 hypothetical protein -
  LL223_RS11985 (LL223_2294) - 2318680..2319432 (-) 753 WP_010906333.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  LL223_RS11990 (LL223_2295) polA 2319779..2322412 (-) 2634 WP_010906334.1 DNA polymerase I -
  LL223_RS11995 (LL223_2296) - 2322650..2323459 (+) 810 WP_010906335.1 Cof-type HAD-IIB family hydrolase -
  LL223_RS12000 (LL223_2297) - 2323459..2323866 (+) 408 Protein_2339 LacI family DNA-binding transcriptional regulator -

Sequence


Protein


Download         Length: 94 a.a.        Molecular weight: 10783.02 Da        Isoelectric Point: 5.0604

>NTDB_id=312773 LL223_RS11630 WP_010906314.1 2259687..2259971(-) (comGG) [Lactococcus lactis subsp. lactis strain 223]
MFSMFLQFYLERQIDDARQLRSEKEQLTAELMVSVALKTDLKSQGQIHFDSGDLSYNLLTDSSASSKITDHSSDEKTYQF
SIHLKDGANFQIKN

Nucleotide


Download         Length: 285 bp        

>NTDB_id=312773 LL223_RS11630 WP_010906314.1 2259687..2259971(-) (comGG) [Lactococcus lactis subsp. lactis strain 223]
ATGTTTTCAATGTTTCTTCAGTTCTATTTGGAAAGGCAAATAGATGATGCTCGACAATTAAGAAGTGAAAAGGAGCAGTT
AACAGCTGAATTAATGGTGTCAGTAGCTTTAAAGACTGATTTAAAATCTCAAGGTCAAATTCATTTTGATTCAGGAGATT
TGTCCTACAATTTACTGACAGATTCGTCAGCCAGTTCAAAAATTACTGACCATTCAAGTGATGAAAAAACTTATCAATTT
AGTATCCATCTAAAAGATGGCGCAAACTTTCAAATAAAAAATTAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGG Lactococcus lactis subsp. cremoris KW2

59.14

98.936

0.585


Multiple sequence alignment