Detailed information    

insolico Bioinformatically predicted

Overview

Name   sxy/tfoX   Type   Regulator
Locus tag   CCU01_RS18935 Genome accession   NZ_CP031919
Coordinates   3597017..3597646 (-) Length   209 a.a.
NCBI ID   WP_000839153.1    Uniprot ID   A0A9Q6Y251
Organism   Escherichia coli O145:NM strain FWSEC0002     
Function   positive regulator of competence gene (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3579708..3608834 3597017..3597646 within 0


Gene organization within MGE regions


Location: 3579708..3608834
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCU01_RS18845 (CCU01_019665) dicB 3581433..3581621 (+) 189 WP_000413705.1 cell division inhibition protein DicB -
  CCU01_RS18850 (CCU01_019670) - 3581618..3581809 (+) 192 WP_001098307.1 DUF1482 family protein -
  CCU01_RS18855 (CCU01_019675) - 3581903..3583831 (+) 1929 Protein_3622 exonuclease -
  CCU01_RS18865 (CCU01_019685) - 3585142..3585651 (+) 510 Protein_3624 3'-5' exonuclease -
  CCU01_RS18870 (CCU01_019690) - 3585719..3585961 (+) 243 WP_000273151.1 DUF4224 domain-containing protein -
  CCU01_RS18875 (CCU01_019695) - 3585939..3586958 (+) 1020 WP_001299351.1 tyrosine-type recombinase/integrase -
  CCU01_RS18880 (CCU01_019700) yccA 3587366..3588025 (+) 660 WP_000375136.1 FtsH protease modulator YccA -
  CCU01_RS18885 (CCU01_019705) tusE 3588116..3588445 (+) 330 WP_000904442.1 sulfurtransferase TusE -
  CCU01_RS18890 (CCU01_019710) yccX 3588442..3588720 (-) 279 WP_000048228.1 acylphosphatase -
  CCU01_RS18895 (CCU01_019715) rlmI 3588815..3590005 (+) 1191 WP_000116291.1 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI -
  CCU01_RS18900 (CCU01_019720) hspQ 3590063..3590380 (+) 318 WP_001295356.1 heat shock protein HspQ -
  CCU01_RS18905 (CCU01_019725) yccU 3590425..3590838 (-) 414 WP_000665217.1 CoA-binding protein -
  CCU01_RS18910 (CCU01_019730) yccT 3591011..3591673 (+) 663 WP_000847791.1 DUF2057 family protein -
  CCU01_RS18915 (CCU01_019735) mgsA 3591769..3592227 (+) 459 WP_000424181.1 methylglyoxal synthase -
  CCU01_RS18920 (CCU01_019740) helD 3592259..3594313 (-) 2055 WP_044869326.1 DNA helicase IV -
  CCU01_RS18925 (CCU01_019745) yccF 3594436..3594882 (+) 447 WP_001261235.1 YccF domain-containing protein -
  CCU01_RS18930 (CCU01_019750) yccS 3594892..3597054 (+) 2163 WP_000875041.1 YccS family putative transporter -
  CCU01_RS18935 (CCU01_019755) sxy/tfoX 3597017..3597646 (-) 630 WP_000839153.1 CRP-S regulon transcriptional coactivator Sxy Regulator
  CCU01_RS18940 (CCU01_019760) sulA 3597865..3598374 (+) 510 WP_000288710.1 SOS-induced cell division inhibitor SulA -
  CCU01_RS18945 (CCU01_019770) ompA 3598731..3599786 (+) 1056 WP_000750414.1 porin OmpA -
  CCU01_RS18950 (CCU01_019775) matP 3599861..3600313 (-) 453 WP_000877161.1 macrodomain Ter protein MatP -
  CCU01_RS18955 (CCU01_019780) ycbZ 3600499..3602259 (+) 1761 WP_000156509.1 Lon protease family protein -
  CCU01_RS18960 (CCU01_019785) fabA 3602328..3602846 (+) 519 WP_000227927.1 bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase -
  CCU01_RS18965 (CCU01_019790) rmf 3602916..3603083 (-) 168 WP_000828648.1 ribosome modulation factor -
  CCU01_RS18970 (CCU01_019795) pqiC 3603339..3603902 (-) 564 WP_000759123.1 membrane integrity-associated transporter subunit PqiC -
  CCU01_RS18975 (CCU01_019800) pqiB 3603899..3605539 (-) 1641 WP_000445542.1 intermembrane transport protein PqiB -
  CCU01_RS18980 (CCU01_019805) pqiA 3605544..3606797 (-) 1254 WP_000333170.1 membrane integrity-associated transporter subunit PqiA -
  CCU01_RS18985 (CCU01_019810) uup 3606927..3608834 (-) 1908 WP_000053100.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 24147.02 Da        Isoelectric Point: 9.2180

>NTDB_id=312706 CCU01_RS18935 WP_000839153.1 3597017..3597646(-) (sxy/tfoX) [Escherichia coli O145:NM strain FWSEC0002]
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=312706 CCU01_RS18935 WP_000839153.1 3597017..3597646(-) (sxy/tfoX) [Escherichia coli O145:NM strain FWSEC0002]
ATGAAAAGCCTCTCCTATAAGCGGATCTATAAATCACAAGAATACCTGGCAACGTTGGGCACAATTGAATACCGATCATT
GTTTGGTAGTTACAGCCTGACCGTTGACGACACGGTGTTTGCGATGGTTTCTGATGGTGAGTTGTATCTTCGGGCTTGTG
AGCAAAGTGCACAGTACTGTGTAAAACATCCGCCTGTCTGGCTGACATATAAAAAGTGTGGCCGATCCGTTACCCTCAAT
TACTATCGGGTTGATGAAAGTCTATGGCGAAATCAACTGAAGCTGGTGCGTCTGTCGAAATATTCTCTCGATGCAGCGCT
GAAAGAGAAAAGCACGCGCAATACCCGGGAAAGACTGAAAGATTTGCCCAATATGTCTTTTCATCTGGAAGCGATTCTCG
GGGAGGTGGGGATTAAGGATGTACGGGCGTTACGTATACTTGGGGCAAAAATGTGTTGGTTGCGACTGCGGCAGCAAAAC
AGTCTGGTGACAGAAAAGATTCTGTTTATGCTTGAAGGTGCCATTATCGGCATTCATGAAGCTGCGCTCCCGGTGGCACG
CCGCCAGGAGCTTGCAGAATGGGCTGACTCTCTTACGCCGAAACAGGAGTTTCCTGCGGAACTTGAGTAA

Domains

Predicted by InterproScan.

TfoX N-terminal domain (TfoX_N)

(14-106)

TfoX C-terminal domain (TfoX_C)

(116-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sxy/tfoX Escherichia coli BW25113 strain K-12

100

100

1

Multiple sequence alignment