Detailed information NTG0312473

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: D1E86_RS14270
• Genome accession: NZ_CP031888
• Coordinates: 2764343..2765230 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CFSAN082782
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2759343..2770230

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1E86_RS14235 (D1E86_14575)	-	2759362..2759454 (+)	93	WP_010956583.1	hypothetical protein	-
D1E86_RS14240 (D1E86_14580)	-	2759562..2760059 (-)	498	WP_001065268.1	glutathione peroxidase	-
D1E86_RS14245 (D1E86_14585)	-	2760069..2760329 (-)	261	WP_001789910.1	hypothetical protein	-
D1E86_RS14255 (D1E86_14595)	-	2760711..2760824 (-)	114	WP_001791776.1	hypothetical protein	-
D1E86_RS14260 (D1E86_14600)	-	2761483..2763483 (-)	2001	WP_000776751.1	ABC transporter permease	-
D1E86_RS14265 (D1E86_14605)	-	2763480..2764235 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
D1E86_RS14270 (D1E86_14610)	braS	2764343..2765230 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
D1E86_RS14275 (D1E86_14615)	braR	2765241..2765906 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
D1E86_RS14280 (D1E86_14620)	-	2765932..2766132 (-)	201	WP_149557721.1	hypothetical protein	-
D1E86_RS14285 (D1E86_14625)	-	2766330..2767754 (+)	1425	WP_000953744.1	alkaline phosphatase	-
D1E86_RS15170 (D1E86_14630)	-	2767814..2767915 (-)	102	WP_000731972.1	SE2200 family small protein	-
D1E86_RS14295 (D1E86_14635)	-	2768037..2768492 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
D1E86_RS14300 (D1E86_14640)	-	2768737..2769498 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=312473 D1E86_RS14270 WP_000143419.1 2764343..2765230(-) (braS) [Staphylococcus aureus strain CFSAN082782]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=312473 D1E86_RS14270 WP_000143419.1 2764343..2765230(-) (braS) [Staphylococcus aureus strain CFSAN082782]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997