Detailed information NTG0312307

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: D1O36_RS00560
• Genome accession: NZ_CP031881
• Coordinates: 88883..91333 (+)
• Length: 816 a.a.
• NCBI ID: WP_134973023.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST106
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 83883..96333

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1O36_RS00530 (D1O36_00530)	-	84209..85207 (-)	999	WP_134973022.1	S66 peptidase family protein	-
D1O36_RS00540 (D1O36_00540)	rpsB	85685..86452 (+)	768	WP_082308795.1	30S ribosomal protein S2	-
D1O36_RS00545 (D1O36_00545)	tsf	86563..87603 (+)	1041	WP_014621027.1	translation elongation factor Ts	-
D1O36_RS00550 (D1O36_00550)	-	87713..88183 (-)	471	WP_011680613.1	small multi-drug export protein	-
D1O36_RS00555 (D1O36_00555)	-	88427..88882 (+)	456	WP_002949111.1	CtsR family transcriptional regulator	-
D1O36_RS00560 (D1O36_00560)	clpC	88883..91333 (+)	2451	WP_134973023.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
D1O36_RS10950 (D1O36_00565)	pbp3	91461..92718 (-)	1258	Protein_74	D-alanyl-D-alanine carboxypeptidase PBP3	-
D1O36_RS00570 (D1O36_00570)	-	92917..94487 (+)	1571	WP_087009847.1	IS3-like element ISSth1b family transposase	-
D1O36_RS00575 (D1O36_00575)	pbp3	94550..95797 (-)	1248	WP_209019386.1	D-alanyl-D-alanine carboxypeptidase PBP3	-

Sequence

Protein

• Length: 816 a.a.
• Molecular weight: 90467.66 Da
• Isoelectric Point: 5.7962

>NTDB_id=312307 D1O36_RS00560 WP_134973023.1 88883..91333(+) (clpC) [Streptococcus thermophilus strain ST106]
MTIYSRKMQAIFHRAQLEAERFESPFLETWHVLLAMVEVTGSVAYLTFTDFEDRIHSEEIETAAVLAMEKRPKDLSESDI
IDLRAQSPALEAMLQEAQEIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERNAGLS
KQDLKAIHDLRKPKKSKASANFANMMQPPQSSTGELADYTKDLTALAESGNLDPVIGRDEEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKYAALSRRFAKITIEEPSVSEAIDILNGLRSSYEDYHRVTI
TDAAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQVRIKKEDKREITPLDEALISGDIGAAVKQYKANQKAKFPKPAL
VDADQIMQTLSRLSGIPVEKMTQTDSKRYLNLESELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEIEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAQTISHNHQAMQARIMEELKKSYRPEFINRIDEKVV
FHSLEEEQLHDIVKIMVKPLISALSDKGISLKFQPAALKHLAKNGYDIEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide

• Length: 2451 bp

>NTDB_id=312307 D1O36_RS00560 WP_134973023.1 88883..91333(+) (clpC) [Streptococcus thermophilus strain ST106]
ATGACGATATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAAGCGGAGCGTTTTGAAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTAACGGGATCTGTAGCCTACTTAACATTTACTGATTTTGAGGACC
GTATTCATTCGGAAGAGATTGAGACAGCTGCTGTATTGGCTATGGAGAAGAGGCCAAAAGACTTATCGGAATCAGATATT
ATCGATTTACGTGCACAGTCACCTGCGCTAGAGGCTATGTTGCAAGAGGCGCAAGAAATCGCTAGTGTTACTGGTGCTGT
AGAGGTGGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTAATGGTTTGTCGCCTCCTTGAAGTGGCTG
GTTTTCAATATAAAGATGATAGCGATAAACCTCGCATCATAGATTTACGACGTTCTTTGGAGCGTAATGCTGGTCTTAGC
AAGCAAGATTTGAAGGCAATTCACGATCTTCGTAAACCTAAGAAATCAAAAGCATCTGCGAATTTTGCCAATATGATGCA
ACCTCCTCAATCATCTACTGGTGAACTGGCAGATTATACCAAAGACTTAACTGCATTAGCGGAGTCAGGAAATCTTGATC
CCGTTATTGGACGCGATGAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAATCCTGTCTTGGTA
GGTGAAGCTGGTGTCGGTAAGACAGCACTTGCTCTTGGTTTAGCGCAACGTATTGCTTCAGGCGAAGTACCATTTGAATT
GGCTGATATGCGTATCTTAGAGCTTGACATGATGAGCGTTGTTGCAGGGACACGTTTCCGTGGTGATTTCGAAGAGCGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGGAAAATCATTCTCTTTATTGACGAACTACATACGATTATTGGATCT
GGTTCAGGTATTGATAGTACCTTGGATGCGGCTAATATTTTGAAACCGGCCCTTGCGCGCGGGACACTTCACATGGTTGG
AGCAACCACGCAAGCTGAATACCAAAAGCATATTGAGAAATATGCAGCTTTATCCCGTCGTTTTGCTAAAATTACAATTG
AAGAACCAAGTGTATCTGAAGCAATCGATATTTTAAACGGTTTACGTTCGTCTTATGAAGACTATCATCGTGTGACTATT
ACGGACGCGGCAGTTGAGACGGCAGTCAAGGCAGCGCATCGCTATTTGACGAGTAAGAATTTGCCTGATTCGGCAATTGA
CCTTTTAGATGAAGCGAGTGCAACTGTTCAAGTTCGTATCAAAAAAGAGGACAAACGTGAGATAACGCCTTTGGATGAAG
CACTTATATCTGGGGATATTGGGGCTGCTGTTAAACAGTATAAGGCTAACCAAAAGGCAAAATTTCCTAAACCTGCTTTG
GTAGATGCGGATCAGATTATGCAAACTCTTAGTCGTTTATCAGGTATCCCTGTTGAGAAGATGACGCAGACTGACAGCAA
GCGTTACCTGAATCTTGAATCAGAACTCCACAAACGTGTTATTGGTCAAGATGAGGCGGTTTCGGCTATCAGCCGTGCTA
TTCGTCGTAATCAGTCAGGTATTCGTACTGGAAAACGTCCTATTGGCTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAATTGGCTAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAATCAGCTTTGCTTCGCTTTGATATGTCGGAGTA
TATGGAAAAATTTGCGGCTAGTCGCCTTAATGGTGCTCCTCCAGGGTATGTCGGATATGATGAGGGTGGAGAGTTGACAG
AGAAAGTTCGAAATAAGCCCTACTCAGTTCTTCTCTTTGACGAGATTGAGAAAGCTCATCCTGATATCTTCAACATTCTC
TTACAGGTTTTGGATGACGGTGTTTTAACAGATAGCCGTGGTCGTAAGGTTGATTTTTCAAACACTATCATCATTATGAC
CTCAAATTTGGGAGCTACAGCTCTTCGTGATGATAAAACTGTTGGTTTTGGTGCTCAAACTATTTCTCATAATCACCAAG
CCATGCAAGCACGCATTATGGAAGAGCTTAAGAAGTCCTATCGTCCAGAATTTATTAACCGTATTGATGAGAAGGTTGTC
TTCCACAGCTTAGAGGAAGAACAACTACATGACATTGTCAAGATTATGGTTAAACCATTAATTTCGGCTCTATCCGATAA
AGGTATAAGCTTAAAATTCCAACCAGCTGCTCTTAAGCATTTGGCTAAGAATGGCTATGATATTGAGATGGGAGCTCGTC
CATTACGTCGTACGATTCAAACTCAAGTGGAGGACAAGTTGTCTGAGTTATTACTAGGTGGCCAAGTTGTTAGCGGACAG
ACCCTTAAGATTGGTTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-135)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-45)

• AAA domain (Cdc48 subfamily) (AAA_2) (546-717)

• AAA lid domain (AAA_lid_9) (377-454)

• ATPase family associated with various cellular activities (AAA) (AAA) (238-368)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (724-804)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus thermophilus LMD-9	99.632	100	0.996
clpC	Streptococcus thermophilus LMG 18311	99.02	100	0.99
clpC	Streptococcus mutans UA159	72.304	100	0.723
clpC	Streptococcus pneumoniae TIGR4	65.971	99.755	0.658
clpC	Streptococcus pneumoniae Rx1	65.848	99.755	0.657
clpC	Streptococcus pneumoniae D39	65.848	99.755	0.657
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.301	100	0.512
clpC	Bacillus subtilis subsp. subtilis str. 168	46.529	100	0.468
clpE	Streptococcus mutans UA159	47.444	76.716	0.364