Detailed information NTG0312166

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: D1102_RS08945
• Genome accession: NZ_CP031865
• Coordinates: 1883976..1884632 (+)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae serovar 9 str. CVJ13261
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 1878976..1889632

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1102_RS08900 (D1102_08925)	rplP	1879047..1879457 (-)	411	WP_005599294.1	50S ribosomal protein L16	-
D1102_RS08905 (D1102_08930)	rpsC	1879471..1880178 (-)	708	WP_005599293.1	30S ribosomal protein S3	-
D1102_RS08910 (D1102_08935)	rplV	1880197..1880529 (-)	333	WP_005599292.1	50S ribosomal protein L22	-
D1102_RS08915 (D1102_08940)	rpsS	1880540..1880815 (-)	276	WP_005539416.1	30S ribosomal protein S19	-
D1102_RS08920 (D1102_08945)	rplB	1880843..1881664 (-)	822	WP_005599291.1	50S ribosomal protein L2	-
D1102_RS08925 (D1102_08950)	rplW	1881685..1881990 (-)	306	WP_005599290.1	50S ribosomal protein L23	-
D1102_RS08930 (D1102_08955)	rplD	1881987..1882589 (-)	603	WP_005599282.1	50S ribosomal protein L4	-
D1102_RS08935 (D1102_08960)	rplC	1882605..1883231 (-)	627	WP_005599280.1	50S ribosomal protein L3	-
D1102_RS08940 (D1102_08965)	rpsJ	1883257..1883568 (-)	312	WP_001181005.1	30S ribosomal protein S10	-
D1102_RS08945 (D1102_08970)	sxy/tfoX	1883976..1884632 (+)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
D1102_RS08950 (D1102_08975)	fumC	1884787..1886181 (+)	1395	WP_005599273.1	class II fumarate hydratase	-
D1102_RS08955 (D1102_08980)	nagA	1886330..1887475 (-)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
D1102_RS08960 (D1102_08985)	nagB	1887527..1888330 (-)	804	WP_005610807.1	glucosamine-6-phosphate deaminase	-
D1102_RS08965 (D1102_08990)	nanA	1888380..1889258 (-)	879	WP_005599265.1	N-acetylneuraminate lyase	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=312166 D1102_RS08945 WP_005609196.1 1883976..1884632(+) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 9 str. CVJ13261]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=312166 D1102_RS08945 WP_005609196.1 1883976..1884632(+) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 9 str. CVJ13261]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376