Detailed information NTG0311679

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: D1G35_RS04450
• Genome accession: NZ_CP031838
• Coordinates: 850906..851949 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain QD-CD9
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 845906..856949

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1G35_RS04415 (D1G35_04415)	-	846451..846561 (+)	111	WP_031775032.1	hypothetical protein	-
D1G35_RS04420 (D1G35_04420)	-	846590..847003 (+)	414	WP_001670387.1	hypothetical protein	-
D1G35_RS04430 (D1G35_04430)	-	847434..848420 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
D1G35_RS04435 (D1G35_04435)	map	848832..849590 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
D1G35_RS04440 (D1G35_04440)	-	849807..850193 (+)	387	WP_001110179.1	hypothetical protein	-
D1G35_RS04445 (D1G35_04445)	liaF	850208..850909 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
D1G35_RS04450 (D1G35_04450)	vraS	850906..851949 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
D1G35_RS04455 (D1G35_04455)	vraR	851939..852568 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
D1G35_RS04460 (D1G35_04460)	-	852680..853897 (-)	1218	WP_000037078.1	YihY/virulence factor BrkB family protein	-
D1G35_RS04465 (D1G35_04465)	-	854175..854450 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
D1G35_RS04470 (D1G35_04470)	-	854457..854921 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
D1G35_RS04475 (D1G35_04475)	-	855068..855268 (+)	201	WP_000180460.1	DUF1128 family protein	-
D1G35_RS04480 (D1G35_04480)	-	855271..856527 (+)	1257	WP_001789555.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=311679 D1G35_RS04450 WP_001017131.1 850906..851949(+) (vraS) [Staphylococcus aureus strain QD-CD9]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=311679 D1G35_RS04450 WP_001017131.1 850906..851949(+) (vraS) [Staphylococcus aureus strain QD-CD9]
ATGAACCACTATATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1