Detailed information NTG0311198

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: D1F65_RS13835
• Genome accession: NZ_CP031779
• Coordinates: 2680434..2681321 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CFBR-105
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2675434..2686321

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D1F65_RS13800 (D1F65_13800)	-	2675453..2675545 (+)	93	WP_010956583.1	hypothetical protein	-
D1F65_RS13805 (D1F65_13805)	-	2675653..2676150 (-)	498	WP_001065268.1	glutathione peroxidase	-
D1F65_RS13810 (D1F65_13810)	-	2676160..2676420 (-)	261	WP_001791974.1	hypothetical protein	-
D1F65_RS13820 (D1F65_13820)	-	2676802..2676915 (-)	114	Protein_2567	hypothetical protein	-
D1F65_RS13825 (D1F65_13825)	-	2677574..2679574 (-)	2001	WP_000776750.1	ABC transporter permease	-
D1F65_RS13830 (D1F65_13830)	-	2679571..2680326 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
D1F65_RS13835 (D1F65_13835)	braS	2680434..2681321 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
D1F65_RS13840 (D1F65_13840)	braR	2681332..2681997 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
D1F65_RS13845 (D1F65_13845)	-	2682023..2682223 (-)	201	WP_000604730.1	hypothetical protein	-
D1F65_RS13850 (D1F65_13850)	-	2682421..2683845 (+)	1425	WP_000953755.1	alkaline phosphatase	-
D1F65_RS14560 (D1F65_13855)	-	2683905..2684006 (-)	102	WP_000731976.1	SE2200 family small protein	-
D1F65_RS13860 (D1F65_13860)	-	2684128..2684583 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
D1F65_RS13865 (D1F65_13865)	-	2684828..2685589 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=311198 D1F65_RS13835 WP_000143425.1 2680434..2681321(-) (braS) [Staphylococcus aureus strain CFBR-105]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=311198 D1F65_RS13835 WP_000143425.1 2680434..2681321(-) (braS) [Staphylococcus aureus strain CFBR-105]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1