Detailed information NTG0310882

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: D0Z58_RS01460
• Genome accession: NZ_CP031738
• Coordinates: 268499..269569 (+)
• Length: 356 a.a.
• NCBI ID: WP_002986002.1
• Uniprot ID: Q1JNF7
• Organism: Streptococcus pyogenes strain SP1336
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 263499..274569

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D0Z58_RS01445 (D0Z58_01450)	amiA	264027..265997 (+)	1971	WP_024623426.1	peptide ABC transporter substrate-binding protein	Regulator
D0Z58_RS01450 (D0Z58_01455)	amiC	266062..267564 (+)	1503	WP_002991105.1	ABC transporter permease	Regulator
D0Z58_RS01455 (D0Z58_01460)	amiD	267564..268490 (+)	927	WP_002986004.1	oligopeptide ABC transporter permease OppC	Regulator
D0Z58_RS01460 (D0Z58_01465)	amiE	268499..269569 (+)	1071	WP_002986002.1	ABC transporter ATP-binding protein	Regulator
D0Z58_RS01465 (D0Z58_01470)	amiF	269562..270485 (+)	924	WP_002986000.1	ABC transporter ATP-binding protein	Regulator
D0Z58_RS01470 (D0Z58_01475)	-	270634..270873 (-)	240	WP_002991102.1	hypothetical protein	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39749.85 Da
• Isoelectric Point: 5.7015

>NTDB_id=310882 D0Z58_RS01460 WP_002986002.1 268499..269569(+) (amiE) [Streptococcus pyogenes strain SP1336]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGRQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=310882 D0Z58_RS01460 WP_002986002.1 268499..269569(+) (amiE) [Streptococcus pyogenes strain SP1336]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGACAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTAATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: Q1JNF7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.389	100	0.772
amiE	Streptococcus thermophilus LMG 18311	75.278	100	0.761
amiE	Streptococcus thermophilus LMD-9	75.278	100	0.761
oppD	Streptococcus mutans UA159	56.677	94.663	0.537