Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DDV21_RS09090 Genome accession   NZ_CP031733
Coordinates   1900212..1901510 (-) Length   432 a.a.
NCBI ID   WP_116878862.1    Uniprot ID   A0A372KJK8
Organism   Streptococcus chenjunshii strain Z15     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1895212..1906510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DDV21_RS09080 (DDV21_009080) raiA 1898928..1899476 (-) 549 WP_116878860.1 ribosome-associated translation inhibitor RaiA -
  DDV21_RS09085 (DDV21_009085) comFC/cflB 1899550..1900212 (-) 663 WP_116878861.1 ComF family protein Machinery gene
  DDV21_RS09090 (DDV21_009090) comFA/cflA 1900212..1901510 (-) 1299 WP_116878862.1 DEAD/DEAH box helicase Machinery gene
  DDV21_RS09095 (DDV21_009095) - 1901568..1902194 (+) 627 WP_116878863.1 YigZ family protein -
  DDV21_RS09100 (DDV21_009100) cysK 1902322..1903251 (+) 930 WP_116878864.1 cysteine synthase A -
  DDV21_RS09105 (DDV21_009105) - 1903312..1903674 (-) 363 WP_116878865.1 S1 RNA-binding domain-containing protein -
  DDV21_RS09110 (DDV21_009110) - 1903674..1905074 (-) 1401 WP_116878866.1 Cof-type HAD-IIB family hydrolase -
  DDV21_RS09115 (DDV21_009115) - 1905115..1905756 (-) 642 WP_116878867.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49127.44 Da        Isoelectric Point: 10.2164

>NTDB_id=310853 DDV21_RS09090 WP_116878862.1 1900212..1901510(-) (comFA/cflA) [Streptococcus chenjunshii strain Z15]
MDCLDDYFGRLFTEIQLPAEIRKQAQTCPAAIKKGNSWFCVRCSSLISRENALPNGEYYCRNCLVFGRISTKASLYFFRQ
QKFPAVRSLIWTGKLTTYQKRVSDALVSNLEKGDHLLVHAVTGAGKTEMIYKMVASVIDQGKAVCIASPRVDVCIELYKR
LTSAFSCPITLLHGNSDPYKRAPLLIATTHQLLKFYRAFDLLIIDEVDAFPFTDNNMLYHGTEKSLKKDGIKIFLTATST
ERLDRQVKKGQLKKLHLARRFHGKPLVIPKTQWLGNLLTEMDRGRLPRKLLTMIEKQRKTGFPLLLFFPNIEKGERLAVI
LQRYFTADSIACVSSQSENRLELIEQFRKGNLQILVSTTILERGVTFPNLDVFILLAHHHLYTKSSLIQMAGRVGRSSDR
PTGELIFFHNGLTKSIKKAISEIKEMNQKGGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=310853 DDV21_RS09090 WP_116878862.1 1900212..1901510(-) (comFA/cflA) [Streptococcus chenjunshii strain Z15]
ATGGATTGTTTAGATGATTACTTCGGCCGTTTATTTACTGAGATACAGCTGCCAGCTGAAATAAGAAAACAAGCTCAAAC
CTGTCCTGCAGCAATAAAAAAAGGCAATTCTTGGTTTTGTGTCCGCTGCTCGTCCTTGATTTCTCGGGAGAATGCTCTGC
CAAACGGAGAGTATTACTGTAGAAATTGTTTGGTATTCGGCAGGATTTCTACCAAAGCTTCCTTATATTTTTTTCGGCAG
CAAAAATTTCCTGCTGTTCGTTCGTTAATTTGGACAGGAAAGCTGACCACCTATCAAAAAAGAGTATCAGATGCTTTGGT
GTCAAATCTTGAAAAAGGAGACCATTTGCTGGTTCATGCAGTTACGGGAGCTGGGAAAACGGAGATGATTTATAAAATGG
TCGCCAGTGTTATTGATCAGGGAAAAGCTGTCTGTATAGCCAGTCCCAGAGTAGATGTTTGCATAGAACTTTATAAACGC
CTGACTTCTGCTTTTTCCTGTCCTATTACTCTCCTGCATGGAAACTCCGATCCTTATAAACGTGCCCCTTTGCTTATTGC
GACAACGCACCAATTGTTAAAATTTTATCGGGCTTTTGATTTGCTGATTATAGATGAAGTGGATGCTTTCCCATTTACAG
ATAATAATATGCTTTATCATGGAACAGAAAAAAGTCTGAAAAAAGATGGCATTAAGATTTTTTTAACAGCCACCTCCACT
GAGAGGTTAGACAGACAAGTGAAAAAAGGACAGCTAAAAAAGCTGCATCTTGCTCGGCGCTTTCATGGAAAACCGTTAGT
TATCCCTAAAACACAGTGGCTGGGAAATCTTTTAACAGAGATGGACAGAGGCCGGCTTCCCAGAAAATTGCTCACGATGA
TAGAAAAACAAAGAAAAACCGGCTTCCCTCTCCTTTTATTTTTTCCAAATATAGAGAAAGGTGAGAGGCTGGCTGTCATT
TTACAGCGCTATTTCACCGCTGACTCGATTGCCTGCGTCTCCAGTCAGTCAGAAAATCGGCTGGAATTAATAGAGCAGTT
TCGCAAAGGCAATCTTCAGATATTGGTGTCAACAACTATTTTAGAACGTGGGGTAACATTTCCTAATCTTGATGTTTTTA
TCTTACTGGCTCATCATCATTTATACACTAAAAGCAGCTTAATTCAGATGGCCGGCCGTGTCGGCCGATCGTCGGACAGA
CCGACCGGAGAATTAATTTTCTTTCATAATGGCTTAACAAAATCAATAAAAAAAGCTATTTCAGAAATTAAGGAAATGAA
TCAAAAAGGAGGCTTCTAG

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(288-397)

Type III restriction enzyme, res subunit (ResIII)

(94-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A372KJK8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

58.782

98.843

0.581
  comFA/cflA Streptococcus pneumoniae D39

58.782

98.843

0.581
  comFA/cflA Streptococcus pneumoniae R6

58.782

98.843

0.581
  comFA/cflA Streptococcus pneumoniae TIGR4

58.782

98.843

0.581
  comFA/cflA Streptococcus mitis NCTC 12261

58.314

98.843

0.576
  comFA/cflA Streptococcus mitis SK321

57.377

98.843

0.567
  comFA Lactococcus lactis subsp. cremoris KW2

48.622

92.361

0.449
  comFA Latilactobacillus sakei subsp. sakei 23K

37.269

100

0.373

Multiple sequence alignment