Detailed information
Bioinformatically predicted
Overview
| Name | pilA | Type | Machinery gene |
| Locus tag | APP7_RS04775 | Genome accession | NC_010939 |
| Coordinates | 1053857..1054303 (-) | Length | 148 a.a. |
| NCBI ID | WP_005597397.1 | Uniprot ID | B0BPG5 |
| Organism | Actinobacillus pleuropneumoniae serovar 7 str. AP76 | ||
| Function | type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake |
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Genomic Context
Location: 1048857..1059303
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| APP7_RS04750 (APP7_0934) | yacG | 1049764..1049952 (-) | 189 | WP_005597388.1 | DNA gyrase inhibitor YacG | - |
| APP7_RS04755 (APP7_0935) | coaE | 1049934..1050572 (-) | 639 | WP_005617375.1 | dephospho-CoA kinase | - |
| APP7_RS04760 (APP7_0936) | - | 1050594..1051232 (-) | 639 | WP_012478451.1 | prepilin peptidase | - |
| APP7_RS04765 (APP7_0937) | pilC | 1051259..1052461 (-) | 1203 | WP_005617379.1 | type II secretion system F family protein | Machinery gene |
| APP7_RS04770 (APP7_0938) | pilB | 1052445..1053839 (-) | 1395 | WP_005601209.1 | GspE/PulE family protein | Machinery gene |
| APP7_RS04775 (APP7_0939) | pilA | 1053857..1054303 (-) | 447 | WP_005597397.1 | prepilin-type N-terminal cleavage/methylation domain-containing protein | Machinery gene |
| APP7_RS04780 (APP7_0940) | radA | 1054485..1055864 (+) | 1380 | WP_017357656.1 | DNA repair protein RadA | - |
| APP7_RS04785 (APP7_0941) | - | 1055908..1056141 (-) | 234 | WP_005615190.1 | YgjV family protein | - |
| APP7_RS04790 (APP7_0942) | folA | 1056268..1056756 (-) | 489 | WP_005597400.1 | type 3 dihydrofolate reductase | - |
| APP7_RS04795 (APP7_0943) | proB | 1056843..1057934 (+) | 1092 | WP_005601213.1 | glutamate 5-kinase | - |
| APP7_RS04800 (APP7_0944) | - | 1057947..1058723 (+) | 777 | WP_005597402.1 | TSUP family transporter | - |
Sequence
Protein
Download Length: 148 a.a. Molecular weight: 15980.38 Da Isoelectric Point: 7.6257
>NTDB_id=31075 APP7_RS04775 WP_005597397.1 1053857..1054303(-) (pilA) [Actinobacillus pleuropneumoniae serovar 7 str. AP76]
MQKLSLIRPLTNAFTLIELMIVIAIIAILATVAIPSYNSYTQKAALSELLAASASYKTDVEICIYNTGDSKNCSGGQNGV
RKMTELRQAKYLNAITVEGGTITVTGKGNLQEYGYTMTPIHNGSTISWETKCKGEDLSLFPANFCASN
MQKLSLIRPLTNAFTLIELMIVIAIIAILATVAIPSYNSYTQKAALSELLAASASYKTDVEICIYNTGDSKNCSGGQNGV
RKMTELRQAKYLNAITVEGGTITVTGKGNLQEYGYTMTPIHNGSTISWETKCKGEDLSLFPANFCASN
Nucleotide
Download Length: 447 bp
>NTDB_id=31075 APP7_RS04775 WP_005597397.1 1053857..1054303(-) (pilA) [Actinobacillus pleuropneumoniae serovar 7 str. AP76]
ATGCAAAAATTAAGTCTTATTCGACCGCTTACTAACGCGTTTACTTTAATTGAATTGATGATCGTGATTGCGATTATTGC
CATTTTAGCTACGGTTGCAATTCCGTCATATAACAGTTATACCCAAAAAGCGGCGCTTTCGGAGCTATTGGCGGCATCGG
CTTCTTATAAAACGGATGTCGAGATCTGCATATATAACACCGGAGATTCTAAAAACTGTAGCGGCGGTCAAAACGGTGTC
AGAAAAATGACGGAGCTTAGACAGGCTAAATATTTAAATGCCATTACGGTGGAAGGCGGAACGATTACAGTAACGGGGAA
AGGGAATCTACAGGAATACGGTTATACGATGACACCGATTCATAACGGTAGCACTATTTCTTGGGAAACGAAATGTAAAG
GGGAGGACTTAAGTTTATTTCCGGCAAATTTCTGCGCATCAAATTAA
ATGCAAAAATTAAGTCTTATTCGACCGCTTACTAACGCGTTTACTTTAATTGAATTGATGATCGTGATTGCGATTATTGC
CATTTTAGCTACGGTTGCAATTCCGTCATATAACAGTTATACCCAAAAAGCGGCGCTTTCGGAGCTATTGGCGGCATCGG
CTTCTTATAAAACGGATGTCGAGATCTGCATATATAACACCGGAGATTCTAAAAACTGTAGCGGCGGTCAAAACGGTGTC
AGAAAAATGACGGAGCTTAGACAGGCTAAATATTTAAATGCCATTACGGTGGAAGGCGGAACGATTACAGTAACGGGGAA
AGGGAATCTACAGGAATACGGTTATACGATGACACCGATTCATAACGGTAGCACTATTTCTTGGGAAACGAAATGTAAAG
GGGAGGACTTAAGTTTATTTCCGGCAAATTTCTGCGCATCAAATTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilA | Glaesserella parasuis strain SC1401 |
68.919 |
100 |
0.689 |
| pilA | Haemophilus influenzae 86-028NP |
55.102 |
99.324 |
0.547 |
| pilA | Haemophilus influenzae Rd KW20 |
53.061 |
99.324 |
0.527 |