Detailed information NTG0310511

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: D0T90_RS04715
• Genome accession: NZ_CP031699
• Coordinates: 1024189..1025421 (+)
• Length: 410 a.a.
• NCBI ID: WP_123796368.1
• Uniprot ID: A0A5P3MWE4
• Organism: Neisseria animalis strain ATCC 49930
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1019189..1030421

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
D0T90_RS04705 (D0T90_04880)	comE	1021972..1022259 (+)	288	WP_126325826.1	helix-hairpin-helix domain-containing protein	Machinery gene
D0T90_RS04710 (D0T90_04885)	-	1022496..1023917 (-)	1422	WP_123796369.1	OmpP1/FadL family transporter	-
D0T90_RS04715 (D0T90_04890)	dprA	1024189..1025421 (+)	1233	WP_123796368.1	DNA-processing protein DprA	Machinery gene
D0T90_RS04720 (D0T90_04895)	-	1025484..1025939 (+)	456	WP_123796367.1	DUF494 family protein	-
D0T90_RS04725 (D0T90_04900)	topA	1026079..1028403 (+)	2325	WP_123796365.1	type I DNA topoisomerase	-
D0T90_RS04730 (D0T90_04905)	-	1028502..1028927 (-)	426	WP_123796364.1	hypothetical protein	-
D0T90_RS04735 (D0T90_04915)	-	1029219..1029863 (-)	645	WP_123796363.1	hypothetical protein	-
D0T90_RS04740 (D0T90_04920)	pyrI	1029892..1030350 (-)	459	WP_123796366.1	aspartate carbamoyltransferase regulatory subunit	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 43801.14 Da
• Isoelectric Point: 6.5888

>NTDB_id=310511 D0T90_RS04715 WP_123796368.1 1024189..1025421(+) (dprA) [Neisseria animalis strain ATCC 49930]
MSETERFAWLQLALTPYIGAETFLKLLQHFGSVEAALAAPSEFVGRAARNKQAAAVWDNREKRELARQSALEALEWETQA
DCRLMLLKDDDFPVMLAEGLTPPPLLFLRGNTALLHSPSVAIVGSRHATPQAVRIARDFGEALGKEGITVVSGMAAGIDA
AAHQGALLADGGGTIAVWGTGINRIYPPSNKQLAYEIAGHGLIVSEFPLGTRPLAGNFPRRNRLIAALSCATLVVEAALE
SGSLITTKLAAEMGREVMAVPGSIDNPHSKGCHKLIKEGAKLVECLDDIVQECPQLLQNASISSYSINKQRKKAERPSAN
TLSAAKNEKLPLAEPEKNQTEAVRPSEKIQAAQSAQADSILAAMGYDPVHPDMLAAQTGLAAADIYAKLLEHELEGTVAA
LAGGRYQRIR

Nucleotide

• Length: 1233 bp

>NTDB_id=310511 D0T90_RS04715 WP_123796368.1 1024189..1025421(+) (dprA) [Neisseria animalis strain ATCC 49930]
ATTAGTGAAACAGAACGCTTTGCTTGGCTACAGTTGGCGTTGACACCTTATATTGGTGCGGAAACCTTTCTCAAATTGCT
GCAACATTTCGGCAGTGTGGAAGCGGCATTGGCCGCACCGTCAGAGTTTGTTGGGCGGGCAGCCCGTAATAAGCAGGCTG
CGGCAGTATGGGATAATCGGGAAAAGCGCGAACTGGCCAGACAGTCGGCATTGGAGGCTTTGGAGTGGGAAACGCAGGCA
GATTGCCGTCTGATGTTGCTGAAGGACGATGATTTTCCGGTGATGCTGGCCGAGGGCCTGACTCCTCCGCCCTTATTGTT
TTTGCGCGGCAATACCGCATTGCTGCACAGCCCGTCTGTCGCCATCGTCGGCAGTCGTCATGCTACGCCGCAAGCGGTTA
GAATTGCACGGGATTTTGGTGAGGCATTGGGTAAAGAAGGGATTACCGTGGTTTCCGGTATGGCTGCCGGAATTGATGCC
GCCGCCCATCAAGGTGCGTTGTTGGCAGACGGGGGCGGTACGATAGCTGTCTGGGGAACAGGCATCAACCGTATCTATCC
GCCGTCTAACAAGCAGCTTGCCTACGAAATTGCCGGACATGGTTTGATTGTCAGCGAATTTCCGCTGGGTACGCGGCCGC
TGGCGGGAAATTTTCCGCGGCGAAACCGTTTGATTGCCGCTTTATCCTGCGCTACATTGGTGGTCGAAGCAGCATTGGAA
TCAGGCTCGCTGATTACAACCAAACTTGCCGCCGAAATGGGGAGGGAAGTGATGGCGGTGCCCGGCTCGATTGATAATCC
GCACAGTAAAGGTTGCCACAAGCTGATTAAAGAAGGTGCAAAACTGGTGGAATGTTTAGATGATATTGTGCAAGAATGCC
CGCAGCTATTGCAAAATGCCTCCATATCATCATATTCTATAAATAAACAGCGGAAAAAAGCCGAAAGGCCGTCTGCAAAT
ACCCTGTCGGCAGCAAAAAACGAAAAATTGCCGTTGGCAGAGCCGGAAAAAAACCAAACCGAAGCAGTACGGCCGTCTGA
AAAAATACAGGCTGCCCAATCCGCGCAGGCAGACAGCATACTGGCGGCGATGGGCTACGATCCTGTCCACCCCGATATGC
TGGCGGCGCAAACAGGGCTGGCCGCTGCCGACATTTACGCCAAATTGTTGGAACATGAATTAGAAGGAACAGTTGCCGCG
CTTGCCGGAGGCCGTTACCAAAGAATAAGATGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-284)

• DprA winged helix domain (DprA_WH) (350-404)

3D structure

• AlphaFold DB: A0A5P3MWE4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria meningitidis strain C311	68.357	100	0.69
dprA	Neisseria meningitidis MC58	68.357	100	0.69
dprA	Neisseria gonorrhoeae MS11	67.317	100	0.673
dprA	Neisseria gonorrhoeae strain FA1090	67.317	100	0.673
dprA	Vibrio cholerae strain A1552	36.804	100	0.371