Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DXY21_RS19435 Genome accession   NZ_CP031694
Coordinates   3912040..3912696 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain SRCM101368     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 3907040..3917696
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXY21_RS19420 (DXY21_03908) spxH 3907279..3908181 (+) 903 WP_024085126.1 protease adaptor protein SpxH -
  DXY21_RS20500 (DXY21_03909) - 3908467..3908634 (+) 168 WP_003155026.1 hypothetical protein -
  DXY21_RS19425 (DXY21_03910) pepF 3908672..3910501 (-) 1830 WP_003155028.1 oligoendopeptidase F Regulator
  DXY21_RS19430 (DXY21_03911) - 3910729..3911889 (-) 1161 WP_060386867.1 competence protein CoiA family protein -
  DXY21_RS19435 (DXY21_03912) mecA 3912040..3912696 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  DXY21_RS20505 - 3912679..3912789 (-) 111 Protein_3812 adaptor protein MecA -
  DXY21_RS19440 (DXY21_03913) - 3912972..3913628 (+) 657 WP_003155033.1 TerC family protein -
  DXY21_RS19445 (DXY21_03914) spx 3913686..3914081 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  DXY21_RS19450 (DXY21_03915) - 3914260..3914838 (-) 579 WP_003155035.1 GNAT family N-acetyltransferase -
  DXY21_RS19455 (DXY21_03916) - 3914956..3916143 (-) 1188 WP_003155036.1 putative glycoside hydrolase -
  DXY21_RS19460 (DXY21_03917) oppF 3916250..3917167 (-) 918 WP_003155037.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=310430 DXY21_RS19435 WP_003155032.1 3912040..3912696(-) (mecA) [Bacillus velezensis strain SRCM101368]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=310430 DXY21_RS19435 WP_003155032.1 3912040..3912696(-) (mecA) [Bacillus velezensis strain SRCM101368]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCTGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCTTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGAAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment