Detailed information NTG0310404

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: ES298_RS10310
• Genome accession: NZ_CP038253
• Coordinates: 1980693..1983227 (-)
• Length: 844 a.a.
• NCBI ID: WP_084385399.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901929
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1975693..1988227

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES298_RS10295 (ES298_10835)	patB	1976295..1978061 (-)	1767	WP_000859851.1	multidrug efflux ABC transporter subunit PatB	-
ES298_RS10300	-	1978253..1978702 (+)	450	Protein_2012	transposase	-
ES298_RS10305 (ES298_10845)	patA	1978852..1980546 (-)	1695	WP_084385398.1	multidrug efflux ABC transporter subunit PatA	-
ES298_RS10310 (ES298_10850)	hexA	1980693..1983227 (-)	2535	WP_084385399.1	DNA mismatch repair protein MutS	Machinery gene
ES298_RS10315 (ES298_10855)	argR	1983278..1983724 (-)	447	WP_001231473.1	arginine repressor	-
ES298_RS10320 (ES298_10860)	argS	1983860..1985551 (+)	1692	WP_001092701.1	arginine--tRNA ligase	-
ES298_RS10325 (ES298_10865)	-	1985866..1986424 (-)	559	Protein_2017	transposase	-
ES298_RS10330 (ES298_10870)	-	1986410..1986895 (+)	486	WP_180378007.1	cupin domain-containing protein	-
ES298_RS10335 (ES298_10875)	-	1986979..1987686 (+)	708	WP_000166475.1	response regulator transcription factor	-

Sequence

Protein

• Length: 844 a.a.
• Molecular weight: 94904.47 Da
• Isoelectric Point: 5.0233

>NTDB_id=310404 ES298_RS10310 WP_084385399.1 1980693..1983227(-) (hexA) [Streptococcus pneumoniae strain TVO_1901929]
MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSKEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQTASSKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENTRSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELESLISAAIAP
EAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFG
DDSQIDIRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQLGSYVPAESAHLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLQHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTENPPPMRQTSA
VTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL

Nucleotide

• Length: 2535 bp

>NTDB_id=310404 ES298_RS10310 WP_084385399.1 1980693..1983227(-) (hexA) [Streptococcus pneumoniae strain TVO_1901929]
ATGGCGATAGAAAAGCTATCACCCGGCATGCAACAGTATGTGGATATTAAAAAGCAATATCCAGATGCTTTTTTGCTCTT
TCGGATGGGTGATTTTTATGAATTATTTTATGAGGATGCGGTCAATGCTGCGCAGATTCTGGAAATTTCCTTAACGAGTC
GCAACAAGAATGCCGACAATCCGATCCCTATGGCGGGTGTTCCCTATCATTCTGCCCAACAGTATATCGATGTCTTGATT
GAGCAGGGTTATAAGGTGGCTATCGCAGAGCAGATGGAAGATCCTAAACAAGCAGTTGGGGTTGTTAAACGAGAGGTTGT
TCAGGTCATTACGCCAGGGACAGTGGTCGATAGCAGTAAGCCGGACAGTCAGAATAATTTTTTGGTTTCCATAGACCGCG
AAGGCAATCAATTTGGCCTAGCTTATATGGATTTGGTGACGGGTGACTTTTATGTGACAGGTCTTTTGGATTTCACGCTG
GTTTGTGGGGAAATCCGTAACCTCAAGGCTCGAGAAGTGGTGTTGGGTTATGACTTGTCTAAGGAAGAAGAACAAATCCT
CAGCCGCCAGATGAATCTGGTACTCTCTTATGAAAAAGAAAGCTTTGAAGACCTTCATTTATTGGATTTGCGATTGGCAA
CGGTGGAGCAAACGGCATCTAGTAAGCTGCTCCAGTATGTTCATCGGACTCAGATGAGGGAATTGAACCACCTCAAACCT
GTTATCCGCTACGAAATTAAGGATTTCTTGCAGATGGATTATGCGACCAAGGCTAGTCTGGATTTGGTTGAGAATACTCG
CTCAGGTAAGAAACAAGGCAGTCTTTTCTGGCTTTTGGATGAAACCAAAACGGCTATGGGGATGCGTCTCTTGCGTTCTT
GGATTCATCGCCCCTTGATTGATAAGGAACGAATCGTCCAACGTCAAGAAGTAGTGCAGGTCTTTCTCGACCATTTCTTT
GAGCGTAGTGACTTGACAGACAGTCTCAAGGGTGTTTATGACATTGAGCGCTTGGCTAGTCGTGTTTCTTTTGGCAAAAC
CAATCCAAAGGATCTCTTGCAGTTGGCGACTACCTTGTCTAGTGTGCCACGGATTCGTGCGATTTTAGAAGGGATGGAGC
AACCTACTCTAGCCTATCTCATCGCACAACTGGATGCAATCCCTGAGTTGGAGAGTTTGATTAGCGCAGCGATTGCTCCT
GAAGCTCCTCATGTGATTACAGATGGGGGAATTATCCGGACTGGATTTGATGAGACTTTAGACAAGTATCGTTGCGTTCT
CAGAGAAGGGACTAGCTGGATTGCTGAGATTGAGGCTAAGGAGCGAGAAAACTCTGGTATCAGCACGCTCAAGATTGACT
ACAATAAAAAGGATGGCTACTATTTTCATGTGACCAATTCGCAACTGGGAAATGTGCCAGCCCACTTTTTCCGCAAGGCG
ACGCTGAAAAACTCAGAACGCTTTGGAACCGAAGAATTAGCCCGTATCGAGGGAGATATGCTTGAGGCGCGTGAGAAGTC
AGCCAACCTCGAATACGAAATATTTATGCGCATTCGTGAAGAGGTCGGCAAGTACATCCAGCGTTTACAAGCTCTAGCCC
AAGGAATTGCGACGGTTGATGTCTTACAGAGTCTGGCGGTTGTGGCTGAAACCCAGCATTTGATTCGACCTGAGTTTGGT
GACGATTCACAAATTGATATCCGGAAAGGGCGCCATGCTGTCGTTGAAAAGGTTATGGGGGCTCAGACCTATATTCCAAA
TACGATTCAGATGGCAGAAGATACCAGTATTCAACTGGTTACAGGGCCAAACATGAGTGGGAAGTCTACCTATATGCGTC
AGTTAGCCATGACGGCGGTTATGGCCCAGCTGGGTTCCTATGTTCCTGCTGAAAGCGCCCATTTACCGATTTTTGATGCG
ATTTTTACCCGTATCGGAGCAGCAGATGACTTGGTTTCGGGTCAGTCAACCTTTATGGTGGAGATGATGGAGGCCAATAA
TGCCATTTCGCATGCGACCAAGAACTCTCTCATTCTCTTTGATGAATTGGGACGTGGAACTGCAACTTATGACGGGATGG
CTCTTGCTCAGTCCATCATCGAATATATCCATGAGCACATCGGAGCTAAGACCCTCTTTGCGACCCACTACCATGAGTTG
ACTAGTCTGGAGTCTAGTTTACAACACTTGGTCAATGTCCACGTGGCAACTTTGGAGCAGGATGGGCAGGTCACCTTCCT
TCACAAGATTGAACCGGGACCAGCTGATAAATCCTACGGTATCCATGTTGCCAAGATTGCTGGCTTGCCAGCAGACCTTT
TAGCAAGGGCGGATAAGATTTTGACTCAGCTAGAGAATCAAGGAACAGAGAATCCTCCTCCCATGAGACAAACTAGTGCT
GTCACTGAACAGATTTCACTCTTTGATAGGGCAGAAGAGCATCCTATCCTAGCAGAATTAGCTAAACTGGATGTGTATAA
TATGACACCTATGCAGGTTATGAATGTCTTAGTAGAGTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	99.645	100	0.996
mutS	Pseudomonas stutzeri strain ATCC 17587	36.608	100	0.371